Multiple Myeloma section

Multiple Myeloma News & Features

Tandem Autologous-Allogenic HCT Offers Long-Term Remission in Multiple Myeloma

Tandem Autologous-Allogenic HCT Offers Long-Term Remission in Multiple Myeloma

A retrospective follow-up study demonstrates that tandem autologous-allogeneic is safe for standard and high-risk multiple myeloma. However, benefits do not extend to patients with ultra-high-risk disease and those with disease progression after autologous HCT.

Triplet Regimen Found Most Effective for Relapsed/Refractory Multiple Myeloma

Triplet Regimen Found Most Effective for Relapsed/Refractory Multiple Myeloma

An updated network meta-analysis found that a triplet regimen consisting of lenalidomide and dexamethasone plus an immunotherapeutic agent had better efficacy in terms of NRR, TTP, PFS, and OS than other regimens.

Clarithromycin Plus Bortezomib May Be Ineffective, Toxic in Multiple Myeloma

Clarithromycin Plus Bortezomib May Be Ineffective, Toxic in Multiple Myeloma

Researchers found that clarithromycin plus bortezomib does not confer any additional efficacy and is a toxic in patients with multiple myeloma.

A Novel Formulation of Melphalan May Not Prevent Complications Post-ASCT in Multiple Myeloma

A Novel Formulation of Melphalan May Not Prevent Complications Post-ASCT in Multiple Myeloma

High-dose melphalan is a frequently before ASCT in MM, but is associated with high rates of adverse events.

PVX-410 Vaccine May Delay Disease Progression of Smoldering Multiple Myeloma

PVX-410 Vaccine May Delay Disease Progression of Smoldering Multiple Myeloma

Reinforcing the immune system with a the PVX-410 vaccine may prevent or slow progression to multiple myeloma.

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