Imaging

Squamous Cell carcinoma of the skin

Preliminary Diagnosis: Squamous cell carcinoma of the skin

I. What imaging technique is first-line for this diagnosis

  • CT with contrast

II. Describe the advantages and disadvantages of this technique for diagnosis of squamous cell carcinoma of the skin.

Advantages

  • Relatively quick and inexpensive imaging modality.

  • Offers exquisite detail of the surrounding osseous structures.

Disadvantages

  • Exposes patients to ionizing radiation.

  • May be difficult to interpret in postoperative patients as fat planes and enhancement is distorted.

  • Less sensitive in detecting subtle primary tumor or metastatic lymph nodes compared with other imaging modalities

III. What are the contraindications for the first-line imaging technique?

  • May be contraindicated in pregnant patients.

  • Relative contraindication to contrast use in patients with renal failure

  • Relative contraindication to contrast use in patients with contrast allergy

IV. What alternative imaging techniques are available?

  • MRI

  • PET/CT imaging.

V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of squamous cell carcinoma of the skin.

MRI

Advantages

  • Does not expose the patient to ionizing radiation.

  • Highly sensitive and specific in detecting and detailing the extent of tumoral infiltration and any perineural infiltration.

Disadvantages

  • Less sensitive and less adept in detailing and detecting osseous involvement of neoplasm.

  • Expensive

  • Time-consuming

  • Requires significant patient cooperation to minimize motion artifact

PET/CT imaging

Advantages

  • Highly sensitive and specific in detecting focal areas suspicious for primary and metastatic tumor.

  • Highly sensitive and specific in detecting residual or recurrent neoplasm post biopsy.

  • Gold standard in staging tumor.

  • High negative predictive value and may help alter treatment.

Disadvantages

  • Exposure to ionizing radiation

VI. What are the contraindications for the alternative imaging techniques?

MRI

  • May be contraindicated in patients with non-MR compatible hardware.

PET/CT imaging

  • May be contraindicated in patients who are pregnant and/or breastfeeding.

You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs