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PROLASTIN-C
Inborn errors of metabolism
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Drug Name:

PROLASTIN-C Rx

Generic Name and Formulations:
Alpha1-proteinase inhibitor (human) 1000mg/vial; lyophilized pwd for IV infusion after reconstitution; preservative-free.

Company:
Grifols Biologicals, Inc.

Therapeutic Use:

Indications for PROLASTIN-C:

For chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe alpha1-proteinase inhibitor deficiency.

Adult:

Give by IV infusion at a rate of 0.08mL/kg/min. 60mg/kg once weekly.

Children:

Not established.

Contraindications:

IgA deficient patients with antibodies against IgA.

Warnings/Precautions:

Contains human plasma; monitor for possible infection transmission (eg, viruses, Creutzfeldt-Jakob disease agent). Pregnancy (Cat.C). Nursing mothers.

Adverse Reactions:

Upper respiratory tract infection, UTI, nausea, pain, chills, cough, dizziness, dyspnea, headache, hot flush, oral candidiasis; rash, hypersensitivity reactions (discontinue if occur).

How Supplied:

Single-use vial—1 (w. diluent + needles)

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