ASCO: High-Risk Prostate Cancer Diagnosis Up Since New PSA Recs

ASCO: High-Risk Prostate Cancer Diagnosis Up Since New PSA Recs

Researchers report 3 percent annual rise in intermediate- and high-risk cases

Two major studies strengthen case for prostate cancer drug before chemotherapy

The pioneering prostate cancer drug abiraterone can significantly extend the lives of men with advanced prostate cancer if administered prior to administering chemotherapy, according to phase III clinical trial data.

Study may support active surveillance for favorable intermediate-risk prostate cancer

New research suggests that active surveillance may be an initial approach for men with favorable intermediate-risk prostate cancer.

Most commonly used treatment for prostate cancer is radiotherapy

A recent study has determined that radiation therapy is the most common treatment for prostate cancer regardless of cancer stage, PSA level, or prognosis and risk rating.

Patients with detectable PSA after prostatectomy should receive more aggressive radiation therapy

Prostate cancer patients with detectable prostate specific antigen (PSA) following radical prostatectomy are advised to receive more aggressive radiation therapy treatment, according to a study.

Black men have lower preference for investigation of prostate cancer

Black men have lower preference for investigation of prostate cancer

Black men are less willing to be investigated for prostate cancer, thereby increasing the likelihood of being diagnosed.

ASCO: Active surveillance for prostate cancer may decrease survival odds for some

ASCO: Active surveillance for prostate cancer may decrease survival odds for some

When active surveillance is chosen, survival for intermediate-risk disease may be decreased.

ASCO: Testicular cancer history may indicate greater risk of developing prostate cancer

ASCO: Testicular cancer history may indicate greater risk of developing prostate cancer

Individuals who've had testicular cancer may be at increased risk for prostate cancer, but the overall risk is low, according to a study.

Radiation therapy used most often for prostate cancer regardless of decision-making factors

Radiation therapy used most often for prostate cancer regardless of decision-making factors

Most common treatment for prostate cancer is radiation therapy, regardless of cancer stage.

Considerable practice variation among surgeons in selecting patients for radical prostatectomy

Considerable practice variation among surgeons in selecting patients for radical prostatectomy

Variation was observed at a high-volume center when surgeons selected patients with low-risk prostate cancer to undergo radical prostatectomy, according to a study.

Drug combination suppresses growth of late-stage prostate cancer tumors

Low doses of metformin and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors.

Observation used increasingly in younger men with prostate cancer

Observation used increasingly in younger men with prostate cancer

From 2004 to 2009, marked increase in observation among men with low-risk prostate cancer has been observed.

ASCO endorses ACS recommendations for prostate cancer survivor care

ASCO endorses ACS recommendations for prostate cancer survivor care

Guideline outlines recommended follow-up care for prostate cancer survivors

Smoking linked to breast and prostate cancer

Smoking linked to breast and prostate cancer

Smoking is associated with an increased risk of breast cancer, prostate cancer, and routine infections.

Targeted MRI-ultrasound is better than standard biopsy at detecting high-risk prostate cancer

Targeted magnetic resonance (MR)/ultrasound fusion biopsy outperformed standard biopsy technique for increased detection of high-risk prostate cancer, according to a recent study.

Factors associated with emotional distress in newly-diagnosed prostate cancer identified

Factors associated with emotional distress in newly-diagnosed prostate cancer identified

Researchers identified certain factors associated with emotional distress in men with newly diagnosed prostate cancer.

Abiraterone improves survival in prostate cancer when given before chemo

Abiraterone improves survival in prostate cancer when given before chemo

Abiraterone significantly extends survival in men with advanced prostate cancer (PCa) if administered before chemotherapy.

New strategy proposed to overcome treatment resistance in prostate cancer

Researchers have identified two genes that appear to be simultaneously overexpressed in aggressive prostate cancers resistant to the androgen-targeted treatments enzalutamide and abiraterone acetate.

PDE-5 inhibitors linked to prostate cancer biochemical recurrence

PDE-5 inhibitors linked to prostate cancer biochemical recurrence

Phosphodiesterase type 5 inhibitors up the risk of biochemical recurrence after radical prostatectomy, according to a recent study.

Combination prostate biopsy could yield improved results

Combination prostate biopsy could yield improved results

Prostate biopsies that combine both magnetic resonance imaging (MRI) technology and ultrasound appear to give more accurate results, according to a new study.

Current smoking lowers survival odds for prostate cancer

Current smoking lowers survival odds for prostate cancer

Former, as well as current, smokers saw higher risk for disease recurrence and radiation therapy-related urinary side effects.

