Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

By identifying incidence, prevalence, and risk factors for colorectal and pancreatic cancer in our communities, nurse navigators can develop screening and prevention programs to better serve these populations.

Genome-Informed Treatment Improves Survival in Pancreatic Cancer

Genome-Informed Treatment Improves Survival in Pancreatic Cancer

Precision Medicine Improves Pancreatic Cancer Treatment

Cisplatin Plus Standard-of-Care Regimen Reduced Tumors in Advanced Pancreatic Cancer

Cisplatin Plus Standard-of-Care Regimen Reduced Tumors in Advanced Pancreatic Cancer

Cisplatin plus standard-of-care gemcitabine/nab-paclitaxel improved tumor shrinkage in patients with metastatic pancreatic cancer, according to a study by the HonorHealth Research Institute and the Translational Genomics Research Institute.

Biopolymer Delivery of Synergistic Immunotherapy Could Improve Efficacy

Biopolymer Delivery of Synergistic Immunotherapy Could Improve Efficacy

Biopolymer codelivery of CAR T cells and stimulator of IFN genes directly to the surface of solid tumors more effectively reduced tumor size.

Onset or Rapid Worsening of Diabetes May Indicate Pancreatic Cancer

Onset or Rapid Worsening of Diabetes May Indicate Pancreatic Cancer

An investigation into whether onset or worsening of diabetes causes pancreatic cancer or vice versa was presented at the 2017 European Cancer Congress.

Postoperative Gemcitabine Plus Capecitabine: A New Standard of Care for Pancreatic Cancer

Postoperative Gemcitabine Plus Capecitabine: A New Standard of Care for Pancreatic Cancer

Use of Adjuvant gemcitabine plus capecitabine for patients with pancreatic cancer who have undergone tumor resection resulted in a modest increase short-term survival.

Study Raises Questions About PDX1 as a Potential Pancreatic Cancer Target

Study Raises Questions About PDX1 as a Potential Pancreatic Cancer Target

PDX1 appears to have distinct roles at different stages of pancreatic cancer development.

Selumetinib + MK-2206 Fails to Improve Survival vs mFOLFOX in Pancreatic Cancer

Selumetinib + MK-2206 Fails to Improve Survival vs mFOLFOX in Pancreatic Cancer

Seluminitinib in combination with an AKT inhibitor did not improve survival compared with modified FOLFOX in previously treated metastatic pancreatic cancer.

Favorable Perioperative Outcomes After Resection of Borderline Resectable Pancreatic Cancer Treated With Neoadjuvant Stereotactic Radiation and Chemotherapy Compared with Upfront Pancreatectomy for Resectable Cancer

Favorable Perioperative Outcomes After Resection of Borderline Resectable Pancreatic Cancer Treated With Neoadjuvant Stereotactic Radiation and Chemotherapy Compared with Upfront Pancreatectomy for Resectable Cancer

[Journal of Gastrointestinal Oncology] This research examines outcomes related to the use of neoadjuvant multi-agent chemotherapy and stereotactic body radiation therapy (SBRT) in borderline resectable pancreatic cancer (BRPC) or locally advanced pancreatic cancer (LAPC) patients.

How Does Obesity Influence Pancreatic Cancer Development and Treatment?

How Does Obesity Influence Pancreatic Cancer Development and Treatment?

Research findings reveal the mechanism by which obesity increases inflammation and desmoplasia in the most frequent type of pancreatic cancer, using mouse models and human tissue samples.

Systematic Palliative Care Provides Greater Improvement in Quality of Life for Patients with Pancreatic Cancer

Systematic Palliative Care Provides Greater Improvement in Quality of Life for Patients with Pancreatic Cancer

Quality of life is significantly improved for patients with pancreatic cancer when systematic palliative care is administered vs on-demand palliative care.

