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MENHIBRIX
Vaccines
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Drug Name:

MENHIBRIX Rx

Generic Name and Formulations:
Neisseria meningitidis polysaccharides 5mcg each of Groups C and Y (tetanus toxoid conjugate [5mcg and 6.5mcg]) + Haemophilus b polysaccharides 2.5mcg (tetanus toxoid conjugate 6.25mcg); per 0.5mL; lyophilized pwd for IM inj after reconstitution; contains trometamol, sucrose, residual formaldehyde; latex-, preservative-free.

Company:
GlaxoSmithKline

Therapeutic Use:

Indications for MENHIBRIX:

Immunization against N. meningitidis serogroups C and Y, and H. influenzae type b in children 6 weeks through 18 months of age.

Adult:

Not applicable.

Children:

<6 weeks or 19 months–16 years: not established. Give by IM inj in anterolateral thigh (if <1year old) or in deltoid muscle. 0.5mL given as a 4-dose series at 2, 4, 6, and 12–15 months of age. May give 1st dose as early as 6 weeks and 4th dose as late as 18 months of age.

Contraindications:

Severe allergic reaction to any previous dose of meningococcal-, H. influenza type b-, or tetanus toxoid-containing vaccine.

Warnings/Precautions:

Not a substitute for routine tetanus immunization. Guillain-Barre syndrome within 6 weeks of a previous tetanus toxoid-containing vaccine. Immunosuppressed. Have epinephrine inj (1:1000) available. Pregnancy (Cat. C).

Interactions:

Concomitant vaccines: see full labeling. Immunosuppressive therapies (eg, irradiation, antimetabolites, alkylating agents, cytotoxic drugs, high-dose corticosteroids) may get suboptimal response.

Adverse Reactions:

Local inj site reactions (eg, pain, redness, swelling), irritability, drowsiness, loss of appetite, fever; syncope, apnea in premature infants.

How Supplied:

Single-dose vials—10 (w. diluent)

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