Lung Cancer

Adjuvant Durvalumab Therapy May Prolong Progression-free Survival in NSCLC

Adjuvant Durvalumab Therapy May Prolong Progression-free Survival in NSCLC

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Patients with stage III NSCLC have a poor median PFS of 8 months despite achieving a good response to the current standard of care of platinum-based double chemotherapy with concurrent radiotherapy.

E-Cigarettes Increase BP, Heart Rate, Arterial Stiffness

E-Cigarettes Increase BP, Heart Rate, Arterial Stiffness

Significant increases seen in heart rate and arterial stiffness were observed in the first 30 minutes after smoking electronic-cigarette containing nicotine.

Cannabis Reduces Response Rate to Immunotherapy for Cancer

Cannabis Reduces Response Rate to Immunotherapy for Cancer

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Investigators report that administering cannabis to patients with cancer undergoing immunotherapy was found to lower the response rate to therapy but had no effect on PFS or OS, in an oral presentation at ESMO 2017 Congress.

Eligibility Criteria a Barrier to Lung Cancer Clinical Trial Participation

Eligibility Criteria a Barrier to Lung Cancer Clinical Trial Participation

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An investigation into the challenges of lung cancer clinical trials found that despite a lack of participants being detrimental to successful trial completion, clinical trials are trending toward increasing their eligibility criteria, making it more difficult to accrue enough eligible participants.

Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges

Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges

[Lung Cancer: Targets and Therapy] Chronic obstructive pulmonary disease and lung cancer share a common etiological factor and usually coexist in everyday clinical practice.

Vitamin B6 and B12 Supplements May Up Risk of Lung Cancer in Men

Vitamin B6 and B12 Supplements May Up Risk of Lung Cancer in Men

Vitamin B intake appears to be related to lung cancer risk, but only for men or male smokers.

Depth of Response Shows Potential as Clinical Outcome Measure in NSCLC

Depth of Response Shows Potential as Clinical Outcome Measure in NSCLC

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A retrospective analysis showed an association between depth of response (DepOR) and greater overall survival and longer progression-free survival.

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

[Lung Cancer: Targets and Therapy] This research reviews the current literature on psychosocial interventions in lung cancer, and discusses .

Anorexia-Cachexia in Non-Small Cell Lung Cancer Improved With Anamorelin

Anorexia-Cachexia in Non-Small Cell Lung Cancer Improved With Anamorelin

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Data from 5 phase 2/3 studies demonstrate improved weight and body mass in patients with NSCLC receiving anamorelin.

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

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A study on a cohort of women enrolled in the WHI-OS shows that those with a history of periodontal disease had a higher risk for developing some cancers.

Undergoing CT Lung Cancer Screening May Motivate Quit Attempts in Persons at High Risk

Undergoing CT Lung Cancer Screening May Motivate Quit Attempts in Persons at High Risk

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Contrary to some concerns, persons at high risk for lung cancer who undergo CT lung scans are more likely to attempt smoking cessation regardless of their test results compared with unscreened persons.

Risk of Lung Cancer Increases With Diets Higher in Saturated Fats

Risk of Lung Cancer Increases With Diets Higher in Saturated Fats

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A recent study demonstrated that eating a diet high in saturated fats and low in polyunsaturated fats may increase a person's risk of developing lung cancer.

Survival Predictions for NSCLC Accurate With the Lung Cancer Prognostic Index

Survival Predictions for NSCLC Accurate With the Lung Cancer Prognostic Index

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The Lung Cancer Prognostic Index (LCPI) provides additional relevant prognostic data for patients with NSCL and may lead to better outcomes.

Acupuncture May Improve Fatigue in Patients with Lung Cancer

Acupuncture May Improve Fatigue in Patients with Lung Cancer

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Acupuncture was found to improve cancer-related fatigue in patients with lung cancer in as little as 2 weeks, according to results of a double-blind randomized clinical study.

Rates at Some Milestones May Indicate Clinical Trial Results for Immunotherapeutics

Rates at Some Milestones May Indicate Clinical Trial Results for Immunotherapeutics

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An analysis of rates at certain milestones in clinical trials of treatments for mNSCLC suggests these rates reflect end point results for immunotherapies vs targeted and conventional therapies.

Study Questions Safety of E-cigarettes vs Regular Tobacco Cigarettes

Study Questions Safety of E-cigarettes vs Regular Tobacco Cigarettes

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E-cigarettes used with nicotine-based liquid have the same potential to produce cancer-causing DNA damage as unfiltered regular cigarettes.

New Study Questions Standard Dosage for Treating Metastatic Non-Small Cell Lung Cancer

New Study Questions Standard Dosage for Treating Metastatic Non-Small Cell Lung Cancer

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Doses May Be Adjusted for Treating NSCLC Patients

Superior Tolerability, Efficacy With Alectinib in Treatment-Naïve ALK-poistive NSCLC

Superior Tolerability, Efficacy With Alectinib in Treatment-Naïve ALK-poistive NSCLC

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Phase 3 clinical trial results show fewer adverse effects and longer survival with alectinib compared with crizotinib in patients with treatment-naïve ALK-positive NSCLC.

Navigating the Non-small Cell Lung Cancer Patient: CT Lung Cancer Screening Development

Navigating the Non-small Cell Lung Cancer Patient: CT Lung Cancer Screening Development

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Developing a lung cancer screening program involves a number of challenges, including identifying patients in need of screening, patient follow-up, and community support.

Improved Outcomes in Lung Cancer With Hyperfractionated Chemoradiation Therapy

Improved Outcomes in Lung Cancer With Hyperfractionated Chemoradiation Therapy

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Twice daily radiation therapy with chemotherapy may improve survival times in patients with some advanced head and neck cancers, a new study confirms.

Filtered Cigarettes May Increase Rates of Lung Adenocarcinoma

Filtered Cigarettes May Increase Rates of Lung Adenocarcinoma

The design of cigarette filters with ventilation is associated with rising adenocarcinoma rates, research indicates.

Neurocognitive Function Impacts Health-Related QOL in Advanced Lung Cancer

Neurocognitive Function Impacts Health-Related QOL in Advanced Lung Cancer

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Study finds a correlation between various measures of neurocognitive function and health utility scores.

Patient Navigators Found to Boost Lung Cancer Screening Rates

Patient Navigators Found to Boost Lung Cancer Screening Rates

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Counseling current smokers and helping to direct their care may reduce lung cancer mortality in underserved low-income populations.

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

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A combination treatment of mitogen-activated protein kinase MEK inhibitor and chemotherapy did not improve progression-free survival in patients with advanced lung cancer caused by a KRAS gene mutation.

Influenza Vaccination Increases Toxicity in PD-1/PD-L1 Immunotherapy Blockade for Lung Cancer

Influenza Vaccination Increases Toxicity in PD-1/PD-L1 Immunotherapy Blockade for Lung Cancer

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Seasonal influenza vaccination was associated with increased rates of immunologic toxicity in patients with lung cancer receiving PD-1/PD-L1 immunotherapy blockade.

Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab

Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab

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A significantly higher 5-year survival rate was seen in a small subset of patients with NSCLC treated with nivolumab.

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

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Regular infusions of high doses of vitamin C safely increased cancer cell sensitivity to treatment in patients with brain and lung cancers.

Pembrolizumab May Help Combat Mesothelioma

Pembrolizumab May Help Combat Mesothelioma

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Checkpoint inhibitor pembrolizumab appears well-tolerated with antitumor activity in patients with malignant pleural mesothelioma.

Radiation Therapy for Locally Advanced NSCLC Linked to Cardiac Events

Radiation Therapy for Locally Advanced NSCLC Linked to Cardiac Events

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Risk for cardiac events linked to RT for locally advanced NSCLC, especially in patients with a history of cardiac disease or receiving higher RT doses.

CTCs Promising as Biomarker to Identify Lung Cancer Recurrence

CTCs Promising as Biomarker to Identify Lung Cancer Recurrence

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Prospective pilot study demonstrates accuracy of circulating tumor cells as a biomarker indicating lung cancer recurrence.

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