Ovarian Cancer section

Ovarian Cancer News & Features

Primary Cytoreductive Surgery for HGSC Offers Better Survival Than Neoadjuvant Chemotherapy

Primary Cytoreductive Surgery for HGSC Offers Better Survival Than Neoadjuvant Chemotherapy

Researchers conducted a retrospective cohort analysis to examine patterns of clinical practice in the management of women with advanced HGSC.

Rucaparib Granted FDA Approval for Some Recurring Abdominal Cancers

Rucaparib Granted FDA Approval for Some Recurring Abdominal Cancers

The US FDA granted approval based on results from ARIEL3, a randomized clinical trial conducted with 561 eligible cancer patients.

Fathers Can Pass Inherited Ovarian Cancer Risk to Daughters

Fathers Can Pass Inherited Ovarian Cancer Risk to Daughters

Researchers hypothesize that ovarian cancer may be X-linked and associated genes may be passed from the paternal grandmother via the father's inherited genetic material.

USPSTF Rates Ovarian Cancer Screening a D for Asymptomatic, Low-Risk Women

USPSTF Rates Ovarian Cancer Screening a D for Asymptomatic, Low-Risk Women

An USPSTF updated recommendation statement for ovarian cancer screening recommends against screening for women who are asymptomatic and do not have high-risk hereditary cancer syndrome.

Investigators Examine Link Between Epithelial Ovarian Cancer Risk, Antidepressant Treatment

Investigators Examine Link Between Epithelial Ovarian Cancer Risk, Antidepressant Treatment

Researchers conducted a meta-analysis to examined possible links between antidepressant use and epithelial ovarian cancer, and links between duration and intensity of antidepressant use and risk for epithelial ovarian cancer.

Ovarian, Endometrial Cancer Risk Lower With Long-Term Oral Contraceptive Use

Ovarian, Endometrial Cancer Risk Lower With Long-Term Oral Contraceptive Use

Researchers sought to determine if a correlation was present between extended oral contraceptive use and a decreased risk of certain cancers.

Prevention, Management of Hand-Foot Syndrome With Cooling Therapy

Prevention, Management of Hand-Foot Syndrome With Cooling Therapy

Researchers explored the effectiveness of wearing frozen gloves and socks before and after treatment with PLD to prevent or manage hand-foot syndrome in patients with ovarian cancer.

Hyperthermic intraperitoneal chemotherapy with surgery increases survival for epithelial ovarian cancer patients

1. Patients with stage 3 epithelial ovarian cancer treated with hyperthermic intraperitoneal chemotherapy (HIPEC) in addition to cytoreductive surgery and neoadjuvant chemotherapy experienced increased overall and recurrence-free survival compared to those treated with surgery and chemotherapy alone. 2. No difference in grade 3 or 4 adverse side effects were observed between HIPEC and non-HIPEC treated []

Normal tissue BRCA1 methylation associated with risk for high-grade ovarian cancer

1. BRCA1 promoter methylation in normal white blood cells (WBCs) was linked to risk for high-grade serous ovarian cancer (HGSOC). 2. BRCA1 methylation was detected in women of all ages, including newborns, suggesting that BRCA1 methylation happens at an embryonic stage. Evidence Rating Level: 3 (Average)     Study Rundown: Females with BRCA1 mutations in their germline []

Pazopanib Plus Paclitaxel Does Not Improve Outcomes in Recurrent Ovarian Cancer

Pazopanib Plus Paclitaxel Does Not Improve Outcomes in Recurrent Ovarian Cancer

Results of a double-blind phase 2 study determined if adding oral pazopanib to intravenous paclitaxel improved outcomes for women with recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma.

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