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KEFLEX
Bacterial infections
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Drug Name:

KEFLEX Rx

Generic Name and Formulations:
Cephalexin 250mg, 500mg, 750mg; caps.

Company:
Shionogi, Inc.

Therapeutic Use:

Indications for KEFLEX:

Susceptible infections including otitis media, skin and skin structure, bone, respiratory or genitourinary tract.

Adult:

1–4g/day in divided doses. Usual dose: 250mg every 6hrs. Strep pharyngitis, skin and skin structure, and uncomplicated cystitis (>15yrs of age): 500mg every 12hrs. Treat cystitis for 7–14 days. Max 4g/day.

Children:

25–50mg/kg per day in divided doses; max 100mg/kg per day. Otitis media: 75–100mg/kg per day in 4 divided doses. Strep pharyngitis (>1yr of age) or skin and skin structure: may give in 2 divided doses every 12hrs.

Warnings/Precautions:

Penicillin or other allergy. Severe renal dysfunction. GI disease (esp. colitis). Discontinue if colitis occurs and treat. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Potentiates metformin (monitor and adjust metformin dose). Potentiated by probenecid. May cause false (+) Coomb's test or glucose test with Clinitest or Benedict's or Fehling's soln.

Pharmacological Class:

Cephalosporin.

Adverse Reactions:

Diarrhea, other GI disturbances, dizziness, fatigue, headache, hypersensitivity reactions, itch; rare: blood dyscrasias, elevated liver enzymes.

How Supplied:

Caps 250mg, 500mg—20, 100; 750mg—50

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