Patient Outcomes

Y-90 radioembolization: A new treatment for hepatic metastases from breast cancer

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Yttrium-90 radioembolization is a minimally invasive treatment that may slow disease progression in breast cancer that has metastasized to the liver.

Doxorubicin-ifosfamide combo improves progression-free survival in soft-tissue sarcoma

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A new European study does not support administration of intensified doxorubicin and ifosfamide for palliation of advanced soft tissue sarcoma.

New gene implicated in progression and recurrence of triple-negative breast cancer

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A gene not previously associated with breast cancer appears to play a pivotal role in the growth and progression of triple-negative breast cancer.

Faster cognitive decline lowers cancer mortality risk

Faster cognitive decline lowers cancer mortality risk

Elderly with faster cognitive decline were found to have lower risk of cancer mortality, according to research.

Potentially curative surgery for localized pancreatic cancer is underutilized

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Surgical resection of early-stage pancreatic tumors has the potential to cure patients with this deadly disease but continues to be underutilized, according to a new national analysis.

Mindfulness-based meditation may help teenagers cope with cancer

Mindfulness-based meditation may help teenagers cope with cancer

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Mindfulness-based meditation could lessen some symptoms associated with cancer in teens, including depression and sleep quality in girls, according to the results of a preliminary study.

Exceptional response to everolimus is reported in patient with bladder cancer patient

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A patient with advanced bladder cancer experienced a complete response to the drug combination everolimus and pazopanib in a phase 1 clinical trial. Genomic profiling revealed information that could help identify other patients who may respond to everolimus and pazopanib.

Steep drop in colon cancer incidence seen among older Americans

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Colon cancer incidence rates have dropped 30% in the United States in the last 10 years among adults 50 years and older, the largest decrease in people older than 65 years.

High adenoma detection rate lowers interval colorectal cancer risk

High adenoma detection rate lowers interval colorectal cancer risk

Adenoma detection rate is inversely associated with risk of interval colorectal cancer.

Radiotherapy after mastectomy improves outcomes for patients with up to three positive lymph nodes

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Women whose breast cancer has spread to just a few axial lymph nodes are less likely to have their disease recur or to die from it if they have radiotherapy after mastectomy.

Chemotherapy-free treatment a possibility for leukemia/lymphoma

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Patients with terminal forms of leukemia and lymphoma who have run out of treatment options could soon benefit from a new drug, which not only puts an end to chemotherapy and has virtually no side effects.

Early relapse risk is higher when omitting radiotherapy in PET-negative early Hodgkin lymphoma

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The risk of early relapse is increased when radiotherapy is omitted in patients with stage I/II Hodgkin lymphoma whose PET scan findings are negative, according to an interim trial analysis.

New approach reduces opioid painkiller use after breast reconstruction surgery

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A new approach to breast reconstruction surgery aimed at helping patients' bodies get back to normal more quickly cut their postoperative painkiller use in half and reduced hospital stay, a new study found.

Long-term quality of life is good after esophagectomy and gastric pull-up

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Long-term survivors can enjoy a satisfying meal and good quality of life after esophagectomy with gastric pull-up, according to a new study.

Molecular test prompts changes in prostate cancer treatment plans

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The PROCEDE 500 study demonstrated that 65% of physicians changed their original treatment plans for men with prostate cancer based on results from the Prolaris test.

Bone turnover markers predict prostate cancer outcomes

Bone turnover markers predict prostate cancer outcomes

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Biomarkers for the formation and resorption of bone predict outcomes for men with castration-resistant prostate cancer (CRPC).

Younger men benefit most from surgery for localized prostate cancer

Younger men benefit most from surgery for localized prostate cancer

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A new study found substantial long-term reduction in mortality for men with localized prostate cancer who undergo a radical prostatectomy.

Key protein identified that helps prevent lung cancer tumors from being destroyed

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Eliminating the protein Mcl-1 could make radiation and chemotherapies more effective in treating the most common and deadly of all cancers, non-small cell lung cancer.

Investigational drug may increase survival of advanced melanoma

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An experimental drug aimed at restoring the immune system's ability to spot and attack cancer halted cancer progression or shrank tumors in patients with advanced melanoma, according to an early-phase clinical trial.

Earlier palliative care improves quality of life

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Earlier care improves quality of life and patient satisfaction, according to the results of the first clinical study to assess the impact of providing early outpatient palliative care versus standard oncology care.

Reducing radiation therapy dose to bilateral submandibular lymph nodes improves salivary function

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For head and neck cancer patients undergoing radiation therapy, a reduction in the amount of radiation treatment volume to the submandibular (level IB) lymph nodes resulted in better patient-reported salivary function.

No survival improvement from bevacizumab for patients with newly diagnosed glioblastoma

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Adding bevacizumab (Avastin) to standard chemotherapy and radiation treatment does not improve survival for patients with newly diagnosed glioblastoma, an often deadly brain cancer, researchers reported.

Favorable outcomes from unilateral radiation therapy for advanced tonsil cancer

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Limiting radiation therapy to lymph nodes on one side of the neck for advanced tonsil cancer resulted in good local regional control and no cancer recurrence on the untreated side, according to new research presented at the 2014 Multidisciplinary Head and Neck Cancer Symposium in Scottsdale, Arizona.

Hypnosis therapy decreases fatigue in breast cancer patients

Hypnosis therapy decreases fatigue in breast cancer patients

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Breast cancer patients receiving radiotherapy showed decreased fatigue as a result of cognitive behavioral therapy plus hypnosis, according to a new study.

Feasible and safe to limit radiation to major salivary glands in HNCs

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Avoiding the contralateral submandibular gland during radiation therapy is feasible and safe with advanced stage, node-positive head and neck cancers and base of tongue lesions, according to new research.

Patients with oropharyngeal cancer report quality of voice and speech affected posttreatment

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Oropharyngeal cancer patients treated with combined chemotherapy and radiation therapy reported a decrease in their voice and speech quality for up to a year after the completion of treatment.

HPV status and intra-tumor heterogeneity mark improved patient outcomes in HNSCC

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Combining Mutant-Allele Tumor Heterogeneity (MATH) as a biomarker with a patient's HPV status provides an effective indicator of improved patient outcome.

Genetically modified T cells eradicate advanced leukemia

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The largest clinical study ever conducted to date of patients with advanced leukemia found that 88% achieved complete remission after being treated with genetically modified versions of their own immune cells.

New first-line option for follicular lymphoma explored

The use of radioimmunotherapy treatment in patients with newly diagnosed follicular lymphoma has been investigated in a new study.

Secondary thyroid cancer more deadly than primary malignancy in younger patients

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A new analysis has found that adolescents and young adults who develop thyroid cancer as a secondary cancer have a significantly greater risk of dying than those with primary thyroid cancer.

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