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INDERAL LA
Angina
Hypertension
Migraine and headache
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Drug Name:

INDERAL LA Rx

Generic Name and Formulations:
Propranolol HCl 60mg, 80mg, 120mg, 160mg; sust-rel caps.

Company:
Ani Pharmaceuticals

Therapeutic Use:

Indications for INDERAL LA:

Long-term management of angina. Hypertrophic subaortic stenosis.

Adult:

Angina: Initially 80mg once daily. May increase at 3–7 day intervals; max 320mg daily. Stenosis: 80–160mg once daily.

Children:

Not recommended.

Contraindications:

Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.

Warnings/Precautions:

CHF. Wolff-Parkinson-White syndrome. Renal or hepatic dysfunction. Bronchospastic disease, COPD. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Potentiated by alcohol, CNS depressants, other antihypertensives, antithyroid drugs, haloperidol, chlorpromazine, cimetidine. Bradycardia with catecholamine-depleting drugs. Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. May increase cardiac effects of calcium channel blockers, digitalis, lidocaine. Potentiates theophylline, antipyrine, lidocaine. May block epinephrine. May interfere with glaucoma screening tests.

See Also:

INDERAL

Pharmacological Class:

Beta-blocker.

Adverse Reactions:

Heart failure, hypotension, bronchospasm, bradycardia, heart block, fatigue, dizziness, depression, GI upset, skin reactions (eg, rash, Stevens-Johnson syndrome, urticaria), pharyngitis, agranulocytosis.

How Supplied:

Tabs 60mg—100; 10mg, 20mg, 40mg, 80mg—100, 5000; LA—100

Indications for INDERAL LA:

Hypertension. Adjunct in pheochromocytoma.

Adult:

Initially 80mg daily. Usual maintenance: 120–160mg daily; max 640mg daily.

Children:

Not recommended.

Contraindications:

Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.

Warnings/Precautions:

CHF. Wolff-Parkinson-White syndrome. Renal or hepatic dysfunction. Bronchospastic disease, COPD. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Potentiated by alcohol, CNS depressants, other antihypertensives, antithyroid drugs, haloperidol, chlorpromazine, cimetidine. Bradycardia with catecholamine-depleting drugs. Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. May increase cardiac effects of calcium channel blockers, digitalis, lidocaine. Potentiates theophylline, antipyrine, lidocaine. May block epinephrine. May interfere with glaucoma screening tests.

See Also:

INDERAL

Pharmacological Class:

Noncardioselective beta-blocker.

Adverse Reactions:

Heart failure, hypotension, bronchospasm, bradycardia, heart block, fatigue, dizziness, depression, GI upset, skin reactions (eg, rash, Stevens-Johnson syndrome, urticaria), pharyngitis, agranulocytosis.

How Supplied:

Tabs 60mg—100; 10mg, 20mg, 40mg, 80mg—100, 5000; LA—100

Indications for INDERAL LA:

Migraine prophylaxis.

Adult:

Initially 80mg daily. Usual range: 160–240mg daily. Discontinue if poor result after 4–6 weeks.

Children:

Not recommended.

Contraindications:

Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.

Warnings/Precautions:

CHF. Wolff-Parkinson-White syndrome. Renal or hepatic dysfunction. Bronchospastic disease, COPD. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Potentiated by alcohol, CNS depressants, other antihypertensives, antithyroid drugs, haloperidol, chlorpromazine, cimetidine. Bradycardia with catecholamine-depleting drugs. Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. May increase cardiac effects of calcium channel blockers, digitalis, lidocaine. Potentiates theophylline, antipyrine, lidocaine. May block epinephrine. May interfere with glaucoma screening tests.

See Also:

INDERAL

Pharmacological Class:

Beta-blocker.

Adverse Reactions:

Heart failure, hypotension, bronchospasm, bradycardia, heart block, fatigue, dizziness, depression, GI upset, skin reactions (eg, rash, Stevens-Johnson syndrome, urticaria), pharyngitis, agranulocytosis.

How Supplied:

Tabs 60mg—100; 10mg, 20mg, 40mg, 80mg—100, 5000; LA—100

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