Medulloblastoma

Novel Drug Combination Inhibits Growth of MYC-driven Medulloblastoma

By

The growth of medulloblastoma was inhibited by a new drug in research conducted in cell cultures and mice. This study targeted a particularly aggressive form of the disease driven by the oncogene MYC.

Proton Radiotherapy May Be Viable Option for Pediatric Brain Tumor

Proton Radiotherapy May Be Viable Option for Pediatric Brain Tumor

Phase 2 trial data showed acceptable toxicity and similar survival as conventional radiotherapy for childhood medulloblastoma.

Imaging technique allows pediatric brain tumors to be classified noninvasively at diagnosis

By

Researchers have discovered that determining a tumor's medulloblastoma subgroup can be achieved noninvasively, using magnetic resonance spectroscopy (MRS).

Common class of channel blockers may find a role in cancer therapy

By

Ion channel blockers, drugs commonly used to treat cardiac, neurologic, and psychiatric disorders, might prove useful in cancer therapy, according to new research.

Targeted therapy for skin cancer is effective in patients with sonic hedgehog (SHH) subtype of medulloblastoma

By

A targeted therapy already used to treat advanced skin cancer has also been found to be effective when used to treat the most common subtype of adult medulloblastoma.

Repurposing antidepressant may target new medulloblastoma pathway

By

New research suggests that an antidepressant medication, repurposed, could target a novel molecular pathway that causes an aggressive form of medulloblastoma.

Adult cancer drug offers hope against aggressive pediatric brain tumor

By

The quest to improve survival of children with a high-risk brain tumor has led investigators to two drugs already used to treat adults with breast, pancreatic, lung, and other cancers.

Fundamental differences exist between human cancers and genetically engineered mice

By

A specific epigenetic modification may be fundamentally different between primary human medulloblastomas and GEMMs of medulloblastoma, according to a new study.

Deviations from radiation protocols increase the risk of treatment failure and death

By

When measures are implemented to ensure that radiation protocols are followed, deviations decrease and overall survival improves in patients with cancer.

New radiation treatment method merciful for children with brain tumors

By

For children who undergo brain radiation therapy, permanent neurocognitive adverse effects are a significant risk. These risks arise because the radiation often encounters healthy tissue, which reduces the formation of new cells, particularly in the hippocampus.

Adding Radiation Aids Pediatric Nonmetastatic Medulloblastoma

Adding Radiation Aids Pediatric Nonmetastatic Medulloblastoma

Induction chemotherapy plus conformal radiation therapy improves event-free survival.

FoxM1 protein may hold key to treatment of pediatric brain tumor

The regulatory protein FoxM1 is essential for the continued growth of medulloblastoma and is significantly and negatively correlated with survival, making it a useful prognostic marker.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs