Applying evolutionary theory improves the accuracy of predicting in which patients Barrett's esophagus will progress to esophageal adenocarcinoma.
Presence of certain microRNAs (miRNAs) is predictive of response to TKIs and prognosis for patients with metastatic renal cell carcinoma (mRCC).
Survival among women age 40 years and younger with breast cancer appears to vary according to breast cancer subtype, with age particularly prognostic for women with luminal type breast cancers.
Advanced Cancer Patients Often Unaware That They Are More Optimistic About Their Prognosis Than Their OncologistsJuly 27, 2016
Most patients with advanced cancer report far more optimistic expectations for survival prognosis than their oncologists because patients misunderstand their oncologists' clinical judgment.
Patients with kataegis, a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome, have less invasive tumors and better prognoses.
Telomere length is predictive for determining which children treated for AML are at highest risk for delayed recovery, a finding that may have significant implications for treatment-related morbidity and mortality.
Biochemical Marker Is a Better Predictor of Adverse Effects in Patients with Non-small Cell Lung CancerJune 13, 2016
Albumin concentration with an established cutoff point is proven a better predictor of both chemotherapy toxicity and survival in patients with advanced lung cancer.
Progression-free and Overall Survival Better With Mutations Affecting DNA Repair Genes in Ovarian CancerApril 08, 2016
Women with advanced ovarian cancer who had mutations affecting DNA repair genes had longer progression-free and overall survival than women without the mutations.
Disparities Related to Race, Insurance, and Facility Type Affect Use of Genetic Assay in Breast CancerApril 01, 2016
Use and clinical implications of a test commonly used to predict the aggressiveness of early stage ER-positive breast cancer is influenced by patient's race, insurance, and type of facility.
Prolonged nightly fasting may reduce the risk of recurrence for patients with breast cancer.
Optimal risk stratification differs between male and female breast cancers. Outcomes for male patients with breast cancer were not significantly correlated with histologic grade, unlike for female patients.
Both insufficiency and deficiency of serum vitamin D correlated with an increased risk of unfavorable pathology in men undergoing radical prostatectomy for prostate cancer.
Combining a maximal debulking strategy and intraperitoneal chemotherapy could maximize the chance of achieving a cancer-free state, as explained in a recent clinical perspective piece.
Prognosis for patients with cutaneous melanoma may be predicted by an inherited genetic marker providing a personalized tool to gauge a person's survival and determine if closer monitoring is needed in the years following surgery.
Lymphomatoid papulosis (LyP) is an indolent cutaneous lymphoma; however, prognosis is worse if LyP is associated with lymphoma. A review of FSGCL dermatology departments identifies main risk factors and frequency of associated lymphoma.
Depression is a significant predictor of 5-year survival and recurrence in patients with head and neck cancer. These findings represent one of the largest studies to report on the impact of depression on cancer survival.
Researchers identified a biomarker that detects the most common type of lung cancer in its earliest stage. The discovery could one day change how long lung cancer patients live.
Screening for and treatment of ductal carcinoma in situ (DCIS) is found to prevent subsequent invasive cancer.
A signaling pathway present in most organisms suppresses the formation of specific types of brain tumor.
EPclin Score Provides More Prognostic Information for Residual Distant Recurrence in ER+/HER2- Breast CancerDecember 10, 2015
EndoPredict (EP) provided superior information to the Oncotype DX recurrence score (RS) for distant recurrence (DR) in overall, N+, and N- patient populations, and also pinpointed a low-risk patient group who may not need chemotherapy.
The size of a surgically removed tumor is generally thought to relate to the risk of metastasis; however, tumor cells metastasize at different times therefore the rate of spread is difficult to assess. A mathematical model was developed to calculate the relationship between tumor size and the relative risk of recurrence after surgery.
A personalized testing method may quickly and more accurately predict the effectiveness of a treatment for multiple myeloma in individual patients. The process may also aid patients with leukemia or lymphoma.
Incurable astrocytomas grow into healthy brain tissue like mycelium. Therefore, these tumors cannot be completely removed by surgery and invariably start growing again at some point despite intensive treatment.
A widely available, inexpensive blood test can predict outcomes and guide treatment in pancreatic cancer; however, only 1 in 5 US patients with the disease have the blood test.
A large international study shows that breastfeeding is associated with a lower risk of developing hormone-receptor-negative breast cancer. This breastfeeding meta-analysis shows the risk was reduced by up to 20% in women who breastfed.
Many types of leukemia are caused by loss of enzymes such as Pten, or conversely, the over-activation of enzymes that normally enhance cell proliferation, such as Shp2. But researchers have now found that a lack of both Pten and Shp2 results in an inability produce and sustain enough red blood cells.
Among children with intermediate-risk rhabdomyosarcoma that is negative for a fusion gene, those who had a high score of the specific gene signature MG5 had poorer survival outcomes compared with those who had a low score of MG5.
An experimental gene therapy essentially doubled the overall survival of patients with recurrent glioblastoma compared with the current standard of care.
Cancer specialists have long looked at genetic mutations and DNA copy changes to predict patient survival and drug sensitivity. A study has opened up yet another avenue for understanding why some people live longer or respond better to treatment.
Imaging Method Has Potential to Predict Effectiveness of Induction Chemotherapy in Patients With Head and Neck CancerOctober 01, 2015
Researchers identified a potential new way to predict which patients with head and neck cancer will benefit most from chemotherapy.
- More Than Half of Melanomas Are Self-Detected, Especially by Women
- Childhood Cancer Linked to Poor Diet Quality in Adult Survivors
- New Research Identifies Potential Bladder Cancer Chemotherapy Side Effect
- Olaratumab in Combo With Doxorubicin Approved for Soft Tissue Sarcoma
- Hydroxyurea May Improve Kidney Function in PV-Associated Nephrotic Syndrome
- Overall Benefits of Vaporized Nicotine Products Outweigh Harms, Says International Panel of Experts
- Nurse Residency Programs Can Impact Oncology Nursing Practice, Outcomes
- Implementing a Distress Screening Process for Cancer Patients
- Initiating Palliative Care in the Emergency Department
- Exercise is as Effective in Treating Metastatic Prostate Cancer as Medication
- Adherence to Tamoxifen, AIs Among Older Women is Low, Study Shows
- Replacing Neoadjuvant CRT with Multiagent Chemo Not Recommended for Rectal Cancer
- Study Identifies Factors Associated With Infection-related Complications in ALL
- Immune Checkpoint-Related Neurotoxicity May Be More Common During Combination Treatment
- New Recommendations for Secondary Prevention of Cervical Cancer
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