Oncology

Cancer Now Leading Cause of Death in Many European Nations

Cancer Now Leading Cause of Death in Many European Nations

Gains against cardiovascular disease, especially in Western Europe, is likely a cause for the shift.

Helping Families Cope With Cancer-related Anorexia and Cachexia

Helping Families Cope With Cancer-related Anorexia and Cachexia

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Loss of appetite and not eating are difficult aspects of cancer for patients' loved ones to understand. Continued and diligent nurse education can help both patients and families cope with this disturbing effect.

Coloring as a Relaxation Tool

Coloring as a Relaxation Tool

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The simple childhood pleasure of a coloring book and crayons—or colored pencils, as in this case—provide the foundation of a unique support group for patients with cancer and their families.

Cancer Evolution Analyzed With a Clinically Relevant Perspective

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Current sequencing technology has enabled an analysis of cancer evolution that directs research attention away from the search for genes that enable metastasis and toward genes that are mutated early during tumorigenesis.

ASTRO Develops a Template to Facilitate Radiotherapy-Specific Cancer Survivorship Care Plans

ASTRO Develops a Template to Facilitate Radiotherapy-Specific Cancer Survivorship Care Plans

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As the American College of Surgeons' Commision on Cancer milestones approach, ASTRO publishes a template to ensure consistent, comprehensive survivorship care plans can be developed for cancer survivors whose treatment involved radiotherapy.

Experts' Viewpoint Offers a Salve for Skyrocketing Cancer Drug Prices

Experts' Viewpoint Offers a Salve for Skyrocketing Cancer Drug Prices

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Oncology drug costs continue to rise, and the financial distress patients experience has led many to call for efforts to reduce oncology drug prices. Viable policy interventions will not be free and will involve tradeoffs, according to a team of experts.

Nanotechnology May Enable Detection of Biomarkers, Facilitate Cancer Diagnosis

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A new technology detects disease biomarkers in the form of nucleic acids, which are the molecules that comprise DNA and RNA. The test zeroes in on microRNA, which can signal a wide range of diseases, including cancer.

Potential Drug Targets Are Identified With Finding That Genes in the Ly6 Gene Family Drive Tumorigenesis and Poor Prognosis

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Lower patient survival and worse clinical outcomes across a variety of cancer types were correlated with increased expression of 4 genes in the Ly6 gene family. These findings came from an analysis of 130 gene expression studies from 10 solid cancers.

Interferon Gamma Promotes Anticancer Activity in Macrophages, Enhancing the Immune Response

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New research aims to flip wound-repair (M2 type) macrophages, which promote the growth of cancer, into wound-sterilization (M1 type) macrophages, which may aid the immune system in clearing cancer.

Liquid Biopsy Provides A More Comprehensive View of Genetic Changes Occurring in Cancer Tumors

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Analyzing tumor DNA fragments in the bloodstream, known as circulating tumor DNA (ctDNA), may offer a more complete view of a patient's cancer from a molecular perspective.

Interactions of Cancer-causing Gene May Lead to Therapeutic Target

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An exploration of the interaction between the protein produced by the common cancer-causing KRAS gene and the AGO2 protein may lead to the possibility of interrupting the KRAS-AGO2 interaction as a possible therapy.

Full Disclosure of Data Sharing in Human Research Encourages Patient Participation

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Participation in human research may improve with full disclosure and increased transparency of the risks of participating in publicly shared, big-data research projects.

Meditation Serves as a Coping Tool for Both Patients and Clinicians

Meditation Serves as a Coping Tool for Both Patients and Clinicians

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After experiencing the benefits of meditation to help himself cope with the stress of caring for patients with cancer, this oncologist leads classes teaching those patients to use the tool to better cope with their disease and its effects.

Nanoparticle System Uses Light Waves to Target Release Site of Drug

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Nanoparticles that release a drug only when exposed to near-infrared (NIR) light are a promising drug-delivery agent developed by Canadian researchers.

Development of Microtubulin Inhibitor Is a Potential Lead to Novel Biologic Therapy

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Gatastatin, an inhibitor specific for γ-tubulin, known to be overexpressed in some cancer cells, has been identified and holds potential for the development of anticancer agents.

