Lung Cancer

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

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Researchers in Montreal presented results of a study on the effects of using a pivot nurse in oncology (PNO) on continuity of care, outcomes, and quality of life for patients with lung cancer at the 2018 European Lung Cancer Congress.

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

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Analysis of data from more than 1 million people demonstrates the value of tobacco-use data in tailoring public health programs to prevalence of smokers in local populations.

Vaping May Induce Severe, Negative Effects on Lung Health

Vaping May Induce Severe, Negative Effects on Lung Health

Researchers presented the preliminary results from an ongoing randomized, crossover study evaluating the cardiorespiratory effects of e-cigarettes.

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

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Researchers conducted a case-control study that examined independent predictive factors of lung cancer in patients with chronic obstructive pulmonary disease.

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

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The panel assembled and updated the above guidelines and recommendations regarding lung cancer screening and low-dose CT screening programs.

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

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In a quasi-experimental pre-post study, researchers demonstrate the efficacy of the SEE-ACBT rehabilitation method on health-related and cost outcomes in patients with NSCLC who underwent curative lung resection.

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

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Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide, crotonaldehyde up

E-Cigarette Vapors Found to Contain Toxic Metals

E-Cigarette Vapors Found to Contain Toxic Metals

Study finds metals, including lead, leak from e-cigarette heating coils into inhaled aerosols

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

[Cancer Management and Research] The presence of comorbidities is thought to play a significant role in the decision to treat patients with NSCLC, and this impacts survival.

Exercise, Fitness Significantly Decrease After Advanced Lung Cancer Diagnosis

Exercise, Fitness Significantly Decrease After Advanced Lung Cancer Diagnosis

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Using MVIC and 6MWT, researchers sought to determine if patients' exercise behaviors changed after a diagnosis of advanced lung cancer.

Exercise Before Lung Cancer Surgery Greatly Reduces Complications

Exercise Before Lung Cancer Surgery Greatly Reduces Complications

Researchers conducted a systematic literature search to identify studies investigating the effectiveness of preoperative exercise on outcomes among oncology patients undergoing surgery.

Efficacy and Safety of COX-2 Inhibitors for Advanced Non-small-cell Lung Cancer With Chemotherapy: A Meta-analysis

Efficacy and Safety of COX-2 Inhibitors for Advanced Non-small-cell Lung Cancer With Chemotherapy: A Meta-analysis

[OncoTargets and Therapy] This meta-analysis assesses the efficacy and safety profile of COX-2 inhibitors in patients with advanced non-small-cell lung cancer.

Lung Cancer Screening: Risk-Targeting Approach vs NLST Eligibility Criteria

Lung Cancer Screening: Risk-Targeting Approach vs NLST Eligibility Criteria

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In a review of data from the NLST, researchers sought to determine if a risk-targeting approach would more efficiently select high-risk persons for lung cancer screening than the eligibility criteria defined by the NLST.

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-based chemotherapy agents for lung cancer may increase the risk for thromboembolism.

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

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Qualitative risk statements of malignancy for indeterminate pulmonary nodules are imprecise, highly variable, and should be replaced by a standard scale.

Lung Cancer Screening More Efficient for Those at Higher Risk

Lung Cancer Screening More Efficient for Those at Higher Risk

Initial screens were least effective and least efficient for veterans with lowest lung cancer risk, according to this study.

Nearly One Third of Veterans Report Current Tobacco Use

Nearly One Third of Veterans Report Current Tobacco Use

Researchers found that nearly one third of veterans reported current use of a tobacco product, with cigarettes being most frequently used.

Risk-based lung cancer screening may prevent more deaths than current guidelines

1. In terms of early lung cancer death per individual screened, targeting lung cancer mortality risk may improve lung cancer screening efficiency. 2. However, the increases in efficiency were attenuated when measured by life-years, quality-adjusted life-years (QALYs), and cost-effectiveness. Evidence Rating Level: 2 (Good)          Study Rundown: Current guidelines for lung cancer screening using low-dose computed []

Osimertinib improves progression-free survival in EGFR-mutated non-small-cell lung cancer: The FLAURA trial

1. Osimertinib demonstrated a significantly longer duration of progression-free survival compared to standard of care epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKI) in patients with untreated EGFR-mutated locally-advanced or metastatic non-small-cell lung cancer (NSCLC). 2. Osimertinib treated patients had fewer grade 3 or higher adverse events compared to patients treated with standard EGFR-TKI therapy. []

Monetary Incentives Improve Quit Attempts in Mentally Ill Smokers

Monetary Incentives Improve Quit Attempts in Mentally Ill Smokers

Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.

Pain Tolerance Lower in Abstinent Smokers Before, Following Surgery

Pain Tolerance Lower in Abstinent Smokers Before, Following Surgery

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Abstinent smokers may have reduced preoperative pain tolerance and increased postoperative opioid use compared with nonsmokers.

Smoking Quit Rates Not Improved With Use of Pharmaceutical Cessation Aids

Smoking Quit Rates Not Improved With Use of Pharmaceutical Cessation Aids

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Using data from the TUS-CPS, researchers sought to determine the effect of pharmaceutical smoking cessation aids on long-term quit rates among patients who smoke tobacco.

Surgery May Be Superior to Stereotactic Body RT for Early Stage Non-small Cell Lung Cancer

Surgery May Be Superior to Stereotactic Body RT for Early Stage Non-small Cell Lung Cancer

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SBRT provides excellent local control and an adequate safety profile, but there is a lack of data comparing SBRT to resection among patients eligible for surgery.

Nab-paclitaxel/carboplatin Induction in Squamous NSCLC: Longitudinal Quality of Life While on Chemotherapy

Nab-paclitaxel/carboplatin Induction in Squamous NSCLC: Longitudinal Quality of Life While on Chemotherapy

[Lung Cancer: Targets and Therapy] Researchers examine the affect of first-line nab-paclitaxel plus carboplatinon QoL for patients with advanced non-small cell lung cancer.

Gefitinib Adjuvant Therapy Prolonged Disease-Free Survival in EGFR-Mutant NSCLC

Gefitinib Adjuvant Therapy Prolonged Disease-Free Survival in EGFR-Mutant NSCLC

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Results of this randomized, phase 3 study comparing oral gefitinib with IV vinorelbine plus cisplatin revealed the effect of these regimens on disease-free survival in patients with exon 19 deletion or exon Leu585Arg NSCLC.

Liquid Biopsies: An Emerging and Versatile Monitoring Modality in Lung Cancer

Liquid Biopsies: An Emerging and Versatile Monitoring Modality in Lung Cancer

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In lung cancer, it is critical to evaluate the resistance mechanisms so appropriate treatment can be administered.

Alectinib Granted FDA Approval as First-line Therapy for <i>ALK</i>-positive NSCLC

Alectinib Granted FDA Approval as First-line Therapy for ALK-positive NSCLC

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Approval was based on results from ALEX, for which researchers randomly assigned 303 patients with ALK-positive NSCLC not previously treated with systemic therapy to receive alectinib or crizotinib.

Cause of Death More Likely to Be Lung Cancer Than AIDS in Smokers With HIV

Cause of Death More Likely to Be Lung Cancer Than AIDS in Smokers With HIV

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Populating a microsimulation of model of HIV disease, researchers investigated the the likelihood of lung cancer-related morbidity and mortality among patients with HIV who smoke, based on smoking intensity.

Netupitant Plus Palonosetron Safe, Effective Strategy for CINV in Lung Cancer

Netupitant Plus Palonosetron Safe, Effective Strategy for CINV in Lung Cancer

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A post-hoc analysis of 2 clinical trials was conducted to determine the safety and effectiveness of NEPA for managing CINV in patients with lung cancer who received platinum-based chemotherapy.

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