Lymph Nodes

Staging by Lymph Node Categories Shown to Better Predict Survival in Patients With Oropharyngeal Cancer

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The current staging system for oropharyngeal cancer does not adequately differentiate HPV-positive from HPV-negative OPC. These researchers suggest regional OPC lymph node (N) categories and nasopharyngeal N categories might be more useful in staging HPV-positive OPC.

Interferon Has Little Benefit for Patients With Small Amounts of Melanoma in the Lymph Nodes

Interferon Has Little Benefit for Patients With Small Amounts of Melanoma in the Lymph Nodes

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No evidence that interferon is necessary or helpful in cases of melanoma with minimal metastasis to the lymph nodes, according to the final results of the Sunbelt Melanoma Trial.

Radiotherapy to the Axilla Can Replace Axillary Lymph Node Dissection in Select Patients

Radiotherapy to the Axilla Can Replace Axillary Lymph Node Dissection in Select Patients

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Recent trial data indicate that axillary lymph node dissection (ALND) can be safely omitted in select patients, according to a research presented at the 2015 San Antonio Breast Cancer Symposium.

Internal Mammary Lymph Nodes Discovered With MRI Likely to Be Benign

Internal Mammary Lymph Nodes Discovered With MRI Likely to Be Benign

Internal mammary lymph nodes (IMLNs) identified at implant-protocol breast magnetic resonance imaging (MRI) are more likely to be benign than malignant.

Adding regional nodal irradiation to whole-breast irradiation reduces breast cancer recurrence

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Radiation to the lymph nodes as well as the standard treatment of whole-breast irradiation after breast-conserving surgery does not confer an overall survival benefit.

Regional node irradiation in breast cancer improves overall survival

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The effect of irradiation of regional nodes in patients with stage I, II, or III breast cancer on overall survival is very limited, according to a study.

Extended-Field IMRT Does Not Increase Risk of Duodenal Toxicity

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Women with cervical or endometrial cancer can safely receive extended-field intensity modulated radiation therapy (EF-IMRT) without increased risk of duodenal toxicity.

Growth of lymph node metastases does depend on new blood vessel development

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The growth of metastases in lymph nodes does not require new blood vessels, but rather utilizes existing blood vessels.

Axillary lymph node evaluation performed frequently in DCIS

Axillary lymph node evaluation performed frequently in DCIS

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Although not usually recommended for women with localized cancer undergoing breast-conserving surgery, axillary lymph node evaluation is performed frequently in women with ductal carcinoma in situ (DCIS) breast cancer.

Ultrasound helps determine which breast cancer patients need lymph nodes removed

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Not all women with lymph node-positive breast cancer treated with chemotherapy before surgery need to have all underarm nodes removed, new research indicates.

Risk stratification model aids lung cancer staging and treatment decisions

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A risk stratification model, based on lymph node characteristics, can confirm a negative classification of lung cancer with a high level of confidence.

Racial disparities in breast cancer care extends to lymph node biopsy

Racial disparities in breast cancer care extends to lymph node biopsy

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A study from the University of Texas MD Anderson Cancer Center reveals a disparity in use of sentinel lymph node biopsy between black and white women.

Racial disparity seen in sentinel lymph node biopsy

Racial disparity seen in sentinel lymph node biopsy

Although sentinel lymph node biopsy (SLNB) use has increased in all patients with breast cancer, black women are consistently less likely than white women to have SLNB, according to a study.

ASBS: Radiotherapy better for node-positive breast cancer

ASBS: Radiotherapy better for node-positive breast cancer

For patients with breast cancer with a positive sentinel node treatment with axillary lymph node dissection is associated with more morbidity than axillary radiotherapy, according to a study.

Rib cage lymph nodes are prognostic for mesothelioma

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For the first time, researchers have shown the predictive power of a group of overlooked lymph nodes that could serve as a better tool to stage and ultimately treat patients with malignant pleural mesothelioma.

Treating chest lymph nodes improves survival in early breast cancer

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Giving radiation therapy to the lymph nodes located behind the breast bone and above the collar bone to patients with early breast cancer improves overall survival without increasing side effects.

MicroRNA-31 might predict lung cancer spread to lymph nodes

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Measuring levels of the molecule microRNA-31 might accurately determine if a patient's lung cancer has spread to nearby lymph nodes.

Breast cancer cell defects linked with lymph node metastases

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Breast tumors that carry breast cancer stem and progenitor cells with mutations in specific oncogenes are significantly more likely than other breast cancers to metastasize to the lymph nodes, researchers reported.

Breast cancer prognosis more accurate when lymph nodes examined

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After a breast cancer operation, the removed tumor is always examined, as its subtype can provide an indication of how aggressive the disease is.

Nonsentinel lymph nodes key melanoma prognostic factor

Nonsentinel lymph nodes key melanoma prognostic factor

Subclassification of melanoma by NSLN tumor status suggested that positivity is a significant prognostic factor in patients with advanced melanoma.

SPECT/CT Associated With Improved Survival in Melanoma

SPECT/CT Associated With Improved Survival in Melanoma

SPECT/CT-aided sentinel lymph node excision improves detection of metastases, outcome.

Sentinel node biopsy safe for vulvar squamous cell cancer

Sentinel node biopsy safe for vulvar squamous cell cancer

Sentinel lymph node biopsy may be used in place of inguinal femoral lymphadenectomy.

Tumor-infiltrating lymphocyte grade IDs melanoma survival

Tumor-infiltrating lymphocyte grade IDs melanoma survival

TIL is an independent predictor of sentinel lymph node status and survival in cutaneous melanoma.

Coping With Lymphedema

Coping With Lymphedema

After lymph node removal, painful swelling may result. This fact sheet educates patients about how to manage symptoms.

Occult Positive Axillary Nodes in Breast CA Don't Worsen Survival

Occult Positive Axillary Nodes in Breast CA Don't Worsen Survival

Despite having been treated with negative-node protocols, no adverse effect in early-stage disease

Activities, Smoking Affect Lymph Node Involvement in Melanoma

Activities, Smoking Affect Lymph Node Involvement in Melanoma

Node size, volume, and number affected in patients with a history of invasive cutaneous melanoma

The Inside Edge, Sept 2009

A collection of recent articles from the medical literature discuss surgically removing and evaluating an increasing number of lymph nodes in patients with colorectal cancer; Black women with breast cancer have a greater chance of dying from the disease than white women; chemotherapy plus radiotherapy with or without resection (preferably lobectomy) are options for patients with stage IIIA (N2) non-small cell lung cancer; respecting the patient's preferences for treatment is a key component of high quality end of life care; and frankincense oil could prove a useful gift in the treatment of bladder cancer

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