Generic Name and Formulations:
Chlordiazepoxide HCl 5mg, 10mg, 25mg; caps.
Valeant Pharmaceuticals, Inc
Indications for LIBRIUM:
Individualize. Mild-to-moderate: 5–10mg 3–4 times daily. Severe: 20–25mg 3–4 times daily. Elderly or debilitated: 5mg 2–4 times daily.
<6yrs: not recommended. ≥6yrs: 5mg 2–4 times daily. May increase to 10mg 2–3 times daily.
Risks from concomitant use with opioids; see Interactions. Therapy for >4 months. Suicidal tendencies. Depression. Psychosis. Porphyria. Seizure disorder. Monitor blood counts and liver function. Reevaluate periodically. Abuse potential (monitor). Drug or alcohol abuse. Avoid abrupt cessation. Change dose gradually. Renal or hepatic impairment. Elderly. Debilitated. Pregnancy (during the 1st trimester), nursing mothers: not recommended.
Increased sedation, respiratory depression, coma, and death with concomitant opioids; reserve use in those for whom alternative treatment options are inadequate; if needed, limit dosages/durations to minimum and monitor. Potentiates CNS depression with alcohol, other CNS depressants. Variable effects with anticoagulants. Avoid other psychotropics.
Drowsiness, CNS depression, ataxia, confusion, paradoxical excitement, memory impairment, nausea, constipation, blood dyscrasias, jaundice, skin eruptions, edema, extrapyramidal effects.
- Neurotoxicity After CAR T-cell Therapy May Be Associated With Endothelial Activation
- Navigation Programs Most Effective in Increasing Follow-up Colonoscopy
- New Class of Clinical Trial Enhances Research on Cancer Care Delivery
- Specialized Interventions Reduce Aberrant Opioid Behaviors in Cancer Patients
- Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC
- Anticancer Properties of The Probiotic Kefir: A Review
- Navigating the Transition From Treatment to Breast Cancer Survivor
- Combining Radiation, Immunotherapy: An Emerging Challenge for Oncology Nursing
- Naldemedine Effective for Opioid-Induced Constipation in Cancer Pain
- Disruptions to Circadian Rhythm Linked to Prostate Cancer Surgery Regret
- Case Report of a KIT-mutated Melanoma Patient With an Excellent Response to Apatinib and Temozolomide Combination Therapy
- Novel Predictive Model More Effectively Identifies Risk for Lung Cancer
- Long-Term Eltrombopag Increases Platelet Counts, Decreases Bleeding in ITP
- Overall Survival Increase for Melanoma Brain Metastases
- Prophylactic Prochloperazine Ineffective for Opioid-induced Nausea/Vomiting in Cancer
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|