PDE-5 inhibitors increase risk of biochemical recurrence after radical prostatectomy

PDE-5 inhibitors increase risk of biochemical recurrence after radical prostatectomy

Taking phosphodiesterase type 5 inhibitors following radical prostatectomy is associated with an elevated risk of recurrence.

Smoking Increases Side Effect, Recurrence Risk in Prostate Cancer

Smoking Increases Side Effect, Recurrence Risk in Prostate Cancer

Recent study confirmed the effects on smoking on patients with prostate cancer.

New study helps physicians and patients determine prostate cancer risk

New study helps physicians and patients determine prostate cancer risk

Examining more distant relations for prostate cancer can provide important patient history.

Study examines vaccine therapy in prostate cancer with rising prostate-specific antigen (PSA) levels

A vaccine therapy designed to boost the body's immune response may join available early treatment options for prostate cancer.

Screening based on family history of prostate cancer linked to prostate cancer-specific mortality

Screening based on family history of prostate cancer linked to prostate cancer-specific mortality

Focusing screening efforts on those with a positive family history of prostate cancer could be more effective.

Radiation plus hormone therapy prolongs survival for older men with prostate cancer

The addition of radiation treatment to hormone therapy reduced more cancer deaths among older men locally advanced prostate cancer, compared to hormone therapy alone.

Understanding the male patient with cancer

Understanding the male patient with cancer

How men perceive their role within their family dynamic or social circles may impact how they respond to a cancer diagnosis. Often they retreat or shut down, further challenging the efforts of their oncology care providers and loved ones to help them cope.

Family history of prostate cancer should include second- and third-degree relatives

Family history of prostate cancer should include second- and third-degree relatives

A man's second-, third-degree relatives may be as significant as looking at his first-degree relatives to determine risk for developing prostate cancer.

Green tea consumption may prevent, treat prostate cancer

Green tea consumption may prevent, treat prostate cancer

Green tea may have a role a in the prevention and treatment of prostate cancer and other prostate conditions like prostatitis.

Life expectancy still not used to determine aggressiveness of prostate cancer treatment

More than half of prostate cancer patients age 66 years and older have life expectancies of less than 10 years, yet half of them were over-treated for their prostate cancer with surgery, radiation, or brachytherapy.

Physical activity and survival among men diagnosed with prostate cancer

Physical activity and survival among men diagnosed with prostate cancer

This study investigated the effect of physical activity after a prostate cancer diagnosis on both overall and prostate cancer-specific mortality in a large cohort.

Long-term testosterone therapy does not increase risk of prostate cancer

Current evidence seems to indicated that withholding T therapy in hypogonadal men cannot be justified.

HIV drug blocks bone metastases in prostate cancer

HIV drug blocks bone metastases in prostate cancer

Although prostate cancer can be successfully treated in many men, if the disease metastasizes to the bone, it is eventually lethal.

Aspirin and/or NSAID use may improve risk of high-grade prostate cancer

Aspirin and/or NSAID use may improve risk of high-grade prostate cancer

A recent meta-analysis demonstrated an association between aspirin and a reduced risk of prostate cancer.

Galeterone active in one form of castration-resistant prostate cancer

The anticancer drug galeterone has proved successful in lowering prostate-specific antigen levels in men with castration-resistant prostate cancer (CRPC).

Not enough prostate cancer patients receive bisphosphonates

Not enough prostate cancer patients receive bisphosphonates

Men receiving hormone therapy for prostate cancer may be missing out on protective meds, researchers say.

Killing cancer by protecting normal cells

A new anticancer drug, already in clinical development, may help spare healthy cells from the effects of radiation treatments.

Personalized genetic test predicts recurrence risk for prostate cancer

A genetic test has been developed to identify which men are at higher risk for prostate cancer recurrence after localized treatment with surgery or radiotherapy.

High phosphorous intake associated with increased risk of lethal prostate cancer

High phosphorous intake associated with increased risk of lethal prostate cancer

Phosphorous is independently associated with the risk of developing lethal and high-grade prostate cancer.

Conventional therapies are less effective in prostate cancer with BRCA mutations

Prostate cancer patients with hereditary mutations in the BRCA genes do not respond as well to conventional treatment such as surgery and radiotherapy, and they have a lower survival rate than patients who do not have these genetic mutations.

BRCA-related tumors respond to olaparib

Olaparib, an experimental oral cancer drug, has shown an overall tumor response rate of 26% in advanced cancers associated with BRCA1 and BRCA2 mutations, according to recent research.

Study investigating advanced MRI scans to detect prostate cancer set to begin

Study investigating advanced MRI scans to detect prostate cancer set to begin

A new technique that employs advanced MRI scans to diagnose prostate cancer is being tested in a nationwide trial.

Metformin use may be associated with decreased risk of prostate cancer

Metformin use may be associated with decreased risk of prostate cancer

Metformin use associated with decreased risk of prostate cancer diagnosis while other oral antihyperglycemics had no decreased risk.

Most internet sites on prostate cancer disagree with expert panel's recommendations

Most internet sites on prostate cancer disagree with expert panel's recommendations

Less than 20 percent of top-ranked health sites advise against screening for prostate cancer, a recommendation made by the USPSTF.

Active surveillance of prostate cancer leads to improved quality of life

Active surveillance of prostate cancer leads to improved quality of life

Active surveillance allows men with prostate cancer to delay or avoid the side effects of its treatment as well.

Video-based tool informs patients about prostate health

Video-based tool informs patients about prostate health

A video-based educational tool increased comprehension of prostate health terms in patients with a mean literacy level of 7th grade or higher.

Personalized medicine and the role of the navigator: Prostate cancer

Personalized medicine and the role of the navigator: Prostate cancer

Molecular tests are poised to become a part of the treatment guidelines for prostate cancer. These tests provide information that extends beyond just identifying the type of cancer a patient has; they can also help narrow down treatment options to those that offer the best outcomes for patients.

Prostate cancer medications linked to increased heart-related deaths in some men

Some prostate cancer medications are linked to an increased risk of dying from heart-related causes in men with congestive heart failure or with a history of prior heart attacks.

ASCO endorses guideline for adjuvant and salvage radiotherapy after prostatectomy

ASCO endorses guideline for adjuvant and salvage radiotherapy after prostatectomy

The endorsed guideline outlines use of adjuvant and salvage radiotherapy after surgery for prostate cancer.

Androgen deprivation therapy may increase risk of cardiac-related death in patients with cardiac issues

Androgen deprivation therapy may increase risk of cardiac-related death in patients with cardiac issues

Men who were treated with androgen deprivation therapy for prostate cancer have a three times increased risk of cardiac problems.

Daily aspirin may lower mortality in nonmetastatic prostate cancer

Daily aspirin may lower mortality in nonmetastatic prostate cancer

Even a small daily dose of aspirin may help lower mortality among men with nonmetastatic prostate cancer, according to research.

Ten portions of tomatoes per week decreases risk of prostate cancer

Ten portions of tomatoes per week decreases risk of prostate cancer

Consuming 10 portions of tomatoes a week can reduce risk for developing prostate cancer by 18%.

For patients with localized prostate cancer, androgen deprivation therapy may be harmful

For patients with localized prostate cancer, androgen deprivation therapy may be harmful

Primary androgen deprivation therapy (PADT) was linked with increased all-cause mortality and prostate cancer-specific mortality.

For patients with low-risk prostate cancer managed with active surveillance, obesity may increase risk of progression

For patients with low-risk prostate cancer managed with active surveillance, obesity may increase risk of progression

Obesity is linked with increased risk of progression of low-risk prostate cancers in active surveillance.

Overdetection of PSA recurrence after radical prostatectomy more likely in older patients

Overdetection of PSA recurrence after radical prostatectomy more likely in older patients

For some men, prostate cancer recurrence may be overdetected, especially in those aged over 70.

Half of patients who die from prostate cancer have metastases at diagnosis

Half of patients who die from prostate cancer have metastases at diagnosis

Researchers sought to determine which types of patients die from prostate cancer in the modern era.

Increased PSA after prostatectomy may not result in metastasis in some men's lifetime

Increased PSA after prostatectomy may not result in metastasis in some men's lifetime

Some patients whose PSA levels become elevated after prostatectomy may die as a result of a cause unrelated to prostate cancer.

Elevated cholesterol associated with prostate cancer recurrence

Elevated cholesterol associated with prostate cancer recurrence

Findings suggest that elevated levels of cholesterol and triglycerides may be linked with greater risk of the prostate cancer recurrence, but normalization of blood fats may reduce risk.

Professional recommendations against prostate cancer screening have little impact on practice

The effect of guidelines recommending that elderly men should not be routinely screened for prostate cancer has been minimal at best, according to a new study.

High HDL may reduce risk of prostate cancer recurrence

High HDL may reduce risk of prostate cancer recurrence

High cholesterol may be associated with an increased risk for developing prostate cancer.