Metastatic Ability May Precede Tumor Formation in Pancreatic Cancer

Metastatic Ability May Precede Tumor Formation in Pancreatic Cancer

Metastatic capabilities of pancreatic cancer might arise before tumors even form. Metastasis and advanced stage of disease at diagnosis are attributed to low survival rates for pancreatic cancer.

Novel Approach Uses Ultrasound to Enhance Efficacy of Chemotherapy in Pancreatic Cancer

Novel Approach Uses Ultrasound to Enhance Efficacy of Chemotherapy in Pancreatic Cancer

Combining a laboratory ultrasound technique called sonoporation with the commercially available chemotherapy compound gemcitabine increases the porosity of pancreatic cells with microbubbles and helps get the drug into cancer cells.

Chemotherapy and Radiation Prior to Surgery Improves Outcomes in Patients With Pancreatic Cancer

Chemotherapy and Radiation Prior to Surgery Improves Outcomes in Patients With Pancreatic Cancer

Despite the increased risk, patients whose pancreatic cancer tumor has grown to encompass critical blood vessels can be candidates for surgery. Data on efforts to fine-tune a protocol for these patients were presented at the SSAT 57th Annual Meeting.

Adjuvant Gemcitabine/Capecitabine: New Standard of Care for Resected Pancreatic Cancer

Adjuvant Gemcitabine/Capecitabine: New Standard of Care for Resected Pancreatic Cancer

Adjuvant gemcitabine plus capecitabine significantly improved overall survival compared with gemcitabine monotherapy in patients with pancreatic ductal adenocarcinoma, according to results of the ESPAC-4 trial presented at the ASCO 2016 Annual Meeting.

Chemoradiotherapy Showed No Survival Benefit Over Chemotherapy in Locally Advanced Pancreatic Cancer

Researchers discovered no survival benefit of chemoradiotherapy over chemotherapy in treating locally advanced pancreatic cancer in the LAP01 Randomized Clinical Trial.

Barriers to Understanding Pancreatic Cancer Can Be Overcome With Improvements to Online Health Information

Barriers to Understanding Pancreatic Cancer Can Be Overcome With Improvements to Online Health Information

Available information on pancreatic cancer was written at too high a level and contained inaccuracies regarding alternative therapies, a recent study has shown.

Molecular profiling of a case of advanced pancreatic cancer identifies an active and tolerable combination of targeted therapy with backbone chemotherapy

Molecular profiling of a case of advanced pancreatic cancer identifies an active and tolerable combination of targeted therapy with backbone chemotherapy

[Journal of Gastrointestinal Oncology] This research reviews the case history of a patient with stage IVB pancreatic adenocarcinoma initially treated with gemcitabine and erlotinib who stopped therapy after 3 months without achieving a response and was switched to a different and effective combination strategy.

New Mechanism to Target RAS Genes Identified

New Mechanism to Target RAS Genes Identified

A small molecule that inhibits RAS protein interactions offers hope for targeting this elusive protein. It is one of the most sought-after cancer targets for drug developers, but the mutant RAS protein lacks drug-binding pockets.

Readability of Online Pancreatic Cancer Info Varies

Readability of Online Pancreatic Cancer Info Varies

Lowest accuracy scores for alternative tx websites; websites with higher accuracy more difficult to read

Targeting Drugs to Pancreatic Cancer Through Implantable Device

New research indicates a far greater efficacy in pancreatic cancer drug therapy delivered via implantable device than via IV.

Immune-stimulating Drug and Chemotherapy Show Early Promise for Pancreatic Cancer

An experimental therapy looks to hold promise for tumor control treatment in pancreatic adenocarcinoma.

AACR: Oral Bacteria Tied to Pancreatic Cancer Risk

AACR: Oral Bacteria Tied to Pancreatic Cancer Risk

Two strains of oral bacteria -- P. gingivalis and A. actinomycetemcomitans -- have been linked to higher risk of pancreatic cancer.

