Simtuzumab is well-tolerated but has inconsistent clinical benefit for patients with myelofibrosis.
Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a new study.
The researchers have mapped the steps used by cells of melanoma, breast cancer, and the blood cancer myelofibrosis to become resistant to drugs, allowing for better success in blocking these pathways and further enabling therapies.
The compound PRM-151 (PRM) has shown success in reducing progressive bone marrow fibrosis in patients with advanced myelofibrosis.
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