Myelodysplastic Syndrome

Molecular Signature Predicts Transition from Myelodysplastic Syndrome to Acute Myeloid Leukemia

By

Progress from myelodysplastic syndrome to AML is linked to the enzyme glycogen synthase kinase, and a molecular signature is found to predict clinical outcomes of patients with MDS.

Combination therapy effective for patients with higher-risk myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML)

Combination therapy effective for patients with higher-risk myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML)

By

Combined treatment with azacitidine and lenalidomide may be an effective frontline treatment regimen for patients with higher-risk forms of myelodysplastic syndrome and acute myeloid leukemia.

Age alone should not limit access to stem cell transplants for patients with MDS

By

Patients with myelodysplastic syndrome age 66 to 74 years did as well with stem cell transplantation as patients age 60 to 65 years. This research was presented at the 2013 ASH Annual Meeting, in New Orleans.

Anemia in patients with MDS

Anemia in patients with MDS

By

Managing anemia in patients with myelodysplastic syndrome (MDS) is complex. When are erythroid growth factors used as primary treatment?

Withdrawn leukemia drug has good results in UK study

Gemtuzumab ozogamicin, discontinued here in 2010, reduced relapse risk and improved survival in Welsh patients with acute myeloid leukemia.

HIV drug can prevent complications after stem-cell transplant

An HIV drug helped lower the risk of graft-versus-host disease in persons with blood cancer who had stem-cell transplants to rebuild bone marrow.

FDA Update: May/June 2012

Drug Safety Communication on lenalidomide (Revlimid); FDA approval for pazopanib (Votrient)

Specific Mutations in AML Affect Response to Therapy

Specific Mutations in AML Affect Response to Therapy

Also, bone marrow cells in myelodysplastic syndromes, secondary AML are clonal.

Comparable Clinical Activity for Low-, High-Dose Clofarabine

Comparable Clinical Activity for Low-, High-Dose Clofarabine

More adverse effects seen for high dose in patients with higher-risk myelodysplastic syndrome

Myelodysplasia gene mutation can aid diagnosis

The recent discovery of gene mutations in a genomic study of myelodysplastic syndromes could enable diagnosis using only a blood test rather than a bone marrow biopsy.

Family studies reveal leukemia gene

A genetic defect found on the GATA2 gene predisposes people to acute myeloid leukemia (AML) and myelodysplasia, researchers have learned.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs