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Oxybutynin Chloride Syrup
Overactive bladder/enuresis
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Drug Name:

Oxybutynin Chloride Syrup Rx

Generic Name and Formulations:
Oxybutynin chloride 5mg/5mL.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Oxybutynin Chloride Syrup:

Symptoms of bladder instability associated with voiding in patients with uninhibited neurogenic or reflex neurogenic bladder (eg, urinary urgency, frequency, leakage, urge incontinence, dysuria).

Adult:

5mg 2–3 times a day; max 20mg/day.

Children:

<5yrs: not recommended. ≥5yrs: 5mg twice daily; max 15mg/day.

Contraindications:

Uncontrolled glaucoma. GI obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Severe colitis. Myasthenia gravis. Megacolon. Toxic megacolon in ulcerative colitis. Obstructive uropathies. Unstable cardiovascular status in acute hemorrhage.

Warnings/Precautions:

Activities requiring mental alertness. Diarrhea. Hepatic or renal disease. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hiatal hernia. GI or GU obstruction. Ulcerative colitis. Exposure to extreme heat. Elderly. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Potentiates drowsiness with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics. May be potentiated by CYP3A4 inhibitors. Decreases GI motility, possibly affecting absorption of other drugs.

See Also:

Oxybutynin Chloride Tablets

Pharmacological Class:

Antispasmodic/anticholinergic.

Adverse Reactions:

Dry mouth, constipation, somnolence, headache, diarrhea, nausea, tachycardia, blurred vision, dry eyes, other anticholinergic effects.

Note:

Formerly known under the brand name Ditropan.

How Supplied:

Contact supplier.

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