Study compares treatment risks for early esophageal cancer

the ONA take:

A new study, performed by researchers based at Northwestern Memorial Hospital in Chicago, Illinois, examined the risks associated with endoscopic resection for the treatment of localized, early-stage esophageal cancer. This study is the largest study to date to compare endoscopic and surgical treatments for localized, early-stage esophageal cancer.

Endoscopic esophageal resection, which has been growing in popularity, is a less invasive procedure in which an endoscope is guided through the gastrointestinal tract. In esophageal surgical resection, a portion of the patient’s esophagus is removed and the digestive tract is repaired using remaining, healthy sections.

Researchers found that traditional surgical resection had a 87.6 percent (five-year) survival rate whereas endoscopic resection was found to have a lower, 76 percent five-year (five-year) survival rate. The researchers noted that use of endoscopic esophageal resection increased from 19 to 53 percent over a six-year period from 2004 through 2010 for t1a cancers and rose from 6.6 to 20-9 percent during the same period for T1b cancers. (T1a tumors are less mature and closer to the surface than those in the T1b classification.) The found that roughly 20 percent of T1b cancers had spread to one or more lymph nodes, whereas only 5 percent of T1a had spread in such a fashion. 

Results of this study were published in the Journal of the National Cancer Institute.

Study compares treatment risks for early esophageal cancer
Study compares treatment risks for early esophageal cancer
CHICAGO – A new study, published in the July, 2014, issue of the Journal of the National Cancer Institute by Northwestern Medicine® researchers, sheds new light on the risks associated with the growing popularity of endoscopic resection in the treatment of localized, early-stage esophageal cancer. Researchers found that the more traditional surgical resection, while more invasive, provided significantly better outcomes with an 87.6 percent five-year survival rate for patients than endoscopic resection, which had a 76 percent five-year survival rate.
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