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LUPRON DEPOT 7.5mg
Prostate and other male cancers
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Drug Name:

LUPRON DEPOT 7.5mg Rx

Generic Name and Formulations:
Leuprolide acetate 7.5mg; depot susp for IM inj.

Company:
AbbVie

Therapeutic Use:

Indications for LUPRON DEPOT 7.5mg:

Palliative treatment of advanced prostatic carcinoma.

Adult:

7.5mg IM once a month. Rotate inj site.

Children:

Not applicable.

Contraindications:

Pregnancy (Cat.X).

Warnings/Precautions:

Metastatic vertebral lesions. Urinary obstruction. Monitor serum testosterone, PSA, acid phosphatase. Increased risk of diabetes, MI, sudden cardiac death, stroke; monitor blood glucose, HbA1c, and for signs/symptoms of CVD during therapy. History of seizures. Risk of QT prolongation: long-term androgen deprivation therapy, congenital long QT syndrome, electrolyte abnormalities, or CHF. Correct and monitor electrolyte abnormalities; consider monitoring ECGs. Instruct patient on correct self administration. Nursing mothers: not recommended.

Interactions:

Concomitant antiarrhythmics may prolong the QT interval.

See Also:

LUPRON DEPOT-3 MONTH 22.5mg

LUPRON DEPOT-4 MONTH 30mg

LUPRON DEPOT-6 MONTH 45mg

Pharmacological Class:

GnRH analogue.

Adverse Reactions:

Hot flashes/sweats, inj site reaction, initial worsening of signs/symptoms (eg, bone pain, urinary tract obstruction, hematuria), edema, GI disorders, pain, cardiovascular events, CNS and antiandrogenic effects, asthenia, testicular atrophy, urinary disorders, spinal cord compression; hyperglycemia, anaphylactoid, photosensitivity.

How Supplied:

Depot kit—1 (prefilled dual-chamber syringe w. supplies)

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