Oral Cancer

Broccoli Sprout Extracts May Prevent Recurrence of Some Oral Cancers

Broccoli Sprout Extracts May Prevent Recurrence of Some Oral Cancers

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Beverages derived from broccoli sprout extracts were found to have preclinical chemopreventive activity against oral cancer induced by carcinogens.

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

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Quality of life for patients with oral cancer can be dismal due to cancer-related pain. An NIDCR grant is supporting the investigation of a nonviral gene delivery method for treating oral cancer pain safely and effectively.

Prevalence of Oropharyngeal Cancer Survivors on the Rise

Prevalence of Oropharyngeal Cancer Survivors on the Rise

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The prevalence of survivors of oropharyngeal cancer is rising in the United States.

Smokeless Tobacco Users Have Greater Nicotine and Toxin Exposure

Smokeless Tobacco Users Have Greater Nicotine and Toxin Exposure

Exclusive smokeless tobacco users demonstrated higher levels of nicotine and carcinogenic tobacco-specific nitrosamines, compared with exclusive cigarette smokers.

Precision Medicine Trial in Cancer Prevention Identifies Chemoprevention Strategy

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A team of scientists has reported that the genetic biomarker LOH is able to predict which patients with premalignant mouth lesions are at highest risk of developing oral cancer. The findings present a new tool that could be used to identify patients most likely to benefit from chemoprevention.

Neutrophil and cancer cell 'crosstalk' underlies oral cancer metastases

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New research reaffirms the association between inflammatory response and the spread of oral cancer.

Elective Neck Dissection Recommended Standard of Care for Early Oral Cancer

Elective Neck Dissection Recommended Standard of Care for Early Oral Cancer

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Elective neck dissection in clinically node-negative early oral squamous cell carcinoma should be considered the standard of care.

Oral cancers in different locations in smokers vs nonsmokers

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The relatively high incidence of mouth squamous cell cancer in nonsmokers without obvious causes has been noted in studies, with nonsmokers having a higher proportion of cancers occur on the edge of the tongue.

Way to diagnose aggressiveness of oral cancer found

Way to diagnose aggressiveness of oral cancer found

Studying mouth cancer in mice, researchers have found a way to predict the aggressiveness of similar tumors in people, an early step toward a diagnostic test that could guide treatment.

Researchers at NYU and UCSF Develop a Framework for Monitoring Oral Cancer

Researchers at NYU and UCSF Develop a Framework for Monitoring Oral Cancer

Researchers at New York University College of Dentistry and at University of California San Francisco are investigating a potential association between oral cancers and chronic microbial diseases of the oral cavity.

Number of cancer stem cells may not predict outcome in HPV-related oral cancers

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The quality of cancer stem cells, rather than their quantity, may be the factor that leads to better survival in certain patients with oral cancer.

HPV can improve survival for infected African Americans with throat cancer

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The study shows that African Americans with oral and throat cancers who are HPV positive have better outcomes than those without HPV; however, HPV-negative African Americans fared worse than whites with oropharyngeal cancer regardless of HPV status.

USPSTF: Evidence Is Lacking for Oral Cancer Screenings

USPSTF: Evidence Is Lacking for Oral Cancer Screenings

Task force says more work is needed to see if tests can accurately detect oral cancer and improve outcomes.

Gene signature validated for oral cancer metastases

Gene signature validated for oral cancer metastases

Diagnostic signature has negative predictive value of 89 percent for early-stage disease.

Rapamycin may resolve mucositis

Drugs that inhibit mammalian target of rapamycin (mTOR) stopped radiation-induced damage in mice by protecting cells crucial to tissue repair.

Model Accurately Predicts Risk of Oral Cancer Progression

Model Accurately Predicts Risk of Oral Cancer Progression

Model incorporates loss of heterozygosity data.

Gum disease may affect HPV status of head-and-neck tumors

A history of periodontitis may be associated with an increased risk of HPV-positive tumors in persons with head and neck squamous cell carcinoma.

HPV-related oral cancer responds well to robotic surgery

Robotic surgery done through the mouth is effective for squamous cell carcinoma of the throat, particularly in patients with human papillomavirus.

Membrane temperature offers clue to oral mucositis risk in head and neck cancer

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Thermal imaging can detect early changes in the temperature of mucosal surfaces that may signal mucositis in persons with head and neck cancer who are receiving chemoradiotherapy.

ACS annual report says cancer mortality is decreasing

Cancer incidence rates in men declined by 0.6% per year and remained stable in women and cancer mortality fell by 1.8% per year for men and by 1.6% per year for women between 2004 and 2008.

Cancer risk doubles for organ-transplant recipients

Compared with the general population, recipients of a kidney, liver, heart, or lung transplant have twice as great a risk for diverse infection-related and unrelated cancers.

MRI gives SWIFT preoperative indication of jawbone disease in oral cancer

The often difficult task of detecting whether advanced squamous cell carcinoma in the oral cavity has invaded the mandible may be made easier with an MRI technique known as SWIFT.

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