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Lung Cancer News & Features

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Two phase 3 studies reveal the clinical benefit, safety profile, and overall survival of nivolumab and docetaxel for patients with squamous and nonsquamous NSCLC.

Osimertinib in the Treatment of Non-small Cell Lung Cancer: Design, Development and Place in Therapy

Osimertinib in the Treatment of Non-small Cell Lung Cancer: Design, Development and Place in Therapy

[Lung cancer: Targets and Therapy] This research examines clinical data from Phase I-III trials of osimertinib, discusses mechanisms of resistance to osimertinib, and provides an outlook for the use of osimertinib and novel therapeutic combinations to improve EGFR-mutated NSCLC outcomes.

Radiation Prior to Chemotherapy Prolongs Progression-Free Survival in NSCLC

Radiation Prior to Chemotherapy Prolongs Progression-Free Survival in NSCLC

Researchers present findings of a phase 2 study that compared PFS when SBRT is administered prior to maintenance chemotherapy in patients with limited metastatic NSCLC vs chemotherapy alone. Data was presented at ASTRO 59th Annual Meeting.

Spontaneous Tumor Lysis Syndrome in Recently Diagnosed Small Cell Lung Cancer

Spontaneous Tumor Lysis Syndrome in Recently Diagnosed Small Cell Lung Cancer

This case demonstrates that, although rare, spontaneous TLS can occur even in the absence of chemotherapy, and a high index of suspicion for the effect should be maintained when patients with malignancies demonstrate the classic symptom of laboratory abnormalities.

Adjuvant Durvalumab Therapy May Prolong Progression-free Survival in NSCLC

Adjuvant Durvalumab Therapy May Prolong Progression-free Survival in NSCLC

Patients with stage III NSCLC have a poor median PFS of 8 months despite achieving a good response to the current standard of care of platinum-based double chemotherapy with concurrent radiotherapy.

E-Cigarettes Increase BP, Heart Rate, Arterial Stiffness

E-Cigarettes Increase BP, Heart Rate, Arterial Stiffness

Significant increases seen in heart rate and arterial stiffness were observed in the first 30 minutes after smoking electronic-cigarette containing nicotine.

Eligibility Criteria a Barrier to Lung Cancer Clinical Trial Participation

Eligibility Criteria a Barrier to Lung Cancer Clinical Trial Participation

An investigation into the challenges of lung cancer clinical trials found that despite a lack of participants being detrimental to successful trial completion, clinical trials are trending toward increasing their eligibility criteria, making it more difficult to accrue enough eligible participants.

Vitamin B6 and B12 Supplements May Up Risk of Lung Cancer in Men

Vitamin B6 and B12 Supplements May Up Risk of Lung Cancer in Men

Vitamin B intake appears to be related to lung cancer risk, but only for men or male smokers.

Depth of Response Shows Potential as Clinical Outcome Measure in NSCLC

Depth of Response Shows Potential as Clinical Outcome Measure in NSCLC

A retrospective analysis showed an association between depth of response (DepOR) and greater overall survival and longer progression-free survival.

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

[Lung Cancer: Targets and Therapy] This research reviews the current literature on psychosocial interventions in lung cancer, and discusses .

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