Myeloproliferative Neoplasms section

Myeloproliferative Neoplasms News & Features

Clinical Benefit of Simtuzumab Inconsistent for Myelofibrosis

Clinical Benefit of Simtuzumab Inconsistent for Myelofibrosis

Simtuzumab is well-tolerated but has inconsistent clinical benefit for patients with myelofibrosis.

Blood Test Predicts Stem Cell Transplant Success in Myelodysplastic Syndrome

Blood Test Predicts Stem Cell Transplant Success in Myelodysplastic Syndrome

Blood test combined with medical status information predicts stem cell transplant success in patients with MDS.

Anxiety, Distress Common Among Patients With BCR-ABL-negative MPNs

Anxiety, Distress Common Among Patients With BCR-ABL-negative MPNs

In this study, researchers measured the psychological manifestations among patients with BCR-ABL-negative MPNs to determine the effects of anxiety, distress, and depression on symptom burden in this patient population.

Azathioprine Associated With Increased Risk of Myeloid Neoplasms

Azathioprine Associated With Increased Risk of Myeloid Neoplasms

Azathioprine for the treatment of autoimmune disorders is significantly associated with an increased risk of acute myeloid leukemia and myelodysplastic syndromes.

Continued Hydroxyurea vs Switching to Ruxolitinib for Polycythemia Vera

Continued Hydroxyurea vs Switching to Ruxolitinib for Polycythemia Vera

Ruxolitinib is proven superior to best available therapy for polycythemia vera with inadequate response or intolerance of hydroxyurea. This study evaluates the impact of continued hydroxyurea vs switching to ruxolitinib on disease-related symptom burden.

Women With Myeloproliferative Neoplasms Appear to Have Successful Pregnancies

Women With Myeloproliferative Neoplasms Appear to Have Successful Pregnancies

Evidence suggests that women with myeloproliferative neoplasms have a higher risk of maternal and fetal complications. In this data analysis, researchers evaluated outcomes for pregnant women with essential thrombocythemia, polycythemia, or myelofibrosis and their infants.

Polycythemia Vera (Fact Sheet)

Polycythemia Vera (Fact Sheet)

This fact examines the possible causes, risk factors, symptoms, and treatments associated with polycythemia vera.

Hydroxyurea May Improve Kidney Function in PV-Associated Nephrotic Syndrome

Hydroxyurea May Improve Kidney Function in PV-Associated Nephrotic Syndrome

The clinical course of a patient with polycythemia vera and proteinuria whose biopsy lead to a diagnosis of focal segmental glomerulosclerosis is described.

Patients With MPNs, Physicians View Treatment Goals Differently

Patients With MPNs, Physicians View Treatment Goals Differently

Patients with myeloproliferative neoplasms, such as polycythemia vera and myelofibrosis, and their physicians frequently view the assessment of disease prognosis, disease burden, and treatment goals differently.

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