Melanoma Cancer section

Melanoma News & Features

SPF30 Sunscreens Delay Melanoma in Preclinical Model

SPF30 Sunscreens Delay Melanoma in Preclinical Model

Melanoma onset was delayed by applying sun protection factor 30 (SPF30) sunscreen prior to exposure to ultraviolet-B light in a mouse model of the disease.

Study Pools Data to Evaluate Melanoma Outcomes After Pembrolizumab

Among patients with advanced melanoma, the human PD-1-blocking antibody pembrolizumab was associated with an overall objective response rate of 33%, 12-month progression-free survival rate of 35%, and median overall survival of 23 months.

Melanoma Tumor Cells Respond Differently to Therapy in Elderly Patients Than in Younger Patients

Melanoma Tumor Cells Respond Differently to Therapy in Elderly Patients Than in Younger Patients

Therapy for the elderly with melanoma may be affected by findings that aged tumor cells in melanoma behave differently than younger tumor cells.

Sun Exposure Beneficial Despite the Risk of Melanoma

Sun Exposure Beneficial Despite the Risk of Melanoma

Though sunbathers are at an increased risk of developing skin cancer, women who sunbathe are likely to live longer than those who avoid the sun.

Microneedle Patch Delivers Localized Immunotherapy for Melanoma

Microneedles embedded in a patch deliver cancer immunotherapy treatment directly to the site of melanoma, according to preliminary findings in animal studies.

MC1R Variants May Increase Melanoma Risk, Even Without Sun Exposure

MC1R Variants May Increase Melanoma Risk, Even Without Sun Exposure

Variant of gene linked to skin pigmentation may be tied to higher melanoma risk.

Higher Mole Count Doesn't Always Correspond to Higher Melanoma Risk

Higher Mole Count Doesn't Always Correspond to Higher Melanoma Risk

Physicians shouldn't rely on mole count as the only reason to perform skin exams for melanoma.

HIV Drug Could Re-sensitize Therapy-resistant Melanoma

HIV Drug Could Re-sensitize Therapy-resistant Melanoma

The expression of the PAX3 and MITF genes in melanoma can cause early, nonmutational, reversible drug resistance; tissues that express these genes can then later develop mutational, irreversible drug resistance. The HIV drug nelfinavir can prevent this resistance.

Prognosis Poor for Women With Pregnancy-Associated Melanoma

Prognosis Poor for Women With Pregnancy-Associated Melanoma

Among women aged up to 49 years with a pregnancy-associated melanoma, recurrence rates were higher than seen in other groups.

Melanoma Therapy Associated With Cutaneous Events

Melanoma Therapy Associated With Cutaneous Events

Anti-programmed cell death-1 therapy tied to lichenoid reactions, eczema, vitiligo

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