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Indapamide
Edema
Hypertension
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Drug Name:

Indapamide Rx

Generic Name and Formulations:
Indapamide 1.25mg, 2.5mg; tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Indapamide:

Edema.

Adult:

Initially 2.5mg once daily in the AM. After 1wk, may increase to 5mg daily.

Children:

Not recommended.

Contraindications:

Anuria. Sulfonamide allergy.

Warnings/Precautions:

Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, uric acid, glucose, and renal function. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Digitalis, lithium toxicity. Adjust antidiabetic medications. NSAIDs may cause renal failure. ACTH, corticosteroids increase hypokalemia risk. May potentiate other antihypertensives. May block epinephrine. May interfere with parathyroid tests.

Pharmacological Class:

Diuretic (indoline).

Adverse Reactions:

Electrolyte disorders (esp. hypokalemia, hyponatremia), hyperglycemia, hyperuricemia, gout, arrhythmias, headache, nervousness, blurred vision, muscle cramps, dizziness, fatigue, orthostatic hypotension, cough, GI disturbances.

Note:

Formerly known under the brand name Lozol.

How Supplied:

Contact supplier.

Indications for Indapamide:

Hypertension.

Adult:

Initially 1.25mg once daily in the AM. May adjust at 4 week intervals to 2.5mg then 5mg once daily.

Children:

Not recommended.

Contraindications:

Anuria. Sulfonamide allergy.

Warnings/Precautions:

Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, uric acid, glucose, and renal function. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Digitalis, lithium toxicity. Adjust antidiabetic medications. NSAIDs may cause renal failure. ACTH, corticosteroids increase hypokalemia risk. May potentiate other antihypertensives. May block epinephrine. May interfere with parathyroid tests.

Pharmacological Class:

Diuretic (indoline).

Adverse Reactions:

Electrolyte disorders (esp. hypokalemia, hyponatremia), hyperglycemia, hyperuricemia, gout, arrhythmias, headache, nervousness, blurred vision, muscle cramps, dizziness, fatigue, orthostatic hypotension, cough, GI disturbances.

Note:

Formerly known under the brand name Lozol.

How Supplied:

Contact supplier.

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