Hematologic Cancer News and Features

Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT

Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT

Researchers sought to determine if NMA or reduced-intensity conditioning with busulfan improved severity/duration of oral mucositis compared with myeloablative conditioning in patients with hematologic cancer undergoing HCT.

FDA, EU Approvals Sought for Split Dose Regimen of Daratumumab for Multiple Myeloma

FDA, EU Approvals Sought for Split Dose Regimen of Daratumumab for Multiple Myeloma

The manufacturer of daratumumab, a CD38-directed antibody for the treatment of multiple myeloma, has submitted a sBLA and a type II variation to the US FDA and European Medicines Agency, respectively, for approval of a split dosing regimen.

8 Hours of Bedrest May Be Ideal After Intrathecal Chemotherapy in Hematologic Cancers

8 Hours of Bedrest May Be Ideal After Intrathecal Chemotherapy in Hematologic Cancers

In an open-label study, researchers sought to determine the optimal amount of bed rest after intrathecal chemotherapy for patients with hematologic cancers.

Long-Term Azithromycin May Increase Risk of Relapse of Blood Cancers After HSCT

Long-Term Azithromycin May Increase Risk of Relapse of Blood Cancers After HSCT

US FDA issues a recommendation on use of azithromycin in patients with hematologic malignancies who have undergone HSCT.

Effect of HSCT on HRQOL and Posttraumatic Stress in Young Adult Cancer Survivors

Effect of HSCT on HRQOL and Posttraumatic Stress in Young Adult Cancer Survivors

Study sought to determine the health-related QOL and posttraumatic stress symptoms in adolescent and young adult cancer survivors post-HSCT compared with their healthy peers.

Bleeding Disorder Treatments: von Willebrand Disease

Treatment options for von Willebrand Disease (VWD).

Qualitative Analysis of Myeloma Patients' Experience Following Hematopoietic Stem Cell Transplant

Qualitative Analysis of Myeloma Patients' Experience Following Hematopoietic Stem Cell Transplant

In this study, researchers investigated the effects of exercise on physical and psychological recovery after autoHSCT for multiple myeloma.

Isolated mild/moderate thrombocytopenia may not require intervention

1. In a review of children who presented to a specialist hematology clinic with isolated mild or moderate low platelet counts, though causes were variable, most required no interventions. 2. Pediatric patients with isolated mild or moderate thrombocytopenia may not need specialist referral to hematology in most circumstances. Evidence Rating Level: 2 (Good) Study Rundown: []

Navigating Patients with Hematologic Malignancies

Navigating Patients with Hematologic Malignancies

Patients with hematologic cancers often require a combination of inpatient and outpatient care. The oncology nurse navigator is an ideal care provider to help patients manage their care and transitions between care settings, according to a presentation at the 2018 ONA Navigation Summit.

Palliative Issues Inadequately Addressed Among Hospitalized Cancer Patients

Palliative Issues Inadequately Addressed Among Hospitalized Cancer Patients

Consultations for palliative care for hospitalized highly symptomatic patients with cancer is low regardless of curability or whether patient has hematologic or solid cancer, a study presented at 2018 ASCO has shown.

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