Lymphoma News and Features

Relapse of diffuse large B-cell lymphoma not detected by imaging scans

Imaging scans following treatment for diffuse large B-cell lymphoma do little to help detect a relapse, according to a new study. The overwhelming majority of patients with this aggressive lymphoma already have symptoms, an abnormal physical examination or an abnormal blood test at the time of relapse, researchers say.

Adcetris being reviewed for retreatment, extended duration therapy

The FDA has accepted Seattle Genetics' sBLA for filing of Adcetris for retreatment and extended duration beyond 16 cycles of therapy in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma.

Nursing Safety Procedures Essential in Caring for Patients with NHL Receiving Radioimmunotherapy

Nurses play a critical role in promoting safety for patients with indolent forms of non-Hodgkin lymphoma receiving radioimmunotherapy, according to research presented at the ONS 38th Annual Congress.

Alternative type of enteropathy-associated T-cell lymphoma is identified

An international research team has identified a new type of deadly intestinal lymphoma that is particularly common in Asia. The team also developed a new diagnostic test to accurately identify the disease.

Nanodelivery of arsenic fights lymphoma while preserving fertility

Packaging crystalline arsenic particles in a bubble of fat helps deliver the drug into lymphoma cells without damaging the ovaries.

Master protein in aggressive lymphomas can be shut down

Researchers at Weill Cornell Medical College report that it is possible to shut down the master regulatory transcription factor Blc6 in DLBCL while not affecting its vital function in the T cells and macrophages needed to support a healthy immune system.

Radiation effects could be gauged by small molecules in the blood

Molecules in the bloodstream that might accurately gauge the likelihood of radiation illness after exposure to ionizing radiation have been identified. This animal study shows that X-rays or gamma rays alter the levels of certain molecules called microRNA (miRNA) in the blood in a predictable way.

Leukemia after chemotherapy is a growing risk

Persons who have undergone cytotoxic chemotherapy for certain cancers, notably non-Hodgkin lymphoma, may develop acute myeloid leukemia.

High-dose vorinostat is effective in relapsed lymphomas

High doses of vorinostat (suberoylanilide hydroxamic acid) in combination with another round of commonly used second-line drugs produced a 70% response rate in patients with aggressive, relapsed lymphoma, including complete elimination of lymphoma cells in several patients.

Gold nanoparticles kill lymphoma without chemotherapy

Lymphoma can be starved to death by depriving it of what appears to be a favorite food: HDL cholesterol. A new nanoparticle appears to the cancerous lymphoma cell like a preferred meal of natural HDL.

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