Pain

Low-Dose Sublingual Fentanyl Safe, Effective in Patients Receiving Lower Opioid Doses

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Sublingual fentanyl is used to manage breakthrough pain in adults with cancer who are already receiving opioid therapy for underlying persistent cancer pain. In this study, researchers evaluated the effect of low doses of sublingual fentanyl in patients who are receiving low opioid doses for background analgesia.

Economic Burden of U.S. Opioid Epidemic is 78.5 Billion Dollars Annually

Economic Burden of U.S. Opioid Epidemic is 78.5 Billion Dollars Annually

Patient abuse of opioids costs the U.S. economy $78.5 billion a year, including the costs of health care, lost productivity, and treatment programs.

Drug-free Methods Effective for Treating Some Pain Conditions

Drug-free Methods Effective for Treating Some Pain Conditions

Approaches such as acupuncture, massage, and tai chi may ease discomfort

Analgesic Effects of Cannabis Is Different Between Men and Women

Analgesic Effects of Cannabis Is Different Between Men and Women

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Pain response—sensitivity and tolerance—after use of active cannabis differs between men and women.

Study Identifies Disparities in Cancer Pain Management

Study Identifies Disparities in Cancer Pain Management

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Cancer survivors who are nonwhite, less educated, older, and/or have comorbidities were less likely to receive adequate cancer pain management.

Massage Therapy Promising for Pain, Anxiety in Patients With Cancer

Massage Therapy Promising for Pain, Anxiety in Patients With Cancer

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Massage therapy may be promising for reducing the intensity/severity of pain, fatigue, and anxiety in patients with cancer.

Use, Outcomes of Urine Drug Tests Among Patients With Advanced Cancer

Use, Outcomes of Urine Drug Tests Among Patients With Advanced Cancer

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Despite the infrequency of urine drug test ordering, greater than half of all urine drug tests results were abnormal among outpatients with advanced cancer.

Methadone May Be Superior to Fentanyl for Neuropathic Pain

Methadone May Be Superior to Fentanyl for Neuropathic Pain

Methadone appears to be superior to fentanyl for the treatment of neuropathic pain in patients with head and neck cancer.

Guidelines Developed to Manage Pain in Cancer Survivors

Guidelines Developed to Manage Pain in Cancer Survivors

Recurrent disease, second malignancy, late-onset treatment effects should be assessed in patients with new pain, according to the new guidelines.

Chronic Pain Is More Likely for Women Who Undergo Armpit Lymph Node Surgery for Breast Cancer

Chronic Pain Is More Likely for Women Who Undergo Armpit Lymph Node Surgery for Breast Cancer

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Risk factors for chronic pain after breast cancer surgery include axillary lymph node dissection, younger age, and radiation therapy. Only axillary lymph node dissection is a high-yield target for a modifiable risk factor to prevent the persistent pain after breast cancer surgery.

Improving Tools for Managing Pain and Monitoring Sedation Among Patients With Cancer

Improving Tools for Managing Pain and Monitoring Sedation Among Patients With Cancer

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Managing pain with opioids and keeping a close eye on adverse effects is an important part of cancer care. But there is room for improvement in pain management tools, and nurses play a key role in their evolution.

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

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Quality of life for patients with oral cancer can be dismal due to cancer-related pain. An NIDCR grant is supporting the investigation of a nonviral gene delivery method for treating oral cancer pain safely and effectively.

Cancer-related Neuropathy May Respond to Gene Therapy

Cancer-related Neuropathy May Respond to Gene Therapy

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Recent research using rats indicates that gene therapy might treat the neuropathic pain that affects 90% of patients with cancer.

VATS Associated With Less Post-op Pain, Better QoL for Stage 1 NSCLC

VATS Associated With Less Post-op Pain, Better QoL for Stage 1 NSCLC

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Video-assisted thoracoscopic surgery (VATS) is associated with less postoperative pain and better quality of life than anterolateral thoracotomy for the first year of surgery in patients with stage I NSCLC.

Study Suggests Clinicians Can Use Opioid of Choice for Breakthrough Cancer Pain

Study Suggests Clinicians Can Use Opioid of Choice for Breakthrough Cancer Pain

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All opioids are currently recommended for breakthrough cancer pain and clinicians may use the opioid of their choice.

Nursing Considerations Regarding Fentanyl Sublingual Spray Titration

Nursing Considerations Regarding Fentanyl Sublingual Spray Titration

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Treatment of breakthrough cancer pain is an important component of care for patients, and nurses should consider various factors when titrating the dose of fentanyl sublingual spray to an effective dose.

Neurofeedback Training Enables Cancer Survivors to Control Chemotherapy-Induced Peripheral Neuropathy

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Chronic pain was decreased and quality of life was increased through neurofeedback.

Optimal management of taxane acute pain syndrome not clear

Optimal management of taxane acute pain syndrome not clear

Despite its prevalence in patients receiving taxane-based chemotherapies, taxane acute pain syndrome (TAPS) remains poorly researched.

Alcohol consumption linked with less disability in chronic pain

Alcohol consumption linked with less disability in chronic pain

Moderate to heavy drinking might cut the likelihood of disability for people with chronic widespread pain.

Combined use of painkillers, antidepressants may increase bleeding risk

Combined use of painkillers, antidepressants may increase bleeding risk

Researchers have found that combined use of antidepressants and NSAID painkillers is associated with an increased risk of bleeding.

'Neuroinvasion' May Impact Cancer Pain, Progression

'Neuroinvasion' May Impact Cancer Pain, Progression

Reciprocal relationship between cancer and neurons at play in tumor proliferation and pain sensitization.

Anesthetic technique could spare some women from chronic pain after breast cancer surgery

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A regional anesthetic technique in combination with standard care could potentially spare a third of women undergoing a mastectomy chronic post-operative pain, according to study data.

First of three phase 3 cancer pain trials shows disappointing results

First of three phase 3 cancer pain trials shows disappointing results

Patients with advanced cancer often do not attain adequate pain relief from optimized chronic opioid therapy.

Pain intensity at presentation is a survival predictor in head and neck cancer

Pain intensity at presentation is a survival predictor in head and neck cancer

Researchers assessed the extent to which pain severity influenced prognosis in patients with newly diagnosed head and neck cancer.

Opioid-related deaths are almost 25% lower in states with medical marijuana laws

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Rates of death resulting from opioid analgesic overdoses are lower in states that allow medical use of marijuana compared with states without such laws.

Acupuncture reduces comorbid symptoms of cancer pain

Acupuncture reduces comorbid symptoms of cancer pain

Electroacupuncture may reduce comorbid symptoms of pain in women with breast cancer who have aromatase inhibitor-related arthralgia, according to research.

Pain and itch may indicate skin cancer

Pain and itch may indicate skin cancer

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Asking patients if a suspicious skin lesion is painful or itchy may help doctors decide whether the spot is likely to be cancerous, according to a new study.

Added corticosteroid not effective for cancer pain

Added corticosteroid not effective for cancer pain

In advanced cancer patients receiving opioids, methylprednisolone does not add to analgesic effect.

How modern medicine can help patients achieve a "good" death

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Overall quality of death of cancer patients who die in an urban Canadian setting with ready access to palliative care was found to be good to excellent in a majority of cases, helping to dispel the myth that suffering at the end of life is inevitable.

Depression and anxiety predict postsurgical pain in women with gynecologic cancer

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Depression and anxiety, not just inflammation, predict pain intensity and interference with daily life among women recovering from gynecologic cancer surgery.

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