Testosterone may increase risk for developing prostate cancer

Testosterone may increase risk for developing prostate cancer

Testosterone increased the risk for developing prostate cancer in rats.

Aspirin may decrease the risk for developing high-grade prostate cancer

Aspirin may decrease the risk for developing high-grade prostate cancer

Aspirin and other other NSAIDs were associated with a decreased risk for developing an aggressive form of prostate cancer.

Facing prostate cancer—but not alone

Facing prostate cancer—but not alone

Frank dela Rama, a new member of the Oncology Nurse Advisor editorial board, talks about helping men with newly diagnosed prostate cancer learn about and prepare to cope with their disease.

Prostate cancer treatment controversy continues as study finds watchful waiting not enough for some men

An active controversy among oncologists concerns watchful waiting versus more active treatment for prostate cancer.

Men who are uneducated about their prostate cancer have difficulty making treatment decisions

Researchers have discovered that men who are not well educated about their prostate cancer have a much more difficult time deciding on treatment options.

Wild berry may up chemotherapy effectiveness for pancreatic cancer

Wild berry may up chemotherapy effectiveness for pancreatic cancer

Chokeberry extract enhances cytotoxicity of gemcitabine on a single cancer cell line, according to research.

For prostate cancer screening, guidelines have little effect on clinical practice

For prostate cancer screening, guidelines have little effect on clinical practice

Guidelines recommending clinicians not routinely screen elderly men for prostate cancer have had a minimal effect on practice.

ASTRO: Sexual function not compromised in prostate cancer combo treatment

ASTRO: Sexual function not compromised in prostate cancer combo treatment

High rates of preserved sexual function seen with combination beam plus brachytherapy for prostate cancer.

ASTRO: Prostate cancer recovery faster with less androgen deprivation therapy

ASTRO: Prostate cancer recovery faster with less androgen deprivation therapy

Shorter time to testosterone recovery with 18 versus 36 months androgen deprivation therapy.

Certain male baldness pattern associated with increased risk of aggressive prostate cancer

Certain male baldness pattern associated with increased risk of aggressive prostate cancer

Baldness in men at age 45 is linked with an elevated risk for developing aggressive prostate cancer.

For black men with prostate cancer, watchful waiting may be unwise

For black men with prostate cancer, watchful waiting may be unwise

For men with early-stage prostate cancer, watching waiting is not always the best course of action, especially for black patients.

Enzalutamide reduces skeletal-related events in men with advanced castration-resistant prostate cancer

Enzalutamide reduces skeletal-related events in men with advanced castration-resistant prostate cancer

Enzalutamide was found to decrease the risk of skeletal-related events in men with metastatic castration-resistant prostate cancer.

Joint ASCO/CCO guidelines for advanced prostate cancer issued

Joint ASCO/CCO guidelines for advanced prostate cancer issued

Recommendations are for men whose tumors have grown resistant to hormonal therapies were issued jointly by the American Society of Clinical Oncology (ASCO) and Cancer Care Ontario (CCO) in Canada.

Robotic surgery for prostate cancer is widespread in the United States

There has been widespread adoption in the United States of robot-assisted prostatectomy to treat prostate cancer in recent years.

In prostate cancer, watchful waiting may not be best for African Americans

In prostate cancer, watchful waiting may not be best for African Americans

African American men may not benefit from watchful waiting after being diagnosed with low-grade prostate cancer.

For prostate cancer screening, new technique may prove effective

For prostate cancer screening, new technique may prove effective

Researchers have designed a new, non-invasive technique to screen for prostate cancer.

Lacking prostate cancer knowledge linked to greater decisional conflict

Lacking prostate cancer knowledge linked to greater decisional conflict

For economically disadvantaged men with newly diagnosed prostate cancer, poor knowledge about prostate cancer is associated with increased decisional conflict.

Prostate Cancer Prevention Trial identifies men most likely to undergo biopsy

Healthy men participating in the Prostate Cancer Prevention Trial who actively participate in all trial steps are most likely to undergo a biopsy at the end of the trial, according to recent research.

Prostate cancer education is key for patient decision-making

Prostate cancer education is key for patient decision-making

Researchers found that men who aren't well educated about prostate cancer have more difficulty making decisions.

Prostate cancer risk cut by tomatoes

Prostate cancer risk cut by tomatoes

Men who eat more than 10 portions of tomatoes each week have an 18% lower risk of developing prostate cancer.

Upgraded Prostate Cancer Risk Calculator 2.0, with emojis, is available online

A calculator to help men and their doctors assess the risk of prostate cancer has had a major upgrade to enhance men's and their physicians' understanding of a man's risk of prostate cancer.

