ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

KAYEXALATE
Poisoning/overdose
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

KAYEXALATE Rx

Generic Name and Formulations:
Sodium polystyrene sulfonate; pwd; sodium content 4.1mEq/g.

Company:
Concordia Pharmaceuticals Inc.

Therapeutic Use:

Indications for KAYEXALATE:

Hyperkalemia.

Limitations Of use:

Not for treating life-threatening hyperkalemia due to its delayed onset of action.

Adult:

See full labeling. Oral: give in an upright position; 15g as a suspension 1–4 times daily. Rectal enema: 30–50g in 100mL every 6hrs.

Children:

See full labeling. 1g per 1mEq of potassium as basis of calculation may be used.

Contraindications:

Obstructive bowel disease. Neonates with reduced gut motility.

Warnings/Precautions:

Avoid in patients at risk for constipation/impaction (eg, history of impaction, chronic constipation, inflammatory bowel disease, ischemic colitis, vascular intestinal atherosclerosis, previous bowel resection, bowel obstruction); discontinue if constipation develops. Post-surgery: avoid if have not had a bowel movement. CHF, hypertension, edema: monitor for fluid overload. Risk of aspiration. Monitor electrolytes (eg, potassium, calcium, magnesium). Neonates: do not give by oral route. Infants.

Interactions:

Increased risk of intestinal necrosis with concomitant sorbitol; not recommended. Separate dosing by ≥3hrs before or ≥3hrs after other oral drugs (6hrs in patients with gastroparesis). Increased risk of systemic alkalosis with nonadsorbable cation-donating antacids and laxatives. Reduces absorption of thyroxine, lithium.

Pharmacological Class:

Cation exchange resin.

Adverse Reactions:

Anorexia, constipation, diarrhea, fecal impaction, GI concretions (bezoars), ischemic colitis, nausea, vomiting; intestinal necrosis, electrolyte disturbances.

How Supplied:

Jar (453g)—1

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs