Hope, Optimism Reduce Psychological Distress in Advanced Cancer

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.

Evolving Role of Radiation Therapy in the Treatment of Mesothelioma

Evolving Role of Radiation Therapy in the Treatment of Mesothelioma

Research into the potential of radiation therapy in the management of mesothelioma may improve the prognosis, and possibly extend progression-free survival, for patients with this incurable cancer.

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Researchers in Montreal presented results of a study on the effects of using a pivot nurse in oncology (PNO) on continuity of care, outcomes, and quality of life for patients with lung cancer at the 2018 European Lung Cancer Congress.

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

Analysis of data from more than 1 million people demonstrates the value of tobacco-use data in tailoring public health programs to prevalence of smokers in local populations.

Vaping May Induce Severe, Negative Effects on Lung Health

Vaping May Induce Severe, Negative Effects on Lung Health

Researchers presented the preliminary results from an ongoing randomized, crossover study evaluating the cardiorespiratory effects of e-cigarettes.

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

Researchers conducted a case-control study that examined independent predictive factors of lung cancer in patients with chronic obstructive pulmonary disease.

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

The panel assembled and updated the above guidelines and recommendations regarding lung cancer screening and low-dose CT screening programs.

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

In a quasi-experimental pre-post study, researchers demonstrate the efficacy of the SEE-ACBT rehabilitation method on health-related and cost outcomes in patients with NSCLC who underwent curative lung resection.

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide, crotonaldehyde up

E-Cigarette Vapors Found to Contain Toxic Metals

E-Cigarette Vapors Found to Contain Toxic Metals

Study finds metals, including lead, leak from e-cigarette heating coils into inhaled aerosols

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

[Cancer Management and Research] The presence of comorbidities is thought to play a significant role in the decision to treat patients with NSCLC, and this impacts survival.

Exercise, Fitness Significantly Decrease After Advanced Lung Cancer Diagnosis

Exercise, Fitness Significantly Decrease After Advanced Lung Cancer Diagnosis

Using MVIC and 6MWT, researchers sought to determine if patients' exercise behaviors changed after a diagnosis of advanced lung cancer.

Exercise Before Lung Cancer Surgery Greatly Reduces Complications

Exercise Before Lung Cancer Surgery Greatly Reduces Complications

Researchers conducted a systematic literature search to identify studies investigating the effectiveness of preoperative exercise on outcomes among oncology patients undergoing surgery.

Efficacy and Safety of COX-2 Inhibitors for Advanced Non-small-cell Lung Cancer With Chemotherapy: A Meta-analysis

Efficacy and Safety of COX-2 Inhibitors for Advanced Non-small-cell Lung Cancer With Chemotherapy: A Meta-analysis

[OncoTargets and Therapy] This meta-analysis assesses the efficacy and safety profile of COX-2 inhibitors in patients with advanced non-small-cell lung cancer.

Lung Cancer Screening: Risk-Targeting Approach vs NLST Eligibility Criteria

Lung Cancer Screening: Risk-Targeting Approach vs NLST Eligibility Criteria

In a review of data from the NLST, researchers sought to determine if a risk-targeting approach would more efficiently select high-risk persons for lung cancer screening than the eligibility criteria defined by the NLST.

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-based chemotherapy agents for lung cancer may increase the risk for thromboembolism.

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

Qualitative risk statements of malignancy for indeterminate pulmonary nodules are imprecise, highly variable, and should be replaced by a standard scale.

PSPT vs IMRT: Radiation Exposure Reduced in Heart Only

PSPT vs IMRT: Radiation Exposure Reduced in Heart Only

PSPT significantly reduced radiation exposure to the heart, but no differences were observed between PSPT and IMRT for the lung or esophagus.

Lung Cancer Screening More Efficient for Those at Higher Risk

Lung Cancer Screening More Efficient for Those at Higher Risk

Initial screens were least effective and least efficient for veterans with lowest lung cancer risk, according to this study.