Experimental Immune Therapy Tears Down Protective Microenvironment of Pancreatic Cancer Tumors

Experimental Immune Therapy Tears Down Protective Microenvironment of Pancreatic Cancer Tumors

An experimental immune therapy can re-educate macrophages to tear down the scaffolding that surrounds and protects pancreatic cancer from chemotherapy.

Adjuvant Chemotherapy More Effective in Reducing Distant Pancreatic Cancer Metastasis

Adding radiotherapy to chemotherapy and surgery reduced the number of local disease recurrences but did not affect distant recurrences or survival.

Researchers Believe Pancreatic Cancer Is Four Separate Diseases

Researchers Believe Pancreatic Cancer Is Four Separate Diseases

Researchers identified four classes of genetic error that triggered pancreatic tumors and classified pancreatic cancer as four separate diseases.

Neem Tree Extract Demonstrates Anticancer Activity Against Pancreatic Cancer

Neem Tree Extract Demonstrates Anticancer Activity Against Pancreatic Cancer

A natural extract from the neem tree of India is found to have potential as a treatment for pancreatic cancer.

Implantable Device Delivers Anticancer Regimen Directly Into Pancreatic Cancer Tumors

An implantable device allows large doses of highly toxic drugs to be delivered directly to pancreatic tumors while reducing exposure to the toxic side effects in the rest of the body.

Nanoparticle Drug Delivery Aims to Control Pancreatic Tumor and Inhibit Escape Pathways

Use of a nanoparticle to deliver drugs may reduce tumors and suppress metastatic escape. These efforts offer a way to control drug release over space and time while reducing systemic drug exposure and the associated side effects.

CDK4/6 Inhibitors Exploit a Unique Vulnerability in Pancreatic Cancer

CDK4/6 Inhibitors Exploit a Unique Vulnerability in Pancreatic Cancer

The metabolism of pancreatic cancer cells is altered by the anticancer activity of CDK4/6 inhibitors. Researchers hope this biologic vulnerability could be exploited to treat pancreatic cancer.

Adding Leucovorin to S-1 Improves PFS in Advanced Pancreatic Cancer

The addition of leucovorin to S-1 significantly improved progression-free survival compared with S-1 alone in patients with advanced pancreatic cancer who were refractory to gemcitabine.

Family Members of Patients With CUP Are At Increased Risk for Several Types of Cancer

Family members of patients with cancers of unknown primary (CUP) are at higher risk of developing CUP themselves, as well as cancers of the lung, pancreas, and colon and some cancers of the blood.

Portal Vein Blood Leads to Earlier, More Accurate Pancreatic Cancer Diagnosis

Portal Vein Blood Leads to Earlier, More Accurate Pancreatic Cancer Diagnosis

Blood samples collected from the portal vein can tell physicians far more about a patient's pancreatic cancer than peripheral blood collected from a more easily accessed vein in the arm.

Investigational Drug Is Effective Against Debilitating Adverse Effect of Cancer in Preclinical Trials

Investigational Drug Is Effective Against Debilitating Adverse Effect of Cancer in Preclinical Trials

New data describes how an experimental drug can stop the debilitating and life-threatening adverse effect cachexia commonly associated with advanced cancers and restore muscle health.

Blood Sample Offers a New Way of Detecting Cancer

Blood Sample Offers a New Way of Detecting Cancer

RNA test of blood platelets can detect, classify, and pinpoint the location of cancer by analyzing a sample equivalent to 1 drop of blood. Using this new method, researchers were able to identify cancer with 96% accuracy.

Nanoliposomal Irinotecan Extends Survival in Metastatic Pancreatic Cancer

Nanoliposomal Irinotecan Extends Survival in Metastatic Pancreatic Cancer

Nanoliposomal irinotecan in combination with fluorouracil and folinic acid improves survival in patients with pancreatic ductal adenocarcinoma.

Study Findings Explain Why Chemotherapy May be Compromised in Patients With Pancreatic Cancer

Study findings may explain why chemotherapy drugs such as gemcitabine are not effective for many patients with pancreatic cancer, and perhaps point to new approaches to treatment including enhancing gemcitabine's ability to stop tumor growth.

Blood Test Can Guide Treatment Sequencing for Pancreatic Cancer

Blood Test Can Guide Treatment Sequencing for Pancreatic Cancer

A widely available, inexpensive blood test can predict outcomes and guide treatment in pancreatic cancer; however, only 1 in 5 US patients with the disease have the blood test.

Concurrent Radiotherapy With Oral Fluoropyrimidine Versus Gemcitabine in Locally Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis

Concurrent Radiotherapy With Oral Fluoropyrimidine Versus Gemcitabine in Locally Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis

[OncoTargets and Therapy] This research evaluates the efficacy and toxicities of oral FU-based CRT compared with GEM-based CRT for the treatment of locally advanced pancreatic cancer (LAPC).

Studies Demonstrate Clinical Advantages of Proton Therapy

Studies Demonstrate Clinical Advantages of Proton Therapy

The search for evidence to support the growing use of proton therapy for more cancers continues to uncover valuable findings. New data from clinical trials demonstrate the potential advantages of proton therapy over conventional radiation for pancreatic cancer, late-stage non-small cell lung cancer, chordoma, and chondrosarcoma.

FDA Approves New Treatment for Advanced Pancreatic Cancer

FDA Approves New Treatment for Advanced Pancreatic Cancer

A new drug for the treatment of advanced (metastatic) pancreatic cancer received FDA approval.

Two-Drug Combination Shows Promise Against One Type of Pancreatic Cancer

Two-Drug Combination Shows Promise Against One Type of Pancreatic Cancer

Researchers have shown that a certain protein becomes overabundant in pancreatic neuroendocrine tumors, allowing them to thrive. They also found that pairing a synthetic compound with an existing drug provides a more effective anticancer punch than a single drug.

Ablation Modality Significantly Increases Survival in Patients With Pancreatic Cancer

Ablation Modality Significantly Increases Survival in Patients With Pancreatic Cancer

Use of irreversible electroporation (IRE) doubles survival time for patients with locally advanced pancreatic cancer.

Irreversible electroporation may hold promise for pancreatic cancer

Irreversible electroporation may hold promise for pancreatic cancer

Study found IRE procedure improved survival for people with stage III disease.

Researchers identify genes associated with increased survival of pancreatic cancer

Researchers identify genes associated with increased survival of pancreatic cancer

A new set of genes has been identified that can indicate improved survival after surgery for patients with pancreatic cancer. The study also showed that detection of circulating tumor DNA in the blood could provide an early indication of tumor recurrence.

Molecular Partnership With Nerve-Guiding Protein Aids Pancreatic Metastasis

Molecular Partnership With Nerve-Guiding Protein Aids Pancreatic Metastasis

Scientists have identified a molecular partnership in pancreatic cancer cells that might help to explain how the disease metastasizes.

Older, younger patients with metastatic pancreatic cancer have similar survival

Older, younger patients with metastatic pancreatic cancer have similar survival

Older patients metastatic pancreatic cancer are less likely to receive chemotherapy compared with younger patients with metastatic disease.

Chemoradiotherapy improves survival after pancreatic adenocarcinoma resection

Chemoradiotherapy improves survival after pancreatic adenocarcinoma resection

Chemoradiotherapy was independently associated with improved overall survival after the resection of pancreatic adenocarcinoma.

Pain management of pancreatic head adenocarcinomas that are unresectable: Celiac plexus neurolysis and splanchnicectomy

Pain management of pancreatic head adenocarcinomas that are unresectable: Celiac plexus neurolysis and splanchnicectomy

[Journal of Gastrointestinal Oncology] This articles outlines pertinent anatomy, techniques, side effects, complications, and efficacy of interventions for palliation of pain from pancreatic cancer.

Urine test can help pinpoint pancreatic cancer earlier

Urine test can help pinpoint pancreatic cancer earlier

Elevated levels of three proteins were detected in the urine of patients with early-stage pancreatic cancer.

Blood tests advancing in their ability to predict recurrence of pancreatic cancer

Blood tests advancing in their ability to predict recurrence of pancreatic cancer

Results of blood tests to detect DNA shed from tumors were found to predict cancer recurrence far earlier than standard imaging methods.

Biomarker discovery could lead to urine test for early stage pancreatic cancer

Biomarker discovery could lead to urine test for early stage pancreatic cancer

A three-protein signature can identify the most common form of pancreatic cancer at an early stage.

A microRNA as an agent for the treatment of pancreatic cancer

A particular microRNA could prove to be a potent therapeutic agent against pancreatic cancer, according to new research.

Blood particles may aid pancreatic cancer diagnosis

A protein encoded by the gene glypican-1 present on cancer exosomes may be used as part of a potential non-invasive screening tool to detect early pancreatic cancer.

Patients with pancreatic cancer report very high levels of needs

Patients with pancreatic cancer report very high levels of needs

People with pancreatic cancer or ampullary cancer reported very high levels of needs.

Protein may help detect early pancreatic cancer

Protein may help detect early pancreatic cancer

A protein encoded in the glypican-1 (GPC1) gene may allow for a non-invasive screening tool to detect early pancreatic cancer.

Common antibiotic part of a new potential pancreatic cancer therapy

Common antibiotic part of a new potential pancreatic cancer therapy

A common antibiotic, when combined with an experimental drug, may have a role in pancreatic cancer treatment.

Stereotactic Body Radiotherapy may benefit certain patients with pancreatic cancer

Stereotactic Body Radiotherapy may benefit certain patients with pancreatic cancer

Stereotactic body radiotherapy appears to be both effective and safe for treatment of advanced pancreatic cancer tumors.

Sunlight deficiency may increase risk of pancreatic tumors

Sunlight deficiency may increase risk of pancreatic tumors

Individuals who live in regions with low sunlight may have a higher risk of pancreatic cancer, and shortage of vitamin D may be to blame.

Investigational personalized cellular therapy tolerated well by patients

Investigational personalized cellular therapy tolerated well by patients

An early stage trial for mesothelioma and pancreatic and ovarian cancers has explored utilizing a patient's own immune cells, genetically modified to target tumors.

MRI screening program for persons at high risk of pancreatic cancer

A magnetic resonance imaging (MRI)-based screening program for persons at high risk of pancreatic cancer identified pancreatic lesions in 40% of patients, according to an online report.

AACR: Metformin benefit not seen in pancreatic ductal cancer

AACR: Metformin benefit not seen in pancreatic ductal cancer

A new study finds the medication doesn't increase survival rates for patients with pancreatic ductal adenocarcinoma.

Metformin may not increase survival of patients with pancreatic cancer

Metformin may not increase survival of patients with pancreatic cancer

Therapy with metformin use did not improve survival of patients with pancreatic ductal adenocarcinoma (PDAC), according to recent study data.

Statin use inversely linked to risk of pancreatic cancer

Statin use inversely linked to risk of pancreatic cancer

Risk reduction appears sex specific, with significant reduction seen for men, but not women.

MRI could be useful pancreatic cancer screen for high-risk patients

MRI could be useful pancreatic cancer screen for high-risk patients

New research indicates that magnetic resonance imaging (MRI) might have a role in early detection for those at high genetic risk of pancreatic cancer.

Study identifies those at high risk for developing pancreatic cancer

Study identifies those at high risk for developing pancreatic cancer

Researchers developed a profile of the patient who would be at highest risk for developing pancreatic lesions.

Photodynamic therapy for pancreatic cancer made simpler and cheaper

Present barriers for the usual dosimetry accompanying photodynamic therapy (PDT) for late-stage pancreatic cancer can be overcome via clinical technologies.

MRI screening may identify high-risk pancreatic cancer

MRI screening may identify high-risk pancreatic cancer

MRI-based screening may be effective in identifying high-risk pancreatic cancer.

New, less aggressive guidelines issued for mangement of pancreatic cysts

New, less aggressive guidelines issued for mangement of pancreatic cysts

New guidelines for pancreatic cyst management recommend surveillance for low-risk cysts, discontinuation after no change for five years.

Potential treatment for pancreatic cancer could increase life expectancy

Researchers have developed a device that uses electric fields to drive chemotherapy drugs through the protective barrier of tissue and directly into pancreatic tumors, preventing their growth.

New study suggests why pancreatic cancer is so aggressive

New study suggests why pancreatic cancer is so aggressive

New study helps explain why pancreatic cancer is so lethal, with less than one-third of patients surviving even early stage disease.

Potential biomarkers of early pancreatic cancer discovered

Potential biomarkers of early pancreatic cancer discovered

Patients with pancreatic cancer face a poor prognosis, as only approximately 6% of patients survive.

Maximum tolerated doses of gemcitabine

Maximum tolerated doses of gemcitabine

How much more toxicity and myelosuppression has been associated with gemcitabine (Gemzar) when it is infused over periods longer than 30 minutes?

Cancer biopsies found not to promote cancer spread

A recent study may dispel the myth that cancer biopsies have a role in the spreading of cancer in the body.

New tool identifies previously unknown genes that cause pancreatic cancer

New tool identifies previously unknown genes that cause pancreatic cancer

A new technique allows discovery of unknown pancreatic cancer genes previously invisible to standard genetic sequencing.

Managing oral side effects of irinotecan therapy

Managing oral side effects of irinotecan therapy

Is there an effective way to manage the oral side effects of irinotecan therapy?

Chemo- and immunotherapy combination is a promising treatment for pancreatic cancer

Chemo- and immunotherapy combination is a promising treatment for pancreatic cancer

Pancreatic cancer may potentially be safely and effectively treated with immunochemotherapy, according to recent research from a preclinical study.

BRCA-related tumors respond to olaparib

Olaparib, an experimental oral cancer drug, has shown an overall tumor response rate of 26% in advanced cancers associated with BRCA1 and BRCA2 mutations, according to recent research.

MicroRNAs can accurately identify pancreatic cancer

MicroRNAs can accurately identify pancreatic cancer

Increased expression of a microRNA (miRNA) panel seems highly accurate for diagnosis of pancreatic ductal adenocarcinoma (PDAC), according to a study published online.

Factors contributing to pancreatic cancer identified

Factors contributing to pancreatic cancer identified

New research that provides a better understanding of pancreatic cancer may help identify those people at increased risk.

People with a family history of pancreatic cancer at increased risk for developing the disease

People with a family history of pancreatic cancer at increased risk for developing the disease

Patients with a family history of pancreatic cancer may be at an increased risk for developing the disease.

Gene expression patterns revealed in pancreatic circulation tumor cells

An analysis of circulating tumor cells (CTCs) in a pancreatic cancer model identified several different classes of CTCs and found unexpected factors that may prove to be future targets for improved treatment.

An episode of sudden-onset jaundice signaled pancreatic cancer in a healthy man

An episode of sudden-onset jaundice signaled pancreatic cancer in a healthy man

After surviving pancreatic cancer, a patient learns the disease metastasized to his liver. But this patient was not ready to give up. With the support of a liver surgeon, he underwent surgery and beat his disease.

Reconstituting nab-paclitaxel

Reconstituting nab-paclitaxel

Is there a good reason to mix nab-paclitaxel (Abraxane) with warm (not cool) normal saline when reconstituting?

