Osteosarcoma

Defects in DNA Imprinting Affect Development and Progression of Childhood Osteosarcoma

Defects in DNA Imprinting Affect Development and Progression of Childhood Osteosarcoma

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Osteosarcoma in children may be impacted by a defect in DNA imprinting that also occurs in their biological parents. These imprinting defects may be predictive of survival outcomes.

Canine osteosarcoma samples identify drivers of metastasis in pediatric bone cancer

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Researchers presenting at the American Association for Cancer Research Annual Meeting 2013 used easily available canine osteosarcoma samples to discover a novel protein that governs metastasis and chemoresistance in pediatric osteosarcoma.

Delayed methotrexate clearance

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What are some common reasons for delayed methotrexate clearance after a 24-hour infusion?

Protein may predict chemotherapy response in osteosarcoma

The expression of the P16 protein, which inhibits cell growth, may be useful for predicting how osteosarcoma will respond to chemotherapy.

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