Nearly One Third of Veterans Report Current Tobacco Use

Nearly One Third of Veterans Report Current Tobacco Use

Researchers found that nearly one third of veterans reported current use of a tobacco product, with cigarettes being most frequently used.

Risk-based lung cancer screening may prevent more deaths than current guidelines

1. In terms of early lung cancer death per individual screened, targeting lung cancer mortality risk may improve lung cancer screening efficiency. 2. However, the increases in efficiency were attenuated when measured by life-years, quality-adjusted life-years (QALYs), and cost-effectiveness. Evidence Rating Level: 2 (Good)          Study Rundown: Current guidelines for lung cancer screening using low-dose computed []

Osimertinib improves progression-free survival in EGFR-mutated non-small-cell lung cancer: The FLAURA trial

1. Osimertinib demonstrated a significantly longer duration of progression-free survival compared to standard of care epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKI) in patients with untreated EGFR-mutated locally-advanced or metastatic non-small-cell lung cancer (NSCLC). 2. Osimertinib treated patients had fewer grade 3 or higher adverse events compared to patients treated with standard EGFR-TKI therapy. []

Monetary Incentives Improve Quit Attempts in Mentally Ill Smokers

Monetary Incentives Improve Quit Attempts in Mentally Ill Smokers

Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.

Pain Tolerance Lower in Abstinent Smokers Before, Following Surgery

Pain Tolerance Lower in Abstinent Smokers Before, Following Surgery

Abstinent smokers may have reduced preoperative pain tolerance and increased postoperative opioid use compared with nonsmokers.

Smoking Quit Rates Not Improved With Use of Pharmaceutical Cessation Aids

Smoking Quit Rates Not Improved With Use of Pharmaceutical Cessation Aids

Using data from the TUS-CPS, researchers sought to determine the effect of pharmaceutical smoking cessation aids on long-term quit rates among patients who smoke tobacco.

Surgery May Be Superior to Stereotactic Body RT for Early Stage Non-small Cell Lung Cancer

Surgery May Be Superior to Stereotactic Body RT for Early Stage Non-small Cell Lung Cancer

SBRT provides excellent local control and an adequate safety profile, but there is a lack of data comparing SBRT to resection among patients eligible for surgery.

Nab-paclitaxel/carboplatin Induction in Squamous NSCLC: Longitudinal Quality of Life While on Chemotherapy

Nab-paclitaxel/carboplatin Induction in Squamous NSCLC: Longitudinal Quality of Life While on Chemotherapy

[Lung Cancer: Targets and Therapy] Researchers examine the affect of first-line nab-paclitaxel plus carboplatinon QoL for patients with advanced non-small cell lung cancer.

Gefitinib Adjuvant Therapy Prolonged Disease-Free Survival in EGFR-Mutant NSCLC

Gefitinib Adjuvant Therapy Prolonged Disease-Free Survival in EGFR-Mutant NSCLC

Results of this randomized, phase 3 study comparing oral gefitinib with IV vinorelbine plus cisplatin revealed the effect of these regimens on disease-free survival in patients with exon 19 deletion or exon Leu585Arg NSCLC.

Liquid Biopsies: An Emerging and Versatile Monitoring Modality in Lung Cancer

Liquid Biopsies: An Emerging and Versatile Monitoring Modality in Lung Cancer

In lung cancer, it is critical to evaluate the resistance mechanisms so appropriate treatment can be administered.

Alectinib Granted FDA Approval as First-line Therapy for ALK-positive NSCLC

Alectinib Granted FDA Approval as First-line Therapy for ALK-positive NSCLC

Approval was based on results from ALEX, for which researchers randomly assigned 303 patients with ALK-positive NSCLC not previously treated with systemic therapy to receive alectinib or crizotinib.

Cause of Death More Likely to Be Lung Cancer Than AIDS in Smokers With HIV

Cause of Death More Likely to Be Lung Cancer Than AIDS in Smokers With HIV

Populating a microsimulation of model of HIV disease, researchers investigated the the likelihood of lung cancer-related morbidity and mortality among patients with HIV who smoke, based on smoking intensity.

Netupitant Plus Palonosetron Safe, Effective Strategy for CINV in Lung Cancer

Netupitant Plus Palonosetron Safe, Effective Strategy for CINV in Lung Cancer

A post-hoc analysis of 2 clinical trials was conducted to determine the safety and effectiveness of NEPA for managing CINV in patients with lung cancer who received platinum-based chemotherapy.

Yoga Programs May Improve Quality of Life for Patients with NSCLC and Their Caregivers

Yoga Programs May Improve Quality of Life for Patients with NSCLC and Their Caregivers

This study evaluated the feasibility and potential efficacy of a yoga intervention for patients with NSCLC and their caregivers.

Language Barrier, Patient Ethnicity Do Not Delay Hospital Treatment in NSCLC

Language Barrier, Patient Ethnicity Do Not Delay Hospital Treatment in NSCLC

Impact of language barrier and patient ethnicity on time interval from diagnosis to treatment for patients with NSCLC was measured at a public hospital and a private hospital.

A Case of Immunotherapy-Induced Myocarditis Concomitant to MG in Lung Cancer

A Case of Immunotherapy-Induced Myocarditis Concomitant to MG in Lung Cancer

In this case, a female patient with advanced lung cancer experiences a rare episode of nivolumab-induced Herzmyasthenie, emphasizing the need to be aware of the potential for rapid myocarditis concomitant with MG in patients undergoing treatment with anti-PD-1 monoclonal antibodies.

Novel Predictive Model More Effectively Identifies Risk for Lung Cancer

Novel Predictive Model More Effectively Identifies Risk for Lung Cancer

PanCan study results demonstrate the effectiveness of a novel predictive model in identifying risk of lung cancer in patients who do not meet the screening criteria of other models, including those used in the NLST.

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Two phase 3 studies reveal the clinical benefit, safety profile, and overall survival of nivolumab and docetaxel for patients with squamous and nonsquamous NSCLC.

Osimertinib in the Treatment of Non-small Cell Lung Cancer: Design, Development and Place in Therapy

Osimertinib in the Treatment of Non-small Cell Lung Cancer: Design, Development and Place in Therapy

[Lung cancer: Targets and Therapy] This research examines clinical data from Phase I-III trials of osimertinib, discusses mechanisms of resistance to osimertinib, and provides an outlook for the use of osimertinib and novel therapeutic combinations to improve EGFR-mutated NSCLC outcomes.

Combining Radiation, Immunotherapy: An Emerging Challenge for Oncology Nursing

Combining Radiation, Immunotherapy: An Emerging Challenge for Oncology Nursing

Combining radiotherapy and immunotherapy has shown early promise against some advanced cancers, but oncology nurses need to be wary of potential overlapping toxicity profiles from each of these treatment modalities.

Radiation Prior to Chemotherapy Prolongs Progression-Free Survival in NSCLC

Radiation Prior to Chemotherapy Prolongs Progression-Free Survival in NSCLC

Researchers present findings of a phase 2 study that compared PFS when SBRT is administered prior to maintenance chemotherapy in patients with limited metastatic NSCLC vs chemotherapy alone. Data was presented at ASTRO 59th Annual Meeting.

Spontaneous Tumor Lysis Syndrome in Recently Diagnosed Small Cell Lung Cancer

Spontaneous Tumor Lysis Syndrome in Recently Diagnosed Small Cell Lung Cancer

This case demonstrates that, although rare, spontaneous TLS can occur even in the absence of chemotherapy, and a high index of suspicion for the effect should be maintained when patients with malignancies demonstrate the classic symptom of laboratory abnormalities.

