In this review, investigators discuss current and emerging treatments for acute lymphocytic leukemia and acute myeloid leukemia in pediatric patients.
Risk of developing cancer as a result of childhood exposure to medical imaging radiation is not increased in children or adults, a new study reports.
The Pediatric Cancer Working Group of the AACR released its first consensus screening guidelines for children with common cancer predisposition syndromes.
Children and adolescent patients with cancer are able to accurately report subjective adverse events (AEs) they experience during their cancer treatment, and they are willing to do so.
The medications so far show little efficacy in children with cancer, but new studies may provide clues to how to change this, pediatric oncologist says.
Children with extramedullary relapse of CD19+ acute lymphoblastic leukemia experienced a potent and durable response to the immunotherapy.
Pediatric patients are better able to tolerate radiation therapy without anesthesia when video movies are projected on the inside of the machine during treatment.
Oncolytic variants of the HSV-1 have successfully treated melanoma, glioma, and other cancers in adults; in this study, researchers test the effectiveness of an oncolytic HSV-1 in pediatric patients.
AYAs continue to report lower social functioning scores than their peers 2 years after diagnosis.
Dr Lori Baudino, a clinical psychologist and dance/movement therapist, discusses a program that helps children with cancer cope with their disease and treatment, and learn to be children again.
[OncoTargets and Therapy] This research presents an overview of patient and disease management in pediatric pediatric papillary thyroid (PTC) patients.
New Oral Therapy Shows Promise Against Neurofibromatosis Type 1-Related Plexiform Neurofibromatomas in ChildrenJanuary 03, 2017
In this clinical trial, researchers determined the safety and efficacy of selumetinib, a selective MEK inhibitor, in children with NF1-related neurofibromas.
Studies of end-of-life (EOL) care for pediatric patients have been limited to single institutions or lacked detailed clinical data. Therefore, researchers conducted a retrospective cohort study to examine predictor of, and trends in, high-intensity EOL care in this patient population.
Dexrazoxane has cardioprotective properties that can prevent long-term cardiotoxicity in pediatric patients receiving chemotherapy, according to a review of the medical literature on cardiotoxic effects of anthracycline treatment.
Ambulatory bloodstream infections in pediatric oncology and stem cell transplant patients result in significant health care charges and extended hospital admissions.
The Multinational Association of Supportive Care in Cancer and the European Society for Medical Oncology updated their 2009 consensus recommendations for the prevention of acute CINV in pediatric patients with cancer.
Telomere length is predictive for determining which children treated for AML are at highest risk for delayed recovery, a finding that may have significant implications for treatment-related morbidity and mortality.
Pediatric patients with ALL treated with methotrexate can experience challenges with mental flexibility and organization compared with expectations from the general population.
Two new compounds suppress tumor growth in cell culture and mouse xenograft models of Ewing sarcoma, a rare pediatric cancer. These 2 compounds are similar to mithramycin, also known as picamycin, a drug no longer manufactured due to its toxicity.
Chemotherapy agents commonly used to treat childhood cancer impair eyesight in a way that indicates an impact on the CNS. The damage occurs to the patient's eye motor skills.
Outcomes from a novel personalized cell therapy may be improved if specific subtypes of T cells are selected to attack diseases such as acute lymphoblastic leukemia and lymphoma.
A group of pediatric oncology psychosocial experts developed evidence-based standards for the care of children with cancer and their families.
A framework has been issued to avoid waste and guide difficult prioritization decisions among children who need scarce life-saving chemotherapy treatment.
[OncoTargets and Therapy] Anaplastic large cell lymphoma (ALCL) frequently involves the bone marrow, but primary or secondary involvement to the bone is rare. This article examines a case of anaplastic lymphoma kinase positive ALCL with prominent bone involvement in a young boy.
African-American pediatric patients with Hodgkin lymphoma still display a considerable survival disparity when compared to their white and Hispanic peers.
New research has helped influence the FDA's decision to approve the first immunotherapy for pediatric patients.
Early cardiovascular events are a risk for survivors of childhood cancer, according to researchers who also advocate for a unified definition of pediatric metabolic syndrome.
The Pediatric Home Care/Expenditure Classification Model (P/ECM): A Home Care Case-Mix Model for Children Facing Special Health Care ChallengesJanuary 29, 2016
[Health Services Insights] This research explores the use of case-mix payment systems for younger patients with cancer.
Researchers in pediatric oncology identified a powerful new drug with unparalleled strength against neuroblastomas that resist treatment with crizotinib.
Researchers hope to prove the positive effects of the use of therapy dogs in pediatric oncology.
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