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PREVNAR
Vaccines
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Drug Name:

PREVNAR Rx

Generic Name and Formulations:
Pneumococcal 7-valent conjugate vaccine (diphtheria CRM197 protein) 16micrograms of saccharides per 0.5mL; susp for IM inj; contains aluminum.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for PREVNAR:

Immunization of infants and toddlers against invasive disease and otitis media caused by S. pneumoniae due to serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F.

Adult:

Not recommended.

Children:

Each dose is 0.5mL IM into the anterolateral thigh for infants or the deltoid muscle for toddlers and children; avoid nerves and blood vessels. May pretreat with antipyretic. <6weeks: not recommended. ≥6weeks: 4 doses usually given at 2, 4, 6, and 12–15 months of age (may start at 6 weeks of age: give 1st three doses 4–8 weeks apart, and 4th dose at least 2 months after 3rd dose). Previously unvaccinated older infants and children: 7–11months of age: 3 doses (2nd dose at least 4 weeks after 1st dose, 3rd dose after 1st birthday and at least 2 months after 2nd dose); 12–23months of age: 2 doses at least 2 months apart; 2–9yrs of age: 1 dose once.

Contraindications:

Allergies to any diphtheria toxoid-containing vaccine.

Warnings/Precautions:

May defer in acute moderate or severe febrile illness. Immunocompromised. Not a substitute for diphtheria, or for 23-valent polysaccharide pneumococcal vaccinations. Coagulation disorders. Have epinephrine inj available. Premature infants. Pregnancy (Cat.C), nursing mothers: not recommended.

Interactions:

Immunosuppressants (eg, radiation, chemotherapy, high-dose steroids): may get suboptimal response.

Pharmacological Class:

PCV.

Adverse Reactions:

Inj site reactions, irritability, drowsiness, fever, restless sleep, decreased appetite, vomiting, diarrhea, rash, hives; rare: febrile seizures.

How Supplied:

Single-dose syringes—10

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