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

Bevacizumab-awwb is a recombinant IgG1 monoclonal antibody that works by binding to vascular endothelial growth factor (VEGF) and inhibits angiogenesis.

Adjuvant Durvalumab Therapy May Prolong Progression-free Survival in NSCLC

Adjuvant Durvalumab Therapy May Prolong Progression-free Survival in NSCLC

Patients with stage III NSCLC have a poor median PFS of 8 months despite achieving a good response to the current standard of care of platinum-based double chemotherapy with concurrent radiotherapy.

E-Cigarettes Increase BP, Heart Rate, Arterial Stiffness

E-Cigarettes Increase BP, Heart Rate, Arterial Stiffness

Significant increases seen in heart rate and arterial stiffness were observed in the first 30 minutes after smoking electronic-cigarette containing nicotine.

Cannabis Reduces Response Rate to Immunotherapy for Cancer

Cannabis Reduces Response Rate to Immunotherapy for Cancer

Investigators report that administering cannabis to patients with cancer undergoing immunotherapy was found to lower the response rate to therapy but had no effect on PFS or OS, in an oral presentation at ESMO 2017 Congress.

Eligibility Criteria a Barrier to Lung Cancer Clinical Trial Participation

Eligibility Criteria a Barrier to Lung Cancer Clinical Trial Participation

An investigation into the challenges of lung cancer clinical trials found that despite a lack of participants being detrimental to successful trial completion, clinical trials are trending toward increasing their eligibility criteria, making it more difficult to accrue enough eligible participants.

Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges

Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges

[Lung Cancer: Targets and Therapy] Chronic obstructive pulmonary disease and lung cancer share a common etiological factor and usually coexist in everyday clinical practice.

Vitamin B6 and B12 Supplements May Up Risk of Lung Cancer in Men

Vitamin B6 and B12 Supplements May Up Risk of Lung Cancer in Men

Vitamin B intake appears to be related to lung cancer risk, but only for men or male smokers.

Depth of Response Shows Potential as Clinical Outcome Measure in NSCLC

Depth of Response Shows Potential as Clinical Outcome Measure in NSCLC

A retrospective analysis showed an association between depth of response (DepOR) and greater overall survival and longer progression-free survival.

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

[Lung Cancer: Targets and Therapy] This research reviews the current literature on psychosocial interventions in lung cancer, and discusses .

Anorexia-Cachexia in Non-Small Cell Lung Cancer Improved With Anamorelin

Anorexia-Cachexia in Non-Small Cell Lung Cancer Improved With Anamorelin

Data from 5 phase 2/3 studies demonstrate improved weight and body mass in patients with NSCLC receiving anamorelin.

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

A study on a cohort of women enrolled in the WHI-OS shows that those with a history of periodontal disease had a higher risk for developing some cancers.

Undergoing CT Lung Cancer Screening May Motivate Quit Attempts in Persons at High Risk

Undergoing CT Lung Cancer Screening May Motivate Quit Attempts in Persons at High Risk

Contrary to some concerns, persons at high risk for lung cancer who undergo CT lung scans are more likely to attempt smoking cessation regardless of their test results compared with unscreened persons.

Risk of Lung Cancer Increases With Diets Higher in Saturated Fats

Risk of Lung Cancer Increases With Diets Higher in Saturated Fats

A recent study demonstrated that eating a diet high in saturated fats and low in polyunsaturated fats may increase a person's risk of developing lung cancer.

Survival Predictions for NSCLC Accurate With the Lung Cancer Prognostic Index

Survival Predictions for NSCLC Accurate With the Lung Cancer Prognostic Index

The Lung Cancer Prognostic Index (LCPI) provides additional relevant prognostic data for patients with NSCL and may lead to better outcomes.

"Light" Cigarettes and Cancer Risk (Fact Sheet)

"Light" Cigarettes and Cancer Risk (Fact Sheet)

This fact sheet examines so-called "light" cigarettes, associated cancer risks, and tar yield ratings.

Acupuncture May Improve Fatigue in Patients with Lung Cancer

Acupuncture May Improve Fatigue in Patients with Lung Cancer

Acupuncture was found to improve cancer-related fatigue in patients with lung cancer in as little as 2 weeks, according to results of a double-blind randomized clinical study.

Rates at Some Milestones May Indicate Clinical Trial Results for Immunotherapeutics

Rates at Some Milestones May Indicate Clinical Trial Results for Immunotherapeutics

An analysis of rates at certain milestones in clinical trials of treatments for mNSCLC suggests these rates reflect end point results for immunotherapies vs targeted and conventional therapies.

Study Questions Safety of E-cigarettes vs Regular Tobacco Cigarettes

Study Questions Safety of E-cigarettes vs Regular Tobacco Cigarettes

E-cigarettes used with nicotine-based liquid have the same potential to produce cancer-causing DNA damage as unfiltered regular cigarettes.

Superior Tolerability, Efficacy With Alectinib in Treatment-Naïve ALK-poistive NSCLC

Superior Tolerability, Efficacy With Alectinib in Treatment-Naïve ALK-poistive NSCLC

Phase 3 clinical trial results show fewer adverse effects and longer survival with alectinib compared with crizotinib in patients with treatment-naïve ALK-positive NSCLC.

Navigating the Non-small Cell Lung Cancer Patient: CT Lung Cancer Screening Development

Navigating the Non-small Cell Lung Cancer Patient: CT Lung Cancer Screening Development

Developing a lung cancer screening program involves a number of challenges, including identifying patients in need of screening, patient follow-up, and community support.

Improved Outcomes in Lung Cancer With Hyperfractionated Chemoradiation Therapy

Improved Outcomes in Lung Cancer With Hyperfractionated Chemoradiation Therapy

Twice daily radiation therapy with chemotherapy may improve survival times in patients with some advanced head and neck cancers, a new study confirms.

Filtered Cigarettes May Increase Rates of Lung Adenocarcinoma

Filtered Cigarettes May Increase Rates of Lung Adenocarcinoma

The design of cigarette filters with ventilation is associated with rising adenocarcinoma rates, research indicates.

Neurocognitive Function Impacts Health-Related QOL in Advanced Lung Cancer

Neurocognitive Function Impacts Health-Related QOL in Advanced Lung Cancer

Study finds a correlation between various measures of neurocognitive function and health utility scores.

Patient Navigators Found to Boost Lung Cancer Screening Rates

Patient Navigators Found to Boost Lung Cancer Screening Rates

Counseling current smokers and helping to direct their care may reduce lung cancer mortality in underserved low-income populations.

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

A combination treatment of mitogen-activated protein kinase MEK inhibitor and chemotherapy did not improve progression-free survival in patients with advanced lung cancer caused by a KRAS gene mutation.

Influenza Vaccination Increases Toxicity in PD-1/PD-L1 Immunotherapy Blockade for Lung Cancer

Influenza Vaccination Increases Toxicity in PD-1/PD-L1 Immunotherapy Blockade for Lung Cancer

Seasonal influenza vaccination was associated with increased rates of immunologic toxicity in patients with lung cancer receiving PD-1/PD-L1 immunotherapy blockade.

Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab

Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab

A significantly higher 5-year survival rate was seen in a small subset of patients with NSCLC treated with nivolumab.

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

Regular infusions of high doses of vitamin C safely increased cancer cell sensitivity to treatment in patients with brain and lung cancers.

Pembrolizumab May Help Combat Mesothelioma

Pembrolizumab May Help Combat Mesothelioma

Checkpoint inhibitor pembrolizumab appears well-tolerated with antitumor activity in patients with malignant pleural mesothelioma.

