Monoclonal Gammopathy Of Undetermined Significance (MGUS)

Firefighters in World Trade Center Attacks Have Increased Risk of Multiple Myeloma

Firefighters in World Trade Center Attacks Have Increased Risk of Multiple Myeloma

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A case series demonstrates the prevalence of MGUS, a precursor condition to multiple myeloma, and subsequent development of MM in white firefighters who responded after the 9/11 attacks in New York City.

Shorter overall survival among patients with monoclonal gammopathy of undetermined significance

1. Patients diagnosed with monoclonal gammopathy of undetermined significance (MGUS) and followed for multiple decades showed shorter overall survival rates compared to matched controls. 2. Risk of progression to multiple myeloma or another blood cell disorder was associated with identified adverse risk factors. Evidence Rating: 1 (Excellent) Study Rundown: MGUS is a relatively common condition []

Gene Expression Alters Bone Marrow Environment in MGUS, Leading to Multiple Myeloma

Gene Expression Alters Bone Marrow Environment in MGUS, Leading to Multiple Myeloma

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Researchers discovered that changes in the bone marrow needed for multiple myeloma to grow have already taken hold in patients with MGUS.

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