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MONOVISC
Arthritis/rheumatic disorders
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Drug Name:

MONOVISC Rx

Generic Name and Formulations:
Sodium hyaluronate 22mg/mL; viscoelastic soln for intra-articular inj.

Company:
Anika Therapeutics

Therapeutic Use:

Indications for MONOVISC:

Treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy or simple analgesics (eg, acetaminophen).

Adult:

Remove synovial fluid or effusion before inj. Give as a single intra-articular inj. 4mL in one knee only. If bilateral treatment: use one syringe in each knee.

Children:

≤21yrs: not established.

Contraindications:

Gram (+) bacterial protein allergy. Infections or skin diseases in area of inj site/joint. Systemic bleeding disorders.

Warnings/Precautions:

Avoid strenuous or prolonged weight-bearing activities within 48hrs following inj. Pregnancy, nursing mothers: not established.

Interactions:

Avoid use of disinfectants containing quaternary ammonium salts; hyaluronan can precipitate in their presence.

Pharmacological Class:

Hyaluronan.

Adverse Reactions:

Arthralgia, joint swelling, inj site pain.

Generic Availability:

NO

How Supplied:

Single-use syringe (4mL)—1

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