Pancreatic cancer risk not increased with dipeptidyl-peptidase-4 inhibitors (DPP-4i)

Pancreatic cancer risk not increased with dipeptidyl-peptidase-4 inhibitors (DPP-4i)

Findings based on comparison to sulfonylureas and thiazolidinediones

For advanced pancreatic cancer, simtuzumab not significantly more effective than placebo

For advanced pancreatic cancer, simtuzumab not significantly more effective than placebo

Gemcitabine in combination with simtuzumab 200 mg or 700 mg did not significantly increase progression-free survival.

For pancreatic cancer, chokeberry extract may enhance effectiveness of gemcitabine

For pancreatic cancer, chokeberry extract may enhance effectiveness of gemcitabine

Chokeberry, a wild berry, may improve the effectiveness of gemcitabine for the treatment of pancreatic cancer.

Existing drug offers new hope in a subtype of pancreatic cancer

Existing drug offers new hope in a subtype of pancreatic cancer

A new use for an old drug shrinks a particular type of pancreatic cancer and stops it from spreading, according to new research.

Several genetic risk markers for pancreatic cancer are identified

A large DNA analysis of people with and without pancreatic cancer has identified several new genetic markers that signal increased risk of developing the highly lethal disease, reported scientists.

Saltier IV reduces complications from Whipple surgery for pancreatic cancer

Adequate hydration via a saline drip is essential during surgery, but recent reports suggest that getting the balance of salt and water just right could have an important impact on patient recovery.

Combined treatment approach for locally advanced pancreatic cancer aims to identify biomarkers

Investigators are developing a novel, multistep investigational treatment for locally advanced pancreatic cancer, which is complex and difficult to treat.

Protein inhibition opens door for pancreatic cancer treatment

The protein galectin-1 has been identified as a possible therapeutic target for pancreatic cancer; new research has demonstrated that inhibiting this protein in mice with pancreatic cancer increased survival by 20%.

Novel cellular mechanism for pancreatic cancer drug resistance identified

Pancreatic cancers dependent on signaling from a mutant Kras gene for their growth and progression in the laboratory are able to switch to Yap1, another oncogene, if Kras is blocked.

Nanoliposome formulation improves drug delivery and survival in metastatic pancreatic cancer

The addition of MM-398, a novel nanoliposome formulation of irinotecan, to standard treatment improves survival for metastatic pancreatic cancer patients who have already received gemcitabine.

New vaccine reprograms pancreatic cancer cells to respond to immunotherapy

New vaccine reprograms pancreatic cancer cells to respond to immunotherapy

A new vaccine triggered the growth of immune cell nodules within pancreatic tumors, reprogramming these intractable cancers and making them vulnerable to immune-based therapies.

Direct injection treatment of pancreatic cancer shows encouraging results

Direct injection treatment of pancreatic cancer shows encouraging results

Results of a phase I clinical trial of a vaccine therapy for pancreatic cancer indicate the treatment is well tolerated; in addition, it suggests that the vaccine stabilizes the disease for a period of time.

Study finds aspirin may reduce cancer risk, but it's not for everyone

Study finds aspirin may reduce cancer risk, but it's not for everyone

Guidelines from the Fred Hutchinson Cancer Research Center advise that low-dose daily aspirin for prevention of pancreatic cancer may not be for everyone.

Daily aspirin may ward off pancreatic cancer

Daily aspirin may ward off pancreatic cancer

People who take low-dose aspirin for more than 10 years might be reducing their risk for pancreatic cancer, a new study suggests.

Promising results from new therapy for pancreatic cancer

A clinical trial showed that the new drug MM-398, given in combination with 5-flourouracil (5-FU) and leucovorin, produced a significant overall survival rate in patients with advanced pancreatic cancer.

Endoscopic oxygen sensor detects pancreatic cancer and hope for earlier detection

An optical blood oxygen sensor attached to an endoscope is able to identify pancreatic cancer in patients via a simple endoscopic procedure, according to researchers.

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