Studies of end-of-life (EOL) care for pediatric patients have been limited to single institutions or lacked detailed clinical data. Therefore, researchers conducted a retrospective cohort study to examine predictor of, and trends in, high-intensity EOL care in this patient population.
Dexrazoxane has cardioprotective properties that can prevent long-term cardiotoxicity in pediatric patients receiving chemotherapy, according to a review of the medical literature on cardiotoxic effects of anthracycline treatment.
Ambulatory bloodstream infections in pediatric oncology and stem cell transplant patients result in significant health care charges and extended hospital admissions.
The Multinational Association of Supportive Care in Cancer and the European Society for Medical Oncology updated their 2009 consensus recommendations for the prevention of acute CINV in pediatric patients with cancer.
Telomere length is predictive for determining which children treated for AML are at highest risk for delayed recovery, a finding that may have significant implications for treatment-related morbidity and mortality.
Pediatric patients with ALL treated with methotrexate can experience challenges with mental flexibility and organization compared with expectations from the general population.
Two new compounds suppress tumor growth in cell culture and mouse xenograft models of Ewing sarcoma, a rare pediatric cancer. These 2 compounds are similar to mithramycin, also known as picamycin, a drug no longer manufactured due to its toxicity.
Chemotherapy agents commonly used to treat childhood cancer impair eyesight in a way that indicates an impact on the CNS. The damage occurs to the patient's eye motor skills.
Outcomes from a novel personalized cell therapy may be improved if specific subtypes of T cells are selected to attack diseases such as acute lymphoblastic leukemia and lymphoma.
A group of pediatric oncology psychosocial experts developed evidence-based standards for the care of children with cancer and their families.
A framework has been issued to avoid waste and guide difficult prioritization decisions among children who need scarce life-saving chemotherapy treatment.
[OncoTargets and Therapy] Anaplastic large cell lymphoma (ALCL) frequently involves the bone marrow, but primary or secondary involvement to the bone is rare. This article examines a case of anaplastic lymphoma kinase positive ALCL with prominent bone involvement in a young boy.
African-American pediatric patients with Hodgkin lymphoma still display a considerable survival disparity when compared to their white and Hispanic peers.
New research has helped influence the FDA's decision to approve the first immunotherapy for pediatric patients.
Early cardiovascular events are a risk for survivors of childhood cancer, according to researchers who also advocate for a unified definition of pediatric metabolic syndrome.
The Pediatric Home Care/Expenditure Classification Model (P/ECM): A Home Care Case-Mix Model for Children Facing Special Health Care ChallengesJanuary 29, 2016
[Health Services Insights] This research explores the use of case-mix payment systems for younger patients with cancer.
Researchers in pediatric oncology identified a powerful new drug with unparalleled strength against neuroblastomas that resist treatment with crizotinib.
Researchers hope to prove the positive effects of the use of therapy dogs in pediatric oncology.
Comprehensive genomic screening may be warranted for all pediatric patients with cancer, not just those with a family history of cancer, according to results of a detailed analysis of germline mutations in cancer predisposition genes.
Ethnic, racial, and socioeconomic disparities appear to exist among children with retinoblastoma, a once uniformly fatal but now treatable eye cancer. Those disparities are associated with greater risks for advanced disease and undergoing removal of the eye.
Children with Wilm's tumor who are at low risk for relapse can be given less intensive treatment by omitting doxorubicin from the treatment regimen.
A new nationwide survey has indicated that the number of pediatric cancer patients being treated with proton radiation therapy is on the rise.
Use of straightforward, age-appropriate language is essential to communicating with pediatric oncology patients about their cancer and treatments, and gaining their trust in the medical team.
Modifying pediatric cancer treatments may reduce occurrence of late effects and promoting early detection, indicated data from a 5-year analysis of childhood cancers survivors presented at ASCO 2015.
Increasing the dose of radiotherapy given to children with an intracranial ependymoma can significantly improve their survival.
Premier study examines current delivery of patient/family education to pediatric patients with newly diagnosed cancer.
A measurement of the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy may allow for better matching of patients to the optimal intensity of chemotherapy.
Listening to music or audiobooks has a profound impact on postoperative pain perception in children. The benefit is increased when the patients are allowed to choose their own music or stories.
There is increasing evidence that adolescent and young adult patients with acute lymphoblastic leukemia (ALL) tend to fare better when treated with high-intensity pediatric protocols than standard adult regimens.
An innovative cell therapy against a highly aggressive form of acute lymphoblastic leukemia (ALL) continues to show highly promising results in children treated in a pilot study. At 1 month after treatment, 92% of the 39 children receiving bioengineered T cells had no evidence of cancer.
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- Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer
- LIVESTRONG Exercise Program Improves QoL in Cancer Survivors
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- Vaccine Enters Phase I Study for Safety and Effectiveness in Multiple Myeloma
- Timing Chemotherapy Administration to Circadian Rhythm Improves Drug Effectiveness
- New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases
- Profile of Tivantinib and its Potential in the Treatment of Hepatocellular Carcinoma: the evidence to date
- RANKL Inhibition May Represent Promising Breast Cancer Prevention Strategy
- Bi-allelic Inactivation Common in BRCA1 and BRCA Breast Cancers
- In HER2+ Breast Cancer, Higher TIL Levels Associated With Improved OS
- High Immune Gene Expression Linked to Better Prognosis in TNBC
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