Patient Outcomes

Postoperative radiation therapy improves overall survival in resected NSCLC

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Patients with non-small lung cancer (NSCLC) that received postoperative radiation therapy (PORT) lived an average of 4 months longer, when compared with patients who had the same disease progression and treatment criteria.

Stereotactic body radiotherapy (SBRT) effective for inoperable early stage lung cancer

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Excellent long-term, local control for medically inoperable, early stage lung cancer patients is possible, according to a review of data from an institutional patient registry on stereotactic body radiotherapy (SBRT).

Combination treatment for metastatic melanoma results in longer overall survival

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Treatment with a combination of the drugs sargramostim plus ipilimumab, rather than ipilimumab alone, yielded longer overall survival and lower toxicity for patients with metastatic melanoma.

Cellular evidence for mind-body connection in breast cancer survivors

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Researchers have demonstrated that employing mindfulness meditation or being a member of a support group has a positive physical impact at the cellular level in breast cancer survivors.

Risk prediction improved by new classification in chronic lymphocytic leukemia

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A new correlation discovered between specific molecular disease features and subgroups of patients with different prognoses could make identification of chronic lymphocytic leukemia (CLL) prognosis at the time of diagnosis possible.

Quality of biopsy directly linked to survival in patients with bladder cancer

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Researchers have demonstrated for the first time that the quality level of diagnostic staging using biopsy in patients with bladder cancer is directly linked with their survival.

Resection for lung cancer in the elderly: Lobectomy better than sublobar resection

Resection for lung cancer in the elderly: Lobectomy better than sublobar resection

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Significant advances have been made in screening for lung cancer and in targeting those patients who will benefit most from it. This study examines the impact of screening and treatment modalities on elderly patients.

Postsurgery readmission rates questioned as a quality measure in colorectal cancer care

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Hospital readmission rates after colorectal cancer surgery showed little variation when the data was adjusted to account for patient characteristics, coexisting illnesses, and operation types.

Breast cancer tumor response to neoadjuvant chemotherapy (NAC) measured

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Diffuse optical spectroscopic tomographic imaging (DOST) may be useful in predicting which patients will best respond to chemotherapy used to reduce breast cancer tumors before surgery, according to a new study.

Early palliative care can cut hospital readmissions for cancer patients

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A new, collaborative model in cancer care aims to reduce the rates at which patients go to intensive care or are readmitted to the hospital after discharge.

Trastuzumab shows benefit years after treatment for HER2+ breast cancer

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The addition of trastuzumab to chemotherapy significantly improved the overall and disease-free survival of women with early stage HER2-positive breast cancer.

Innovative program helps combat catheter-associated urinary tract infections (CAUTI)

Innovative program helps combat catheter-associated urinary tract infections (CAUTI)

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Oncology nurses at a New York cancer center successfully reduced the rate of CAUTIs at their facility to zero with a novel program that gives nurses autonomy in making care decisions for patients with urinary catheters.

Survival comparable after radiation therapy for tumors in left or right breast

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Location of a breast cancer tumor, on the left or right side, does not impact overall survival in patients treated with breast-conserving surgery and adjuvant external beam radiation therapy.

3-D printed facial prosthesis offers new hope for eye cancer patients after surgery

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By utilizing both facial scanning software and 3-D printing, researchers have developed an inexpensive way to make facial prostheses for patients with eye cancer.

Treatments and survival benefits compared for early stage lung cancer

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Removal of an entire lung lobe may offer patients with early stage lung cancer better overall survival compared with a partial resection.

Cancer prehabilitation: One step toward improved outcomes

Cancer prehabilitation: One step toward improved outcomes

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As cancer care evolves toward anticipatory rather than reactionary care, oncology nurses should consider developing important new skills.

Advances in creating treatment for common childhood blood cancer

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A new drug in development may offer analternative to standard chemotherapy for patient with T-cell acute lymphoblastic leukemia, according to new research.

Subsidies help breast cancer patients adhere to hormone therapy

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A federal prescription-subsidy program for low-income Medicare recipients has increased adherence to hormone therapy to prevent breast cancer recurrence after surgery, according to recent data.

Poor staging linked to mortality in bladder cancer

Poor staging linked to mortality in bladder cancer

In cases of bladder cancer, omission of muscle in specimen or its mention in pathology report is linked to increased mortality.

Dramatic response and resistance to cancer drug traced to unsuspected mutations

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Examination of the DNA of a thyroid cancer survivor has revealed details about resistance to the drug everolimus, according to researchers.

New treatment for retinoblastoma expected to save more eyes from cancer

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A new technique to treat retinoblastoma may help prevent eye loss, blindness, or death in children with advanced forms of the disease.

Achieving clinical trial participation through cooperative networks

Achieving clinical trial participation through cooperative networks

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Clinical trials could benefit from a greater number of participants with a dedicated cooperative network to support rural community cancer centers.

Lung cancer can stay hidden for 20+ years

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Lung cancer can remain dormant in the body for many years before emerging in an aggressive form, according to new research.

Improved tyrosine kinase inhibitor (TKI) selectively activates in tumor tissue, minimizing side effects in patients

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A new strategy developed by an interdisciplinary team of researchers aims to reduce the side effects connected to use of tyrosine kinase inhibitors (TKIs).

Immunotherapy added to radiotherapy may help overcome resistance to treatments

Immunotherapy added to radiotherapy may help overcome resistance to treatments

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Coupling immunotherapy to radiotherapy treatment could help prevent cancers from becoming resistant to treatment, according to a new study.

Current therapy for hypothyroidism endorsed by new guidelines

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A recent review has found insufficient consistent data exist to recommend a change in use of levothyroxine as the only drug needed to treat hypothyroidism.

Importance of sequence in chemotherapy administration

Importance of sequence in chemotherapy administration

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Is sequencing important when administering chemotherapy on the same day?

Nearly 5 percent of cancer patients die a month after surgery

Nearly 5 percent of cancer patients die a month after surgery

In a study of more than 1.1 million cancer patients who had surgery, almost 5 percent died within one month of their operation. Lack of access to quality care a major factor in these deaths, researchers say.

High-dose radiotherapy doesn't offer survival benefit in mesothelioma

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Treatnent with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to phase II trial data.

Afatinib improves progression-free survival in head and neck cancer

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After failure of platinum-based chemotherapy, the tyrosine kinase inhibitor (TKI) afatinib significantly improved progression-free survival in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

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