Radiation Therapy for Locally Advanced NSCLC Linked to Cardiac Events

Radiation Therapy for Locally Advanced NSCLC Linked to Cardiac Events

Risk for cardiac events linked to RT for locally advanced NSCLC, especially in patients with a history of cardiac disease or receiving higher RT doses.

CTCs Promising as Biomarker to Identify Lung Cancer Recurrence

CTCs Promising as Biomarker to Identify Lung Cancer Recurrence

Prospective pilot study demonstrates accuracy of circulating tumor cells as a biomarker indicating lung cancer recurrence.

Free Lung Cancer Screening Findings Support Continual Screenings in High-Risk Populations

Free Lung Cancer Screening Findings Support Continual Screenings in High-Risk Populations

A free lung cancer screening program in Augusta, Georgia, found more than double the lung cancer rate of previous screenings.

Shared Decision-making Visits Improved Comfort With Lung Cancer Screening Decisions

Shared Decision-making Visits Improved Comfort With Lung Cancer Screening Decisions

Patients were more comfortable with their decisions about lung cancer screening after a shared decision-making visit.

Kidney Cancer Metastases in Lung May Hide Undiagnosed Primary Lung Cancer

Kidney Cancer Metastases in Lung May Hide Undiagnosed Primary Lung Cancer

Patients with metastatic kidney cancer may also have an primary lung cancer that has gone gone undiagnosed.

Nasal Biomarker in Smokers Could Predict Lung Cancer

Nasal Biomarker in Smokers Could Predict Lung Cancer

Novel diagnostic test determines whether suspicious lung lesions or nodules are malignant disease from a sample obtained via nasal swab.

Proportion of Never-Smokers With NSCLC Is on the Rise

Proportion of Never-Smokers With NSCLC Is on the Rise

A study of a large, diverse patient population appears to show an increasing incidence of lung cancer in patients who have never smoked tobacco.

Patients with Lung Cancer Do Not Benefit from Statins

Patients with Lung Cancer Do Not Benefit from Statins

Statins provide no benefits, or adverse effects, in patients with lung cancer, according to a phase 3 trial.

Risk of Lung Cancer Increases After Radiation for Breast Cancer

Risk of Lung Cancer Increases After Radiation for Breast Cancer

Treatment with radiation therapy for invasive breast cancer may place East Asian women at a greater risk of developing second primary lung cancer (SPLC).

NSCLC: Pathway Navigation Program Lowers Costs of Care

NSCLC: Pathway Navigation Program Lowers Costs of Care

A clinical pathways navigation program for patients with non-small cell lung cancer significantly reduced cost of care while preserving clinical outcomes.

SCLC: No Benefit from Pravastatin When Added to First-line Chemo

SCLC: No Benefit from Pravastatin When Added to First-line Chemo

The addition of pravastatin to first-line chemotherapy did not improve overall survival or progression-free survival in patients with small-cell lung cancer.

FDA Grants Priority Review to Ceritinib for First-line Treatment of ALK+ NSCLC

FDA Grants Priority Review to Ceritinib for First-line Treatment of ALK+ NSCLC

Ceritinib has been granted Priority Review as a first-line treatment for patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer.

E-cigarettes and Replacement Nicotine Therapy Safer Than Tobacco Use

E-cigarettes and Replacement Nicotine Therapy Safer Than Tobacco Use

E-cigarettes and replacement nicotine therapy deposit fewer harmful chemicals in the body that smoking.

Elderly with NSCLC Can Tolerate Aggressive Radiation Therapy Treatments

Elderly with NSCLC Can Tolerate Aggressive Radiation Therapy Treatments

Elderly with NSCLC have lower incidence of esophagitis, can tolerate aggressive radiation therapy.

Annual Screening of High-Risk Smokers Only More Cost-effective Than Current Methods

Annual Screening of High-Risk Smokers Only More Cost-effective Than Current Methods

Annual lung cancer screening of only high-risk smokers more cost-effective than current methods.

Lung Cancer Screening Rates Low Among Present and Former Smokers

Lung Cancer Screening Rates Low Among Present and Former Smokers

Researchers estimate that out of the 6.8 million current and former smokers eligible for lung cancer screening in 2015, only a fraction received it.

New Study Shows Standard of Care for NSCLC Patients Leads to Improved Overall Survival

New Study Shows Standard of Care for NSCLC Patients Leads to Improved Overall Survival

There are a growing number of NSCLC patients with advanced disease who are opting to forgo treatment despite the fact that receiving standard of care treatment leads to a higher OS.

Nut Consumption Inversely Associated With Lung Cancer Risk

Nut Consumption Inversely Associated With Lung Cancer Risk

A higher consumption of nuts was associated with a lower overall risk for developing lung cancer irrespective of smoking status.

Many VHA Patients Eligible for Lung Cancer Screening

Many VHA Patients Eligible for Lung Cancer Screening

Second study shows increase in lung cancer screening from 1.3 to 2.1 percent from 2010 to 2015

Addition of Bevacizumab to Chemo Improves PFS in Extensive SCLC

Addition of Bevacizumab to Chemo Improves PFS in Extensive SCLC

The addition of bevacizumab to first-line treatment with cisplatin plus etoposide improved PFS, but not OS, with an acceptable toxicity profile in patients with extensive-disease SCLC.

Use of Upfront TKIs Linked to Inferior OS in EGFR+ NSCLC With Brain Metastases

Use of Upfront TKIs Linked to Inferior OS in EGFR+ NSCLC With Brain Metastases

Treatment options for brain metastases in patients with EGFR-mutant NSCLC include SRS, WBRT, and EGFR TKIs. In this study, researchers sought to determine the optimal treatment approach of those who develop brain metastases and have not received EFGR TKIs.

First-line Ceritinib Improves PFS vs Chemo in Advanced ALK-rearranged NSCLC

First-line Ceritinib Improves PFS vs Chemo in Advanced ALK-rearranged NSCLC

Ceritinib is a kinase inhibitor indicated for the treatment of patients with ALK-positive metastatic NSCLC who have progressed on or are intolerant to crizotinib; in this study, researchers determined the efficacy of ceritinib in patients with untreated ALK-rearranged NSCLC.

Many Advanced NSCLC Patients Not Getting Helpful Treatment

Many Advanced NSCLC Patients Not Getting Helpful Treatment

Study found 21 percent of those with late-stage non-small cell lung cancer went without therapy, even though it could boost survival.

Tobacco Counseling for Youth, Adults Reduces Smoking Prevalence

Tobacco Counseling for Youth, Adults Reduces Smoking Prevalence

Annual counseling could reduce prevalence and prevent many smoking-attributable fatalities.

No Differences in Lung Cancer Mutations Between White, Black Patients

No Differences in Lung Cancer Mutations Between White, Black Patients

Analyses of lung tumor specimens were used to determine whether mutational profiles of lung cancers differ between black and white patients. Such differences could explain differences in prognosis and lead to reductions in outcomes disparities.

Lung Cancer Navigator App Aims to Help Patients Understand Disease

Lung Cancer Navigator App Aims to Help Patients Understand Disease

Lung Cancer Navigator, a mobile, customizable app from LUNGEVITY, helps patients with lung cancer better understand their disease, manage medications, track symptoms, and access support.

Considerable Shifts in NSCLC Treatment With Modest Gains in Survival

Considerable Shifts in NSCLC Treatment With Modest Gains in Survival

Investigators report on trends in treatment of advanced-stage NSCLC from 2000 to 2011, including impact on survival and total Medicare spending.

Delayed Adjuvant Chemotherapy Not Associated With Survival in NSCLC

Delayed Adjuvant Chemotherapy Not Associated With Survival in NSCLC

Study evaluated differences in survival with respect to the time interval between tumor resection and initiation of postoperative chemotherapy in patients with NSCLC.

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