Childhood cancer survivors are at heightened risk of a wide range of autoimmune diseases. Diabetes and Addison's disease make up almost half of the excess cases, according to the findings.
Biologic Age Need Not be a Limiting Factor for Stem Cell Transplants in Patients with Acute Myeloid Leukemia (AML)November 25, 2015
More than 40% of older patients with AML can remain in long-term cancer remission through a modified, less aggressive approach to donor stem cell transplantation, according to the results of a phase 2 study.
Researchers announced a breakthrough advance in a world-first international clinical trial of a new drug to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma that is refractory or resistant to current chemotherapies.
The Association Between XRCC1 Arg399Gln Polymorphism and Risk of Leukemia in Different Populations: A Meta-Analysis of Case-Control StudiesNovember 20, 2015
This research examines the association between XRCC1 SNPs and leukemia.
Inherited Gene Variation Linked to an Increased Risk of Pediatric Acute Lymphoblastic Leukemia (ALL)November 11, 2015
Researchers studying two generations of a family affected by pediatric ALL identified an inherited variation in the ETV6 gene that is associated with an increased risk of developing the disease.
Bosutinib continues to demonstrate durable long-term efficacy and manageable toxicity in patients with chronic myeloid leukemia (CML).
Many types of leukemia are caused by loss of enzymes such as Pten, or conversely, the over-activation of enzymes that normally enhance cell proliferation, such as Shp2. But researchers have now found that a lack of both Pten and Shp2 results in an inability produce and sustain enough red blood cells.
A molecule isolated from sea sponges and later synthesized can halt the growth of cancerous cells, opening the door to a new treatment for leukemia.
Bone marrow transplantation is a life-saving treatment for many people with blood cancers such as leukemia and lymphomas.
Patient-reported outcomes have the potential to improve prognostication in patients undergoing hematopoietic stem cell transplantation (HSCT).
A study of the risk of acute leukemia that considered all 2,760 cases of leukemia in children younger than 15 years in metropolitan France between 2002 and 2007 found that the incidence of myeloblastic leukemia was 30% higher among children who lived within 150 m of heavily used roads.
Prophylactic therapy with granulocyte-macrophage colony-stimulating factor (GM-CSF) may decrease invasive fungal disease (IFD).
Eight of 14 patients in the first clinical trial of personalized cellular therapy for chronic lymphocytic leukemia (CLL) responded to the therapy, with some complete remissions continuing beyond 4.5 years.
Engineering CAR T cells to lower their affinity for the protein EGFR made the cells preferentially recognize and eliminate tumor cells, which have high amounts of EGFR, sparing normal cells, which have lower amounts of the protein, according to a preclinical study.
Increased risk of childhood leukemia and lymphoma has been observed with indoor insecticide exposure.
A link between malaria and Burkitt's lymphoma was first described more than 50 years ago, but how a parasitic infection could turn immune cells cancerous has remained a mystery. Now, researchers have demonstrated in mice that B cell DNA becomes vulnerable to cancer-causing mutations.
A new tool predicts what genetics are truly driving the cancer in any population of cells and helps the user choose the best kinase inhibitor to address the issue.
Intravenous busulfan plus cyclophosphamide may be a valid and efficient alternative for patients with refractory acute myeloid leukemia.
Among long-term survivors of hematopoetic cell transplantation (HCT), patient-reported resilience is independently associated with outcomes.
Amgen's Blincyto costs about 178,000 for a standard course of treatment.
You research has shed light on the process by which mutated genes in leukemia reprogram blood stem cells and send them spiraling out of control.
Greatly improved outcomes have been observed in using stem cell transplantation to treat patients with juvenile myelomonocytic leukemia (JMML), a rare form of blood cancer.
Disparities in treatment outcomes for younger patients with acute promyelocytic leukemia (APL) exist.
Tyrosine kinase inhibitors (TKIs) seem safe in patients with chronic myeloid leukemia (CML) in chronic-phase and chronic kidney disease.
New compound that locks a disease-related protein into an inactive position stifled the growth of an aggressive form of leukemia.
Scientists have discovered that a common drug given to arthritis sufferers could also help to treat patients with blood cancers.
A recently developed drug holds great promise for some children with acute lymphoblastic leukemia (ALL).
An experimental new treatment approach could buy patients with a rare and dangerous leukemia type the time to obtain a stem cell transplant.
Can molecules derived from avocados be used as a tool to combat leukemia?
Majority of existing drugs for hematologic cancers are priced too high to be considered cost-effective in the United States.
- Existing Drug May Limit Recurrence and Metastasis of Glioblastoma Multiforme
- New Blood Test Improves Screening for Prostate Cancer
- Blood Sample Offers a New Way of Detecting Cancer
- Nanoliposomal Irinotecan Extends Survival in Metastatic Pancreatic Cancer
- Timing Matters for Pegfilgrastim Administration
- Hospitals Should Enact Bereavement Programs, Researchers Urge
- Breastfeeding Associated With A Reduced Risk of Aggressive Breast Cancer
- Gut Bacteria Can Dramatically Amplify Cancer Immunotherapy
- Physical Activity Communications Should be Part of Oncology Care Clinic Visits With Patients
- Communication Practices of Many US Physicians May Be Discouraging HPV Vaccination
- ASH 2015 Placeholder
- Prescription Coverage Impacts Treatment Adherence in Breast Cancer, Even for Low-cost Drugs
- Late-onset Remission Seen in Patients With Lymphoma Treated with Immunomodulatory Drugs
- Impact of Early Palliative Care Varies Depending on Patient Age, Gender
- Weight Gain May Follow Head and Neck Cancer Operations
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