Pancreatic Cancer section

Pancreatic Cancer News & Features

Protein inhibition opens door for pancreatic cancer treatment

The protein galectin-1 has been identified as a possible therapeutic target for pancreatic cancer; new research has demonstrated that inhibiting this protein in mice with pancreatic cancer increased survival by 20%.

Novel cellular mechanism for pancreatic cancer drug resistance identified

Pancreatic cancers dependent on signaling from a mutant Kras gene for their growth and progression in the laboratory are able to switch to Yap1, another oncogene, if Kras is blocked.

Nanoliposome formulation improves drug delivery and survival in metastatic pancreatic cancer

The addition of MM-398, a novel nanoliposome formulation of irinotecan, to standard treatment improves survival for metastatic pancreatic cancer patients who have already received gemcitabine.

New vaccine reprograms pancreatic cancer cells to respond to immunotherapy

New vaccine reprograms pancreatic cancer cells to respond to immunotherapy

A new vaccine triggered the growth of immune cell nodules within pancreatic tumors, reprogramming these intractable cancers and making them vulnerable to immune-based therapies.

Direct injection treatment of pancreatic cancer shows encouraging results

Direct injection treatment of pancreatic cancer shows encouraging results

Results of a phase I clinical trial of a vaccine therapy for pancreatic cancer indicate the treatment is well tolerated; in addition, it suggests that the vaccine stabilizes the disease for a period of time.

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