Opioids

Educational Program Improves Opioid Use Safety, Storage, and Disposal

Educational Program Improves Opioid Use Safety, Storage, and Disposal

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This study assessed whether the implementation of a patient educational program would improve patterns in the use, storage, and disposal of opioids among cancer outpatients.

Economic Burden of U.S. Opioid Epidemic is 78.5 Billion Dollars Annually

Economic Burden of U.S. Opioid Epidemic is 78.5 Billion Dollars Annually

Patient abuse of opioids costs the U.S. economy $78.5 billion a year, including the costs of health care, lost productivity, and treatment programs.

Some Older Adults Use High-risk Methods to Obtain Opioids

Some Older Adults Use High-risk Methods to Obtain Opioids

Almost 15 percent of older adults surveyed used high-risk methods for obtaining prescription opioids, according to a recent study.

Use, Outcomes of Urine Drug Tests Among Patients With Advanced Cancer

Use, Outcomes of Urine Drug Tests Among Patients With Advanced Cancer

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Despite the infrequency of urine drug test ordering, greater than half of all urine drug tests results were abnormal among outpatients with advanced cancer.

Methadone May Be Superior to Fentanyl for Neuropathic Pain

Methadone May Be Superior to Fentanyl for Neuropathic Pain

Methadone appears to be superior to fentanyl for the treatment of neuropathic pain in patients with head and neck cancer.

Improving Tools for Managing Pain and Monitoring Sedation Among Patients With Cancer

Improving Tools for Managing Pain and Monitoring Sedation Among Patients With Cancer

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Managing pain with opioids and keeping a close eye on adverse effects is an important part of cancer care. But there is room for improvement in pain management tools, and nurses play a key role in their evolution.

U.S. Medical Schools to Expand Training on Opioid Abuse

U.S. Medical Schools to Expand Training on Opioid Abuse

Health experts note that opioids are prescribed too often, possibly because of poor training, and U.S. medical schools are expanding training to address the issue.

Long-Acting Opioids May Increase All-Cause Mortality Risk

Long-Acting Opioids May Increase All-Cause Mortality Risk

Much of the risk related to long-acting opioids is tied to cardiovascular complications, not overdoses.

ASCO Statement Seeks to Balance Prescription Opioids for Patients With Cancer and Misuse and Abuse Prevention

ASCO Statement Seeks to Balance Prescription Opioids for Patients With Cancer and Misuse and Abuse Prevention

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ASCO addresses the complex issues surrounding prescription opioids in a new policy statement. ASCO supports the efforts of multiple federal offices and agencies to prevent and respond to prescription drug abuse, and is also working to protect access to appropriate medical opioid therapy for patients with cancer.

Promising medication counteracts opioid-caused constipation

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A newly developed opioid antagonist may offer relief from opioid-caused constipation.

Added corticosteroid not effective for cancer pain

Added corticosteroid not effective for cancer pain

In advanced cancer patients receiving opioids, methylprednisolone does not add to analgesic effect.

How to manage myoclonus in patients on high-dose opioids

How to manage myoclonus in patients on high-dose opioids

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How should myoclonus be managed in patients taking high-dose opioids?

FDA urges opioid prescribers to participate in CME training

FDA urges opioid prescribers to participate in CME training

Prescribers of extended-release/long-acting opioid analgesics are encouraged to participate in continuing medical education provided by manufacturers of these analgesics.

FDA: Draft guidance issued on abuse-deterrent opioids

FDA: Draft guidance issued on abuse-deterrent opioids

To assist industry in developing new formulations of opioid drugs with abuse-deterrent properties.

~40 percent of cancer patients receive opioids at end of life

~40 percent of cancer patients receive opioids at end of life

In the U.K., patients older than 60 years less likely to receive prescription versus those younger than 50 years.

ONS Connections: Opioid-induced constipation inadequately addressed

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Opioid-induced constipation is not adequately addressed by nurse practitioners and physicians, according to research presented at the Oncology Nursing Society (ONS) Connections: Advancing Care Through Science conference.

ONS Connections: Opioid titration by oncology nurses leads to more titrations

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Patients who had their opioids managed by clinic nurses who used an opioid titration protocol had more opioid titrations than those who had their opioids managed by standard care, which was their oncologist.

Rapamycin may resolve mucositis

Drugs that inhibit mammalian target of rapamycin (mTOR) stopped radiation-induced damage in mice by protecting cells crucial to tissue repair.

Adding Ketamine to Opioids Doesn't Reduce Cancer Pain

Adding Ketamine to Opioids Doesn't Reduce Cancer Pain

Subcutaneous ketamine as adjunct to opioids has no clinical benefit but does increase toxicity.

Opioids may spur tumor growth

Although opioid-based painkillers are a standard treatment for relieving cancer pain, they may actually contribute to disease progression.

Drug Relieves Opioid-Induced Constipation in Critically Ill

Methylnaltrexone improves bowel function compared with conventional rescue laxatives.

An exit strategy for opioid therapy

An exit strategy for opioid therapy

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What exit strategy do you recommend for discontinuing opioid therapy?

Intracerebroventricular Opioid Infusion Feasible at Home

Intracerebroventricular Opioid Infusion Feasible at Home

Intracerebroventricular (ICV) infusion of opioids is effective for treatment of refractory pain in terminal patients with low incidence of adverse events.

Oncologists need to sharpen their pain-management skills

The results of a recent survey suggest that pain-related knowledge and practice may not be up to par within the oncology community.

New licensing deal for palliative constipation drug

An exclusive worldwide agreement gives Salix Pharmaceuticals licensing rights to Relistor (methylnaltrexone bromide), a treatment for opioid-induced constipation.

Introduce palliative care for pain at cancer diagnosis

Palliative care interventions should be introduced at diagnosis as a part of disease management rather than not until the end of life, suggests a review of cancer pain management.

Morphine sulfate label revised to avoid dosing errors

Roxane Laboratories has made labeling and product-packaging changes to its morphine sulfate oral solution 100 mg per 5 mL (20 mg/mL) due to accidental overdoses that resulted in adverse events and deaths.

Abstral approved for breakthrough cancer pain

A tablet delivering transmucosal fentanyl, Abstral is indicated for the management of breakthrough pain in adult cancer patients who are already using opioids around the clock.

Use evidence-based practice to make your argument

Use evidence-based practice to make your argument

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The goal was to make the case for better pain management without undermining the care team.

Opioid use at home is safe for patients who need pain relief

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Increased doses of opioids during end-of-life care at home is safe to relieve pain and suffering, according to a study published in the Journal of Palliative Medicine (2010 Sep;13(9):1079-83).

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