Understanding Drug Naming Nomenclature

Understanding Drug Naming Nomenclature

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Why do the antibody drugs have such long names?

Optical Probes That Illuminate Solid Tumors in Surgery Move One Step Closer to Reality

Optical Probes That Illuminate Solid Tumors in Surgery Move One Step Closer to Reality

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Optical probes that make cancer cells glow and improve surgical tumor removal are in phase I and II clinical trials in humans. The probes could be commonplace in the next 5 to 10 years, hypothesize the researchers.

Differences in Cancer Rates Seen Among Asian American and Native Hawaiian/Pacific Islander Populations

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Significant differences in cancer rates were found between Asian Americans and Native Hawaiians/Pacific Islanders (AANHPIs), according to a special report within Cancer Facts & Figures 2016.

Initiation of HPV Vaccination Highest Among High-poverty and Majority Hispanic Communities

Initiation of HPV Vaccination Highest Among High-poverty and Majority Hispanic Communities

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Teen girls living in high-poverty and in majority Hispanic communities had the highest rates of having received at least 1 dose of the HPV vaccine compared with those in low-poverty communities and in communities of other racial or ethnic compositions.

Footprint From Cell-free DNA May Indicate Origin of Cancer in Liquid Biopsies

Footprint From Cell-free DNA May Indicate Origin of Cancer in Liquid Biopsies

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A new study suggests that cell-free DNA, tiny fragments of cells in the bloodstream that occur after cells die, may indicate the tissue-of-origin of a cancer, which can be unknown in some cases of metastatic disease.

Initiating Palliative Care in the ED Improves Quality of Life

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Initiating a palliative care consultation in the ED improved quality of life and survival was not shortened in patients with advanced cancer.

Bone Marrow vs PBSCs: Preference of Stem Cell Source for Bone Marrow Failure Varies Worldwide

Bone Marrow vs PBSCs: Preference of Stem Cell Source for Bone Marrow Failure Varies Worldwide

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Sources of stem cells used to treat bone marrow failure vary around the world, with bone marrow harvest more commonly used in areas with more resources. PBSCs are more commonly used in regions with limited resources.

Leading World Cancer Researchers Converge to Create a Report on the Future of Cancer Research

Leading World Cancer Researchers Converge to Create a Report on the Future of Cancer Research

Molecular and cellular events that drive premalignant progression are on the verge of being comprehensively characterized in a report that lays out an agenda for the immediate future of cancer prevention research.

Common Painkiller Has Anticancer Effects

Common Painkiller Has Anticancer Effects

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Diclofenac, a commonly used NSAID, has significant anticancer properties. Preclinical and clinical data indicating its distinct anticancer effects were summarized by the Repurposing Drugs in Oncology project.

Expert Consensus Statement Guides Management of Cardiovascular Treatments for Patients With Cancer

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The Society for Cardiovascular Angiography and Interventions released an expert consensus statement providing guidance for managing the treatment of patients facing concomitant cardiovascular disease and cancer.

Early Trial Results Show Novel Injectable Enables Complete Visualization for Resection of Tumors

Early Trial Results Show Novel Injectable Enables Complete Visualization for Resection of Tumors

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A new injectable agent causes cancer cells in a tumor to fluoresce, potentially enabling surgeons to locate and remove all of a cancerous tumor on the first attempt.

Latest ACS Report Shows Cancer Death Rate Continues to Decline

Latest ACS Report Shows Cancer Death Rate Continues to Decline

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The cancer death rate has dropped by 23% since its peak in 1991, averting more than 1.7 million cancer deaths through 2012, with advances in cancer prevention, early detection, and treatment a part of this rate decline.

Novel Paste Prevents Adverse Skin Effects from Radiotherapy for Cancer

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An antiscarring paste halted the fibrosis caused by the radiation used in cancer therapy when applied to the skin of mice, according to early findings of a recent study.

Certain Characteristics of Clinical Trials May Predict Poor Accrual of Participants

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Researchers identified characteristics that may lead to low patient accrual for a clinical trial.

Newly Identified Protein May Provide a Target for MYC Oncogene Activity in Several Cancers

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Researchers identified a protein that is essential for MYC to cause cancer in mouse models, and they believe, could be a target for anticancer therapy.

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