Patient Outcomes

Cancer treatment impact on cardiovascular risk factors

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The oncology community is well aware that cancer therapy is fraught with increased risk of cardiovascular disease (CVD). Of the almost 12 million cancer survivors in the United States, many are more likely to die of CVD...

High costs of leukemia may be harming patients

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The increasing cost of treatments for chronic myeloid leukemia in the United States has reached unsustainably high levels and may be leaving many patients under- or untreated because they cannot afford care.

Frail, elderly patients may not benefit from surgery for nonfatal skin cancers

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A new study focused on the vexing problem of how best to handle skin cancers among frail, elderly patients.

Quantifying heterogeneity in breast cancer

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Later-stage breast cancers tend to have more mutations and are more heterogeneous than early-stage cancers. Now, new findings demonstrate that heterogeneity is prevalent even within legions of DCIS.

Potential new prognostic tool found in genes common to tobacco-associated cancers

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Though researchers have explored which genes are mutated in each type of tobacco-associated cancer, until now no one had thought to look across these types for common genes that might predict patient outcomes.

Biomarker may help identify neuroblastomas vulnerable to a novel class of drugs

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An irregularity within many neuroblastoma cells may indicate whether a neuroblastoma tumor is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors.

Genetic mutation is associated with increased risk of death for patients with PTC

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Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer. However, how to use this information to manage mortality risk is unclear.

Canine osteosarcoma samples identify drivers of metastasis in pediatric bone cancer

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Researchers presenting at the American Association for Cancer Research Annual Meeting 2013 used easily available canine osteosarcoma samples to discover a novel protein that governs metastasis and chemoresistance in pediatric osteosarcoma.

Prostate cancer survival may be compromised by on-and-off treatment approach

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Taking a break from hormone-blocking prostate cancer treatments once the cancer seems to be stabilized is not equivalent to continuing therapy, a new large-scale international study finds.

Radiotherapy side effects: Understanding pelvic radiation disease

Radiotherapy side effects: Understanding pelvic radiation disease By

The key to managing this late effect is patient education because it can manifest long after patients complete radiotherapy.

Patient navigator: A role for nurses that goes beyond clinical care

Patient navigator: A role for nurses that goes beyond clinical care

Cancer care entails a confusing labyrinth of screenings, tests, and treatments. This emerging role for nurses is becoming increasingly vital to achieve ideal patient outcomes.

Personalized brain mapping technique preserves function after brain tumor surgery

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The imaging technique of DTI allows neurosurgeons to visualize important pathways in the brain. This allows them to better adapt brain tumor surgeries and preserve language, visual function, and motor function while removing cancerous tissue.

Lung cancer may metastasize in many directions

A mathematical model indicates that lung cancer probably metastasizes in more than one direction at a time, contradicting the traditional view.

African Americans experience longer delay between prostate cancer diagnosis and treatment

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African American men on average wait a week longer than their Caucasian counterparts between the initial diagnosis of prostate cancer and treatment, according to a new study.

Findings of genetic alterations in bladder cancer could improve screening and treatment

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A new analysis has found that genetic alterations in a particular cellular pathway are linked to bladder cancer risk, recurrence, disease progression, and patient survival. The findings could help improve bladder cancer screening and treatment.

Medicare spending is not linked to survival differences in advanced cancer

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Substantial regional variation in Medicare spending for patients with advanced cancer is not linked to differences in survival, according to a new study.

New reconstructive procedure repairs nose after skin cancer in just one step

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A new reconstruction technique uses cartilage from behind the ear and skin from the shoulder to repair the nose in one step after skin cancer.

Low T3 syndrome predicts unfavorable outcomes in surgical patients with brain tumor

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Among patients undergoing surgery for a brain tumor, low T3 (triiodothyronine) syndrome has been found to be predictive of unfavorable clinical outcomes and depressive symptoms.

Surgery is superior to radiotherapy in men with localized prostate cancer

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Surgery offers a better survival benefit for men with localized prostate cancer, according to a large observational study.

Where a patient is treated affects cancer survival

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The study found that despite the improved survival at high-volume hospitals, the proportion of patients who received multimodality therapy was similar, as it was received by 78% of patients at low-volume hospitals and 79% at high-volume hospitals.

PTSD occurs in nearly 1 in 4 women with newly diagnosed breast cancer

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Twenty-three percent of women with newly diagnosed breast cancer reported symptoms consistent with post-traumatic stress disorder shortly after diagnosis. The risk was increased among black and Asian women by more than 50%.

Breast reconstruction outcomes similar with two shapes of implants

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For women undergoing breast reconstruction with implants, most patient-reported outcomes are similar with two different types of silicone gel-filled implants.

Stem cells and specially generated T cells from same donor improve leukemia survival

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Patients with high-risk or relapsed leukemia have been successfully treated with post-stem cell transplantation infusions of large numbers of donor T cells specific for an antileukemic antigen key to prolonging survival, both from the same matched donors.

'Quality-of-life' therapy improves health during cancer treatment

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Therapy to ease stress, fatigue, and other quality-of-life issues significantly improves patients' sense of well-being during cancer treatment, according to new research from a randomized trial.

Tool tested to screen cancer patients for malnutrition

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Researchers have found that a shorter version of a commonly used nutrition-assessment tool effectively helps cancer patients maintain proper nutrition and can potentially improve their outcomes.

5-ALA fluorescence guide improves resection of glioblastoma multiforme

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Fluorescence form 5-aminolevulinic acid (5-ALA) has been used to guide resection of recurrent GBM. Before surgery, the patient ingests 5-ALA, then the tumor cells fluoresce intraoperatively in response to certain wavelengths of light.

Serious autologous breast reconstruction complications are few, and vary by procedure

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Breast cancer patients who undergo a mastectomy followed by breast reconstruction using a transplanted flap of their own tissue have a low rate of early postoperative complications. However, a new study found that their risk varies by the type of flap procedure they undergo.

Training in problem solving helps mothers cope with child's cancer diagnosis

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The benefits of training in problem-solving skills goes beyond teaching parents to navigate the complex systems that accompany a child's diagnosis of cancer. It also leads to a durable reduction in mothers' levels of anxiety and symptoms of posttraumatic stress, and improves overall coping with a child's illness.

Assessing and treating 
radiotherapy-associated 
diarrhea

Assessing and treating 
radiotherapy-associated 
diarrhea By

A common side effect of cancer treatment, including radiotherapy, is diarrhea. Treatment is based on its cause and severity.

Study results support patient concerns about a controversial side effect of therapy

Study results support patient concerns about a controversial side effect of therapy By

A posttreatment assessment of men who underwent treatment for prostate cancer revealed a side effect that has a significant impact on patients.

Regimen and Drug Listings

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