ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

NAMENDA XR
Alzheimer's dementia
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

NAMENDA XR Rx

Generic Name and Formulations:
Memantine HCl 7mg, 14mg, 21mg, 28mg; ext-rel caps.

Company:
Allergan

Therapeutic Use:

Indications for NAMENDA XR:

Moderate-to-severe dementia of the Alzheimer's type.

Adult:

Do not divide doses. Swallow whole or may open caps and sprinkle on applesauce, then consume entire contents. Initially 7mg once daily; titrate at intervals of at least 1 week in increments of 7mg to target dose of 28mg once daily. Max 28mg once daily. Severe renal impairment (CrCl 5–29mL/min): titrate to target dose of 14mg/day. Switching from immediate-release tabs: give XR caps the day after last dose of immediate-release tabs; see full labeling.

Children:

Not established.

Warnings/Precautions:

Severe hepatic impairment. Alkalinized urine (eg, renal tubular acidosis, severe UTI) increases memantine serum levels. Seizure disorder. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Caution with other NMDA antagonists (eg, amantadine, ketamine, dextromethorphan). May affect or be affected by renally-excreted drugs (eg, triamterene, HCTZ, metformin, cimetidine, nicotine, ranitidine, quinidine). Plasma levels may be increased by urinary alkalinizers.

See Also:

NAMENDA

NAMENDA ORAL SOLUTION

Pharmacological Class:

NMDA receptor antagonist.

Adverse Reactions:

Headache, dizziness, confusion, diarrhea, constipation, hypertension, pain, somnolence, hallucination, urinary disorders, dyspnea.

Metabolism:

Hepatic (partial).

Elimination:

Renal.

Generic Availability:

Tabs (YES); Oral soln, XR caps (NO)

How Supplied:

Tabs—60; Titration Pak (28 x 5mg + 21 x 10mg)—1; Oral soln—360mL; XR caps 7mg, 21mg—30; 14mg, 28mg—30, 90; XR Titration Pak (7 x 7mg + 7 x 14mg + 7 x 21mg + 7 x 28mg)—1

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs