Pediatric Cancer

AYA Cancer Survivors More Likely to Have Mental Distress Than Healthy Individuals

AYA Cancer Survivors More Likely to Have Mental Distress Than Healthy Individuals

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Using the Kessler nonspecific mental/psychological distress scale, investigators examined whether AYA cancer survivor experienced greater mental distress and assessed their access to mental health care.

Pediatric Patients Continue to Experience High-Intensity EOL Care

Pediatric Patients Continue to Experience High-Intensity EOL Care

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Studies of end-of-life (EOL) care for pediatric patients have been limited to single institutions or lacked detailed clinical data. Therefore, researchers conducted a retrospective cohort study to examine predictor of, and trends in, high-intensity EOL care in this patient population.

Postop RT Deferral Associated With Worse Survival in Children With Medulloblastoma

Postop RT Deferral Associated With Worse Survival in Children With Medulloblastoma

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Despite the use of adjuvant chemotherapy, deferral of postoperative radiotherapy is associated with worse survival in pediatric patients with medulloblastoma.

Experimental Targeted Therapy Succeeds in Rare Pediatric Cancer

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The experimental treatment LOXO-101 led to remarkable improvement for a 20-month-old girl whose rare pediatric cancer did not respond to surgery or chemotherapy.

Predicting Seizure Incidence and Frequency in Survivors of Pediatric Brain Tumors

Predicting Seizure Incidence and Frequency in Survivors of Pediatric Brain Tumors

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Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center sought to assess the effects of treatment for brain tumors in children over 10 years of follow-up.

Genetic landscape can impact treatment for children with rare, aggressive cancer

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Precision medicine may help doctors determine the best treatment options for children with rare, aggressive, and advanced cancer. Information from a patient's entire genome helped personalize treatment options for children with cancer, according to a new study.

Some Pediatric Patients With Wilms' Tumor Can Avoid Doxorubicin

Some Pediatric Patients With Wilms' Tumor Can Avoid Doxorubicin

Children with Wilm's tumor who are at low risk for relapse can be given less intensive treatment by omitting doxorubicin from the treatment regimen.

Improvements to mental health services for parents who lost a child to cancer are needed

Improvements to mental health services for parents who lost a child to cancer are needed

Parents of children with cancer appear to need, want, and often access bereavement mental health services after the death of their child.

Adapting Pediatric Cancer Treatments to Spur Early Detection and Reduce Late Effects

Adapting Pediatric Cancer Treatments to Spur Early Detection and Reduce Late Effects

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Modifying pediatric cancer treatments may reduce occurrence of late effects and promoting early detection, indicated data from a 5-year analysis of childhood cancers survivors presented at ASCO 2015.

Pediatric patients treated with proton therapy on the rise

Pediatric patients treated with proton therapy on the rise

There has been a 36% increase in the number of pediatric patients who are being treated with proton therapy for cancer.

Possible treatment identified for lethal pediatric brain cancer

Possible treatment identified for lethal pediatric brain cancer

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Gene-regulating drugs may be effective at treating diffuse intrinsic pontine gliomas (DIPG), research indicates.

Childhood cancer treatments may increase obesity risk later

Childhood cancer treatments may increase obesity risk later

Certain treatments used to treat children with cancer may increase their risk for obesity later in life.

Higher-than-expected pediatric cancer rates identified in two Florida areas

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A series of statistical analyses have identified both the Miami metro area and an area west of the Everglades as having unusually high rates of pediatric cancers.

Children with advanced cancer experience high symptom distress

Children with advanced cancer experience high symptom distress

A recent study examined symptom distress in children living with advanced cancer, and found that a majority experience high symptom distress.

Model Details Challenges of Educating Staff in Pediatric, Adult Oncology Patient Care

Model Details Challenges of Educating Staff in Pediatric, Adult Oncology Patient Care

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A model was created to address the challenges of educating staff that care for both adult and pediatric patients.

Program Improves Transitioning Young Cancer Survivors to Adult Survivorship Care

Program Improves Transitioning Young Cancer Survivors to Adult Survivorship Care

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A program improves the transition from pediatric to adult survivorship care has had a 100% increase in referrals.

Treatment guidelines for pediatric Hodgkin lymphoma issued by the International Lymphoma Radiation Oncology Group (ILROG)

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The International Lymphoma Radiation Oncology Group (ILROG) has issued a guideline outlining use of 3-D computed tomography (CT)-based radiation therapy planning.

Prevalence of childhood cancer survivors increasing

Prevalence of childhood cancer survivors increasing

Prevalence of childhood cancer survivors is increasing, and those who survived at least 5 years beyond diagnosis have at least one comorbidity.

Breastfeeding may decrease risk of pediatric acute lymphoblastic leukemia

Breastfeeding may decrease risk of pediatric acute lymphoblastic leukemia

Breastfeeding a child may reduce that child's risk of developing pediatric acute lymphoblastic leukemia (ALL).

Gene regulatory path revealed as target for therapy of aggressive pediatric brain cancer

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Working with cells taken from children with a rare form of brain cancer, scientists have identified a genetic pathway that may spur cancer cell growth and resistance to anticancer treatment.

Sun damage predisposes pediatric patients to melanoma

Sun damage predisposes pediatric patients to melanoma

Melanoma in some adolescent and adult patients involve many of the same genetic mutations and would likely respond to the same treatment.

Adult survivors of pediatric cancer who underwent brain irradiation at risk for hormone deficiencies

Adult survivors of pediatric cancer who underwent brain irradiation at risk for hormone deficiencies

Adult survivors of pediatric cancer are at risk for developing pituitary hormone deficiencies that may worsen their health and quality of life.

Group finds new method for identifying most aggressive childhood cancers

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A new method involving the study of genetic micro-variation, rather than the presence of individual mutations, could help identify malignant tumors in children.

Alternative DNA repair mechanism could provide better treatment for neuroblastoma in children

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A promising target for developing new therapies for children with high-risk neuroblastoma has been found.

Audio therapy for pediatric postoperative pain

Audio therapy for pediatric postoperative pain

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Listening to music or audiobooks has a profound impact on postoperative pain perception in children. The benefit is increased when the patients are allowed to choose their own music or stories.

Potential therapy found for incurable pediatric brain tumor

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Scientists have developed a new potential drug therapy for a rare, incurable pediatric brain tumor by targeting a genetic mutation found in children with the cancer.

Insufficient fluconazole levels in pediatric patients with cancer treated for invasive candidiasis

Insufficient fluconazole levels in pediatric patients with cancer treated for invasive candidiasis

Fluconazole concentration in pediatric patients with cancer and invasive candidiasis is not sufficient for treatment.

Experimental breast cancer drug holds promise in combination therapy for Ewing sarcoma

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When Ewing sarcoma tumors in mice were treated with combination therapy that included drugs from a family of agents developed to fight breast cancer, the tumors disappeared in a majority of test cases.

For pediatric patients with acute lymphoblastic leukemia (ALL), obesity increases risk of persistent disease

For pediatric patients with acute lymphoblastic leukemia (ALL), obesity increases risk of persistent disease

Obese pediatric patients with acute lymphoblastic leukemia (ALL) are more likely to have minimal residual disease.

Weekend hospitalization linked to longer stays for pediatric patients with leukemia

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Weekend hospital admission for pediatric patients with newly diagnosed leukemia is associated with a longer length of stay, slightly longer wait to start chemotherapy, and higher risk for respiratory failure.

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