Melanoma Cancer section

Melanoma News & Features

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

Investigators sought to compare the prognostic value of sentinel lymph node status vs Breslow thickness in patients with cutaneous melanoma.

Presence of Iris Pigmented Lesions Indicates Melanoma Risk

Presence of Iris Pigmented Lesions Indicates Melanoma Risk

The likelihood for development of cutaneous melanoma may be greater for individuals with iris pigmented lesions, according to a study.

Age Not a Deterrent to Immunotherapy for Malignant Melanoma

Age Not a Deterrent to Immunotherapy for Malignant Melanoma

Investigators sought to evaluate whether age is associated with risk for immune-related adverse events among patients with metastatic melanoma treated with immunotherapy.

Adjuvant Vemurafenib Does Not Improve Disease-Free Survival in Melanoma

Adjuvant Vemurafenib Does Not Improve Disease-Free Survival in Melanoma

Researchers report on finding of a double-blind phase 3 study on the efficacy of adjuvant vemurafenib in patients with resected stage IIC to IIIB melanoma.

Induced Pluripotent Stem Cell Vaccine May Help Prevent Tumor Growth

Induced Pluripotent Stem Cell Vaccine May Help Prevent Tumor Growth

iPSC vaccine prevented tumor growth in syngeneic murine breast CA, mesothelioma, melanoma models

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

A retrospective study evaluated the relationship of BMI with survival outcomes among patients with metastatic melanoma who received targeted therapy, immunotherapy, or chemotherapy.

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

The FDA granted approval for nivolumab for adjuvant treatment of some patients with melanoma, based on the results of the CHECKMATE-238 study.

Potential for Metastatic Melanoma Cure Seen in High CR Rate With Pembrolizumab

Potential for Metastatic Melanoma Cure Seen in High CR Rate With Pembrolizumab

Baseline tumor size and PD-L1 status were independently associated with the likelihood of a complete response.

Distinct Patterns of Shiny White Streaks Strong Indicator of Melanoma

Distinct Patterns of Shiny White Streaks Strong Indicator of Melanoma

Patients presenting with lesions with shiny white streaks on dermoscopy should undergo biopsy for possible melanoma.

Melatonin Derivatives Exhibit Cytotoxic Activity in Melanoma and Breast Cancer

Melatonin Derivatives Exhibit Cytotoxic Activity in Melanoma and Breast Cancer

Melatonin and its analogues, in addition to their ability to regulate circadian rhythms, may exhibit cytotoxic activity via various cellular mechanisms.

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