Melanoma Cancer section

Melanoma News & Features

Study Identifies Factors Associated With Outcomes After Dabrafenib + Trametinib

Despite the effectiveness of dabrafenib in combination with trametinib for metastatic BRAF-mutant melanoma, many patients experience disease progression that often leads to death. In this data analysis, researcher sought to identify clinical factors associated with long-term response and survival.

PD-1 Inhibitors Ideal for First-Line Therapy in Treatment-Naïve Advanced Melanoma

PD-1 Inhibitors Ideal for First-Line Therapy in Treatment-Naïve Advanced Melanoma

Atlhough survival for patients with advanced melanoma is similar with both targeted therapies and immunotherapies, a review of the literature reveals why one of them may be a better choice as first-line therapy.

Immune Checkpoint-Related Neurotoxicity May Be More Common During Combination Treatment

Immune Checkpoint-Related Neurotoxicity May Be More Common During Combination Treatment

Neurotoxicity is not uncommon in patients with melanoma treated with immune checkpoint inhibitors. In this study, therefore, researchers sought to examine the incidence of neurotoxicity across anti-CTLA-4 and anti-PD-1 antibodies at a single institution.

More Than Half of Melanomas Are Self-Detected, Especially by Women

More Than Half of Melanomas Are Self-Detected, Especially by Women

More melanomas are self-detected by women; men tend to have more melanomas in less visible locations.

Psychoeducational Intervention Effective for Reducing Fear of Melanoma Recurrence

Psychoeducational Intervention Effective for Reducing Fear of Melanoma Recurrence

A newly developed, evidence-based psychoeducational intervention effectively reduced fear of cancer recurrence and stress in patients at high risk for developing another melanoma.

HRQoL Better Maintained With Pembrolizumab in Ipilimumab-refractory Melanoma

HRQoL Better Maintained With Pembrolizumab in Ipilimumab-refractory Melanoma

Treatment with pembrolizumab better maintained health-related quality of life compared with chemotherapy in patients with advanced melanoma refractory to ipilimumab.

Experimental Drug Shows Promise in Melanoma Treatment

Experimental Drug Shows Promise in Melanoma Treatment

Pevonedistat was effective for inhibiting proliferation of melanoma cell lines in vitro, research indicates.

Supportive Care Needs Assessed in Localized Cutaneous Melanoma

Supportive Care Needs Assessed in Localized Cutaneous Melanoma

Patients with localized melanoma see their supportive care needs peak at their initial cancer diagnosis and if they experience disease recurrence.

Study Supports Use of PD-1 Inhibitors in Acral, Mucosal Melanomas

Response rates with PD-1 inhibitors in patients with acral and mucosal melanomas were similar to previously reported rates in patients with cutaneous melanoma.

Some Gene Variants Increase the Risk for Melanoma in People With Red Hair, Freckling

Some Gene Variants Increase the Risk for Melanoma in People With Red Hair, Freckling

Variants of the MC1R gene, associated with red hair, pale skin, and freckles, increases the number of genetic mutations related to skin cancer and the level of other gene mutations, further increasing the risk for skin cancer.

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