ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

LEVOPHED
CHF and arrhythmias
Hypotension
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

LEVOPHED Rx

Generic Name and Formulations:
Norepinephrine bitartrate 1mg/mL (equivalent of 1mg base of norepinephrine); soln for IV infusion after dilution; contains sulfites.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for LEVOPHED:

Adjunctive treatment in cardiac arrest and profound hypotension.

Adult:

Correct blood volume depletion before administration. Give by IV infusion after dilution (contains 4mcg of base/mL) into a large vein. Initially 2mL to 3mL (or 8–12mcg of base) per minute; adjust flow rate until adequate low normal BP (usually 80–100 mmHg systolic) and maintain tissue perfusion. Usual maintenance: 0.5mL to 1mL (or 2–4mcg of base) per minute. Withdraw gradually. Titrate dose based on response: see literature.

Children:

Not recommended.

Contraindications:

Hypotension due to blood volume deficits except as an emergency measure. Mesenteric or peripheral vascular thrombosis. Profound hypoxia or hypercabia. Concomitant cyclopropane and halothane anesthesia.

Warnings/Precautions:

Hypertension. Monitor BP every 2 minutes initially until desirable level is obtained, then every 5 minutes if administration is continued. Avoid extravasation. Asthma. Sulfite sensitivity. Elderly (avoid infusion into leg veins). Pregnancy (Cat. C). Nursing mothers.

Interactions:

See Contraindications. Risk of ventricular tachycardia or fibrillation with cyclopropane, halothane anesthesia. Caution with MAOIs, triptyline or imipramine antidepressants; may cause prolonged hypertension.

Pharmacological Class:

Sympathomimetic.

Adverse Reactions:

Ischemic injury, reflex bradycardia, arrhythmias, anxiety, transient headache, respiratory difficulties, extravasation necrosis, volume depletion (esp. long-term use).

How Supplied:

Ampuls (4mL)—10

Indications for LEVOPHED:

To restore blood pressure control in certain acute hypotensive states (eg, pheochromocytomectomy, sympathectomy, poliomyelitis, spinal anesthesia, MI, septicemia, blood transfusion, and drug reactions).

Adult:

Correct blood volume depletion before administration. Give by IV infusion after dilution (contains 4mcg of base/mL) into a large vein. Initially 2mL to 3mL (or 8–12mcg of base) per minute; adjust flow rate until adequate low normal BP (usually 80–100 mmHg systolic) and maintain tissue perfusion. Usual maintenance: 0.5mL to 1mL (or 2–4mcg of base) per minute. Withdraw gradually. Titrate dose based on response: see literature.

Children:

Not recommended.

Contraindications:

Hypotension due to blood volume deficits except as an emergency measure. Mesenteric or peripheral vascular thrombosis. Profound hypoxia or hypercabia. Concomitant cyclopropane and halothane anesthesia.

Warnings/Precautions:

Hypertension. Monitor BP every 2 minutes initially until desirable level is obtained, then every 5 minutes if administration is continued. Avoid extravasation. Asthma. Sulfite sensitivity. Elderly (avoid infusion into leg veins). Pregnancy (Cat. C). Nursing mothers.

Interactions:

See Contraindications. Risk of ventricular tachycardia or fibrillation with cyclopropane, halothane anesthesia. Caution with MAOIs, triptyline or imipramine antidepressants; may cause prolonged hypertension.

Pharmacological Class:

Sympathomimetic.

Adverse Reactions:

Ischemic injury, reflex bradycardia, arrhythmias, anxiety, transient headache, respiratory difficulties, extravasation necrosis, volume depletion (esp. long-term use).

How Supplied:

Ampuls (4mL)—10

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs