By combining a zebrafish model of liver cancer with data from human tumors, researchers hope to identify potential genes of interest that can be targeted for new treatments for hepatocellular carcinoma.
A team of researchers has identified a novel mutation in the hepatitis B virus (HBV) in Korea that appears only in men and could help explain why HBV-infected men are roughly five times more likely than HBV-infected women to develop liver cancer.
Researchers have isolated and characterized the progenitor cells that give rise to malignant hepatocellular carcinoma tumors long before the actual tumors can be detected.
Meta-analysis pooled the results of 16 studies that examined the association between coffee consumption and liver cancer and coffee consumption was associated with a significantly lower risk of HCC.
This fact sheet reviews primary and secondary liver cancer types, symptoms, screening, and treatment.
New light was shed on the use of TACE and SIRT in the treatment of hepatocellular carcinoma (HCC) by data from clinical trials presented at the International Liver Congress 2013 in Amsterdam, the Netherlands.
New data from two clinical trials presented at the International Liver Congress 2013 demonstrated substantial improvements in the detection of both HCC and cholangiocarcinoma using diagnostic urine tests.
Combining cetuximab (Erbitux) with standard therapy improved the resectability of previously inoperable liver metastases of colorectal cancer.
Monitoring the hepatic function of unresectable liver cancer patients provides vital information that could guide more customized treatment plans and reduce risks of liver injury.
Plant-based drugs primarily used in the treatment of heart failure and arrhythmias have now been found to exert anticancer effects.
Vitamin E from diet or supplements may reduce the risk of developing liver cancer.
Overall US cancer death rates have continued to decline since the early 1990s, but excess weight and lack of sufficient activity contribute to the increased incidence of many cancers.
Pioglitazone, rosiglitazone linked to lower liver cancer risk; rosiglitazone tied to lower CRC risk.
Sorafenib, sunitinib, and pazopanib have been found to carry a heightened risk of fatal complications, but the incidence remains low overall.
Mutations found in about a quarter of cholangiocarcinomas of intrahepatic origin.
Cancer incidence rates in men declined by 0.6% per year and remained stable in women and cancer mortality fell by 1.8% per year for men and by 1.6% per year for women between 2004 and 2008.
Progression-free survival improved in patients with advanced neuroendocrine tumors when everolimus rather than placebo was used in combination with octreotide long-acting repeatable.
Metformin, a widely used agent in the treatment of type 2 diabetes, stopped a number of natural and man-made chemicals from stimulating the growth of breast cancer cells.
Compared with the general population, recipients of a kidney, liver, heart, or lung transplant have twice as great a risk for diverse infection-related and unrelated cancers.
Applying caffeine directly to the skin may eventually prove to help prevent sunlight-induced skin cancer, suggest the findings from a recent mouse study.
A multicenter study conducted across Europe indicates that the liver-directed therapy, radioembolization, can be used to achieve survival in persons with hepatocellular carcinoma—including those with advanced disease and few treatment options.
An analysis published online by CMAJ charges that current guidelines for alcohol consumption are inadequate for cancer prevention and that new international guidelines are needed.
Presentations on emerging standards of care in radiotherapy from the Future of Radiation Medicine 2011 symposium are reviewed.
A cyclooxygenase-2 (COX-2) selective nonsteroidal anti-inflammatory drug (NSAID) usually prescribed to relieve arthritis pain appears to be an effective treatment for liver cancer.
People with metabolic syndrome may have heightened risks of developing hepatocellular carcinoma and intrahepatic cholangiocarcinoma, the two most common types of liver cancer.
Higher doses of yttrium-90 (Y-90) than previously used in intra-arterial radioembolization to treat persons with liver tumors provide results when chemotherapies have failed.
Overall, cancer incidence rates fell approximately 1% annually and overall death rates decreased by an average of 1.6% annually between 2003 and 2007.
The limited therapeutic options for hepatocellular carcinoma may have just broadened with the discovery of a new molecular target for the disease.
The presence of high levels of a particular protein in tumors drives metastasis, providing a valuable biomarker for predicting the spread of cancer.
These interventional oncology strategies are a new and promising group of minimally invasive alternatives to surgical resection of tumors.
Interventional oncology strategies are a new and promising group of minimally invasive alternatives to surgical resection of tumors.
Patients with liver cancer may benefit from treatment beyond transplantation criteria, according to a study published in Liver Transplantation (2010 Aug;16(8):925-9).
Antiviral therapy can prevent recurrence of hepatocellular carcinoma (HCC) and extend the lives of patients with chronic hepatitis B (CHB), according to a study conducted by researchers from the Division of Gastroenterology and Hepatology at Thomas Jefferson University.
Researchers have identified genetic signatures that may help predict liver cancer recurrence, according to a study presented at the Annual Meeting of the European Association for the Study of the Liver.
Researchers have identified a link between obesity and an increased risk of developing cancer, according to a study published in the journal Cell (2010;140:197-208).
Drinking a pint of beer, a large glass of wine or a couple of measures of spirits a day increases the risk of liver and bowel cancer by a fifth, according to researchers.
A 35-year-old woman presents with a one-day history of lower-right abdominal pain, setting the stage for chemotherapy for metastatic colorectal cancer
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