Smoking associated with increased mortality among colorectal cancer survivors

the ONA take:

According to a new study published online in the Journal of Clinical Oncology, American Cancer Society researchers have found that colorectal cancer survivors who smoke cigarettes are twice as likely to die compared with non-smoking survivors.

Existing evidence has shown that cigarette smoking is linked with increased all-cause mortality, increased colorectal cancer-specific mortality, and increased risk for developing colorectal cancer, but researchers sought to further investigate the association between smoking pre- and post-diagnosis and all-cause and colorectal cancer-specific mortality among survivors of colorectal cancer.

Researchers identified 2,548 patients with newly diagnosed invasive, non-metastatic colorectal cancer in the American Cancer Society's Cancer Prevention Study II. Of those, 1,074 died, including 453 due to colorectal cancer, during a mean follow-up duration of 7.5 years.

Results showed that patients who smoked pre-diagnosis were more than twice as likely to die from all causes and colorectal cancer. In addition, former smokers before diagnosis had a higher risk of dying from any cause, but not specifically colorectal cancer.

Researchers found that smoking post-diagnosis also doubled survivors' risk of all-cause mortality and colorectal cancer-specific mortality.

Smoking associated with increased mortality among colorectal cancer survivors
Colorectal cancer survivors who smoke cigarettes are twice as likely to die compared with non-smoking survivors.
Existing evidence links smoking with higher chances of being diagnosed with colorectal cancer, but its association with survival after colorectal cancer diagnosis is unclear.
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