No evidence to support use of vitamin C supplementation in cancer
the ONA take:
According to a new study published in the journal The Oncologist, researchers have found that there is no high-quality evidence to support the use of ascorbate (vitamin C) supplementation to enhance efficacy or reduce toxicity of chemotherapy in patients with cancer.
For the systematic review, researchers from the Ottawa Hospital Cancer Centre Division of Medical Oncology in Ottawa, Ontario, Canada, sought to investigate whether supplemental ascorbate synergizes the anticancer effects of chemotherapy and reduces its toxicity.
Researchers identified 34 articles to be included in the study from Medline, EMBASE, and the Cochrane central register. Among those, there were five randomized controlled studies, 12 phase 1/2 studies, six observational trials, and 11 case reports.
The studies included a total of over 8,000 patients. Results showed no statistically significant improvements in overall survival or progression-free survival or reduced toxicity with supplemental ascorbate use compared with the control arm.
The authors note that high-quality placebo-controlled studies are needed to assess the effects of ascorbate on chemotherapy efficacy and toxicity in patients with cancer.
No high-quality evidence to support the use of ascorbate (vitamin C) supplementation to enhance cancer treatment.
- Immunotherapy May Benefit Some Patients with Papillary Thyroid Carcinoma
- New Study Questions Standard Dosage for Treating Metastatic Non-Small Cell Lung Cancer
- Superior Tolerability, Efficacy With Alectinib in Treatment-Naïve ALK-poistive NSCLC
- Adding Pertuzumab to Adjuvant Therapy Is Beneficial for Some Women with Early Breast Cancer
- Clinical Trials May Benefit Oncology Patients
- Survivorship Care Plans: Providing A Blueprint for Health Care After Cancer
- Cancer Recurrence Fear Reduced by Novel Psychological Intervention
- Multifaceted Role of the Nurse Navigator Includes Palliative, Supportive Care
- Patient Navigators Found to Boost Lung Cancer Screening Rates
- Breast Cancer Diagnosis and Nurse Navigation Survey
- Breast Cancer Overdiagnosis Also a Result of Screening Mammography Programs
- Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer
- Cancer Risk Not Increased by Childhood Exposure to Diagnostic Radiation
- Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes
- Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|