Generic Name and Formulations:
Thiothixene 1mg, 2mg, 5mg, 10mg; caps.
Indications for Thiothixene:
Individualize. Mild: initially 2mg three times daily, may subsequently increase to 15mg/day. Severe: initially 5mg twice daily. Usual optimal dose: 20–30mg daily; if needed, may increase to max 60mg/day.
Circulatory collapse. Coma. CNS depression. Blood dyscrasias.
Increased mortality in elderly patients with dementia-related psychosis.
Elderly with dementia-related psychosis (not approved use): increased risk of death. History of convulsive disorders or alcohol withdrawal. Exposure to extreme heat. Cardiovascular disease. Pre-existing low WBC or history of drug induced leukopenia/neutropenia; monitor CBCs during 1st few months of treatment. If significant neutropenia occurs; monitor for fever and signs of infections; discontinue if ANC<1000/mm3. Hepatic impairment. Neonates: risk of extrapyramidal and/or withdrawal symptoms post delivery (due to exposure during 3rd-trimester pregnancy). Pregnancy.
Additive effects with hypotensive agents, CNS depressants and alcohol. Potentiates barbiturates. Antagonized by carbamazepine. Caution with concomitant atropine or related drugs.
Tardive dyskinesia, hypotension, drowsiness, insomnia, jaundice, blood dyscrasias, may mask emetic signs of overdosage or disease, lowered seizure threshold, rash, photosensitivity, hyperprolactinemia, anticholinergic effects, pigmentary retinopathy, lenticular pigmentation, extrapyramidal reactions, neuroleptic malignant syndrome (monitor).
Sign Up for Free e-newsletters
- Triplet Regimen Found Most Effective for Relapsed/Refractory Multiple Myeloma
- Integrating Preoperative Oral Care Into Cancer Treatment Plans
- Current Status and Dilemma of Second-line Treatment in Advanced Pancreatic Cancer: Is There a Silver Lining?
- American Association for Cancer Research Releases Its 2018 Annual Report
- Pulmonary Toxicity Increased in Pediatric Hodgkin Lymphoma Treated With Brentuximab Vedotin
- Benefit of Chemotherapy for Breast Cancer Observed With Midrange Gene Assay Score
- Antioxidant Interaction With Cancer Therapy
- Young Survivors of Breast Cancer Report Sexual Quality of Life Declines After Treatment
- Myeloablative Conditioning Effective in AML Secondary to MDS/MPN Prior to Allogeneic HCT
- Insurance Status Influences Overall Survival in Follicular Lymphoma
- Endocrine Society Released Guidelines for Managing Endocrine Disorders in Childhood Cancer Survivors
- Skin Cancer Screening: Are They Effective?
- Metronidazole, Vancomycin Recommended for C Difficile in Pediatric Oncology, HSCT
- CDC: HPV Vaccination Rates on the Rise Among Adolescents
- High-Dose vs Standard-Dose Flu Vaccine in Elderly Receiving Chemotherapy
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|