Liver Cancer

Daily Aspirin Reduced Risk of HBV-Related Hepatocellular Carcinoma

Daily Aspirin Reduced Risk of HBV-Related Hepatocellular Carcinoma

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Study presented at the AASLD The Liver Meeting 2017 demonstrated the effect of regular aspirin use on risk of hepatocellular carcinoma in patients with chronic HBV.

Reduced-Dose Sorafenib Effective and Economical in Hepatocellular Carcinoma

Reduced-Dose Sorafenib Effective and Economical in Hepatocellular Carcinoma

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Reducing the initial dose of sorafenib was shown to have some benefits — such as reduced pill burden, lower costs, and decreased AE-related discontinuation rates — and OS was noninferior compared with the standard dose in patients with hepatocellular carcinoma.

Palliative Care Use Up for End-Stage Liver Disease

Palliative Care Use Up for End-Stage Liver Disease

Hispanic race and insurance coverage associated with lower referral to palliative care, data indicates.

Increases in Liver Cancer Incidence Influenced by Higher Rates of Comorbidities

Increases in Liver Cancer Incidence Influenced by Higher Rates of Comorbidities

A new report from ACS describes trends in liver cancer and the factors influencing the ongoing increase in incidence, particularly higher rates of HCV infection, obesity, and type 2 diabetes.

Liver Cancer the Fastest-Growing Cause of Cancer Deaths in United States

Liver Cancer the Fastest-Growing Cause of Cancer Deaths in United States

Liver cancer mortality has increased at a faster pace than other cancers in the United States, but substantial disparities exists in mortality rates for race/ethnicity and state of residence.

Durable Response Seen in Advanced HCC With Nivolumab

Durable Response Seen in Advanced HCC With Nivolumab

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New data presented at the International Liver Congress 2017 suggest that nivolumab may produce long-term benefits in sorafenib-experienced patients with advanced HCC.

Research Shows iPS-ML/IFN-β Migrates to, Penetrate Liver Cancer Tumors

Research Shows iPS-ML/IFN-β Migrates to, Penetrate Liver Cancer Tumors

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Decreased liver tumor growth and improved survival in a mouse model were noted after injecting iPS-ML/IFN-β.

A Single Institution Report of 19 Hepatocellular Carcinoma Patients With Bile Duct Tumor Thrombus

A Single Institution Report of 19 Hepatocellular Carcinoma Patients With Bile Duct Tumor Thrombus

[Journal of Hepatocellular Carcinoma] This research examines the outcomes of HCC patients with BDTT in a single institution.

Serum Liver Enzymes Serve as Prognostic Factors in Patients With Intrahepatic Cholangiocarcinoma

Serum Liver Enzymes Serve as Prognostic Factors in Patients With Intrahepatic Cholangiocarcinoma

This study examines the influences of liver enzymes on the overall survival in a number of patients with intrahepatic cholangiocarcinoma (ICC).

Cabozantinib Active in Hepatocellular Carcinoma

Cabozantinib Active in Hepatocellular Carcinoma

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Treatment with cabozantinib was active and associated with manageable toxicities in patients with hepatocellular carcinoma.

Pediatric Hepatocellular Carcinoma: Challenges and Solutions

Pediatric Hepatocellular Carcinoma: Challenges and Solutions

[Journal of Hepatocellular Carcinoma] This research examines the medical challenges presented by pediatric hepatocellular carcinoma (HCC).

Profile of Tivantinib and its Potential in the Treatment of Hepatocellular Carcinoma: The Evidence to Date

Profile of Tivantinib and its Potential in the Treatment of Hepatocellular Carcinoma: The Evidence to Date

[Journal of Hepatocellular Carcinoma] This research examines tivantinib and its therapeutic profile in the management of hepatocellular carcinoma.

Prognostic role of pretreatment serum albumin in renal cell carcinoma: a systematic review and meta-analysis

Prognostic role of pretreatment serum albumin in renal cell carcinoma: a systematic review and meta-analysis

[OncoTargets and Therapy] This research examines the prognostic value of pretreatment serum albumin in RCC patients.

Hepatocellular Carcinoma: A Review

Hepatocellular Carcinoma: A Review

[Journal of Hepatocellular Carcinoma] This research examines the screening modalities, diagnosis, staging, and treatment of hepatocellular carcinoma (HCC), the most common primary liver malignancy.

Role of Regorafenib as Second-line Therapy and Landscape of Investigational Treatment Options in Advanced Hepatocellular Carcinoma

Role of Regorafenib as Second-line Therapy and Landscape of Investigational Treatment Options in Advanced Hepatocellular Carcinoma

[Journal of Hepatocellular Carcinoma] This review examines the multikinase inhibitors sorafenib and regorafenib, inhibitors of the MET pathway, and immunotherapeutics for the treatment of advanced hepatocellular carcinoma.

Study Assesses Efficacy of Ramucirumab in HCC by Child-Pugh Score

Study Assesses Efficacy of Ramucirumab in HCC by Child-Pugh Score

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In patients with advanced HCC and a baseline αFP level of 400 ng/mL or more, a survival benefit with second-line ramucirumab therapy was observed for those with Child-Pugh scores of 5 and 6.

Second-Line Regorafenib Improves Overall Survival in Refractory Liver Cancer

Second-Line Regorafenib Improves Overall Survival in Refractory Liver Cancer

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The multikinase inhibitor regorafenib significantly improved overall survival rates compared to placebo in patients with hepatocellular carcinoma, according to data from the phase 3 RESORCE trial.

Comparative Efficacy and Safety of Axitinib Versus Sorafenib in Metastatic Renal Cell Carcinoma: A Systematic Review and Meta-analysis

Comparative Efficacy and Safety of Axitinib Versus Sorafenib in Metastatic Renal Cell Carcinoma: A Systematic Review and Meta-analysis

[Oncotargets and Therapy] This research evaluates the comparative efficacy and safety of axitinib and sorafenib for the treatment of metastatic renal cell carcinoma.

Premedication With Antiemetic Improves Length of Stay and Readmissions for a Liver Cancer Procedure

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Including an antiemetic in the preprocedure medications for patients with liver cancer undergoing drug eluting bead chemoembolization (DEB TACE) can shorten hospital stays and reduce the chance for readmission due to complications.

Adding Doxorubicin to Sorafenib Does Not Improve Overall Survival in Hepatocellular Carcinoma

Adding Doxorubicin to Sorafenib Does Not Improve Overall Survival in Hepatocellular Carcinoma

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In patients with advanced hepatocellular carcinoma (HCC), adding doxorubicin to sorafenib did not improve overall survival or progression-free survival and resulted in higher toxicity compared to sorafenib alone, results from a phase 3 study presented at the ASCO 2016 Annual Meeting have shown.

Survival for Patients With Liver Cancer Differs by Race

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A study of nearly 1000 patients with HCC found that black patients with the disease had a 33% greater risk of death compared with non-Hispanic whites.

Oncology Nurses Ideal for Educating Patients on Portal Vein Thrombosis

Oncology Nurses Ideal for Educating Patients on Portal Vein Thrombosis

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Oncology nurses are in an ideal position to educate patients with gastrointestinal malignancies and PVT about risk factors, clinical presentation, complications, and treatment options to prevent further extension of the clot.

Novel Delivery Method Repurposes Existing Drug to Treat Liver Cancer

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An interdisciplinary collaboration between prominent academic and industry investigators discovered a novel method for repositioning an FDA-approved anticancer compound so it can specifically target liver cancer tumors.

Blood Sample Offers a New Way of Detecting Cancer

Blood Sample Offers a New Way of Detecting Cancer

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RNA test of blood platelets can detect, classify, and pinpoint the location of cancer by analyzing a sample equivalent to 1 drop of blood. Using this new method, researchers were able to identify cancer with 96% accuracy.

New Approach to Postsurgical Care Reduces Patient Recovery Time After Liver Resection

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Patients undergoing oncologic liver surgeries who participated in an enhanced recovery program returned sooner to their normal life function and to adjuvant cancer therapies than patients who were treated with a traditional approach to perioperative care.

Probiotics Lower Rate of Infection Following Liver Transplant

Probiotics Lower Rate of Infection Following Liver Transplant

Results of a meta-analysis shows reduction in rate of infection and shorter length of hospital stay with receipt of prebiotics and probiotics before surgery.

Higher risk of liver cancer seen in women with intrahepatic cholestasis of pregnancy

Higher risk of liver cancer seen in women with intrahepatic cholestasis of pregnancy

Women with intrahepatic cholestasis of pregnancy (ICP) are at increased risk of hepatobiliary cancer.

Cancer risk linked to incidence of intrahepatic cholestasis of pregnancy

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The risk of hepatobiliary cancer and immune-mediated and cardiovascular diseases later in life is increased in women with intrahepatic cholestasis of pregnancy (ICP) than in women without this condition.

Tenofovir may reduce risk of liver cancer in patients with HBV infection

Tenofovir may reduce risk of liver cancer in patients with HBV infection

Long-term therapy with tenofovir was associated with a decreased incidence of HCC among patients with chronic HBV infection without cirrhosis.

Livers donated after cardiac death safe for use by liver cancer patients

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Livers donated to cancer patients by individuals that died of cardiac death do not yield outcomes worse than those donated by people dying from brain death.

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