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MONOKET
Angina
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Drug Name:

MONOKET Rx

Generic Name and Formulations:
Isosorbide mononitrate 10mg, 20mg; scored tabs.

Company:
Kremers Urban Pharmaceuticals

Therapeutic Use:

Indications for MONOKET:

Prophylaxis and treatment of angina. Not for acute attacks.

Adult:

20mg upon awakening then 20mg 7 hrs later. Small patients: may start with 5mg per dose for 1 day, then increase to 10mg by 2nd or 3rd day (scheduled as above).

Children:

Not established.

Contraindications:

Concomitant PDE-5 inhibitors (eg, sildenafil, tadalafil, vardenafil), riociguat.

Warnings/Precautions:

Acute MI. CHF. Hypotension. Volume depletion. Hypertrophic cardiomyopathy. Monitor for tolerance. Pregnancy (Cat.B). Nursing mothers.

Interactions:

See Contraindications. Severe hypotension, syncope, or myocardial ischemia with PDE-5 inhibitors; or hypotension with riociguat. Orthostatic hypotension with alcohol, other vasodilators, calcium channel blockers.

Pharmacological Class:

Nitrate.

Adverse Reactions:

Headache, dizziness, orthostatic hypotension, GI upset, upper respiratory infection.

How Supplied:

Tabs—100

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