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MIACALCIN INJECTION
Bone disorders
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Drug Name:

MIACALCIN INJECTION Rx

Generic Name and Formulations:
Calcitonin-salmon 200 IU/mL; soln for SC or IM inj.

Company:
Mylan Inc.

Therapeutic Use:

Indications for MIACALCIN INJECTION:

Paget's disease of bone. Hypercalcemia. Postmenopausal osteoporosis in women >5yrs postmenopausal.

Adult:

Give by IM inj across multiple sites if total dose >2mL. Paget's: 100 IU SC or IM daily. Hypercalcemia: initially 4 IU/kg SC or IM every 12hrs, may increase after 1–2 days to 8 IU/kg every 12hrs, and then after 2 more days to max 8 IU/kg every 6hrs. Postmenopausal osteoporosis: 100 IU SC or IM daily.

Children:

Not established.

Warnings/Precautions:

Correct hypocalcemia and other mineral metabolism disorders before initiating; monitor serum calcium and hypocalcemia symptoms during therapy. Increased risk of malignancies. Consider periodic exams of urine sediment; serum alkaline phosphatase and urinary hydroxyproline in Paget's. Postmenopausal osteoporosis: supplement diet with calcium 1g/day and Vit.D 400 IU/day. Re-evaluate periodically. Pregnancy. Nursing mothers.

Interactions:

May antagonize lithium (consider lithium dose adjustment).

Pharmacological Class:

Hormone.

Adverse Reactions:

Nausea, vomiting, local inflammation, flushing, rash; hypersensitivity reactions, anaphylaxis, hypocalcemia, antibody formation.

How Supplied:

Multi-dose vials (2mL)—1

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