Men in prostate cancer prevention trial more likely to undergo biopsy

Men in prostate cancer prevention trial more likely to undergo biopsy

Men without prostate cancer taking part in the trial who participate in other aspects are most likely to undergo a challenging biopsy.

Lasting drop in prostate cancer mortality with prostate-specific antigen (PSA)

Lasting drop in prostate cancer mortality with prostate-specific antigen (PSA)

Prostate-specific antigen (PSA) screening is associated with a lasting reduction in prostate cancer mortality, according to a study published online.

Genomic analysis of prostate cancer suggests best plan after surgery

Genomic analysis of prostate cancer suggests best plan after surgery

A genomic tool can help doctors and patients make a more informed decision on the need for radiation therapy after surgery for prostate cancer.

Prior diagnosis of depression worsens outcomes in prostate cancer

Prior diagnosis of depression worsens outcomes in prostate cancer

Men with diagnosed depressive disorders are less likely to pursue definitive treatment options for prostate cancer and more likely to have poorer outcomes.

Robot-assisted surgery for prostate cancer controls disease for 10 years

Robot-assisted surgery to remove cancerous prostate glands is effective in controlling the disease for 10 years, according to a new study.

Tips for Patients and Their Partners for Restoring Intimacy after Prostate Cancer

Tips for Patients and Their Partners for Restoring Intimacy after Prostate Cancer

Although their lives eventually return to normal after treatment, some men have to cope with lingering effects of their treatment that affects their libido or sexual function. Daniel Watter, EdD, offers guidance tips to share with patients who are surviving prostate cancer that can help them through the recovery process.

New epigenetic test could eliminate unnecessary repeat biopsies for prostate cancer

Two independent trials have validated the performance of an epigenetic test that could provide physicians with a better tool to help eliminate unnecessary repeat prostate biopsies.

Genetics is the dominant risk factor for familial breast, prostate, and colorectal cancers

Genetics is the dominant risk factor for familial breast, prostate, and colorectal cancers

A study of people who were adopted identified genetics as the dominant risk factor in familial breast, prostate, and colorectal cancers.

Vasectomy may increase risk of aggressive prostate cancer

Vasectomy may increase risk of aggressive prostate cancer

Vasectomy was associated with a small increased risk of prostate cancer, and a stronger risk for advanced or lethal prostate cancer, according to a new study.

Obtaining 16 cores is better than obtaining 12 cores for prostate cancer detection

Obtaining 16 cores is better than obtaining 12 cores for prostate cancer detection

A research team from Japan found that 16-core biopsy has a slightly higher detection rate than 12-core biopsy.

Bike riding may up prostate cancer risk

Bike riding may up prostate cancer risk

Researchers found that cyclists who bike more may face a higher risk of prostate cancer, but not a greater chance of infertility or erectile dysfunction.

Rates of observation as prostate cancer management vary

Rates of observation as prostate cancer management vary

Rates of observation as management for low-risk prostate cancer vary widely, and primary ADT is not tied to better survival for men with localized prostate cancer.

Robot-assisted surgery effective in controlling prostate cancer for 10 years

Robot-assisted surgery effective in controlling prostate cancer for 10 years

Results of a new study show that robot-assisted surgery to remove cancerous prostate glands is effective in controlling the disease for 10 years.

Link between vasectomy and prostate cancer greater in high-grade cases

Link between vasectomy and prostate cancer greater in high-grade cases

Vasectomy is associated with an increased incidence of prostate cancer overall during extended follow-up, with an elevated risk seen for high-grade and lethal cancer.

Depressed men with prostate cancer have worse outcomes

Depressed men with prostate cancer have worse outcomes

Depressed men with a diagnosis of intermediate- or high-risk prostate cancer have worse overall outcomes.

Doctors steer prostate cancer treatment choices

Doctors steer prostate cancer treatment choices

Physicians who diagnosed low-risk prostate cancer had more influence over the decision to enter active surveillance than did the disease characteristics, according to a case review.

Radiation-induced toxicity risk in prostate cancer predicted by variations in key gene

Key genetic variants may affect how cancer patients respond to radiation treatments, according to a new study.

Researchers Identify New Cancer Metastasis-Suppressor Gene

Researchers Identify New Cancer Metastasis-Suppressor Gene

Researchers searching for a target that would interfere with cancer metastasis identified a new suppressor of metastasis that may lead toward the development of more effective treatments for prostate cancer and other malignant solid tumors.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs