Headlines

Rabbit virus improves bone marrow transplants and kills some cancer cells

Researchers have discovered that a rabbit virus can deliver a one-two punch, killing some kinds of cancer cells while eliminating a common and dangerous complication of bone marrow transplants.

Increasing percentages of patients undergoing breast-conserving therapy

The percentage of patients with early stage breast cancer undergoing breast-conserving therapy (BCT) increased from 54.3% in 1998 to 60.1% in 2011, according to a recent report. Notably, nonclinical factors including socioeconomic demographics, insurance, and the distance patients must travel to treatment facilities persist as key barriers to the treatment.

ALK1 protein may play a role in breast cancer metastasis

Breast cancer patients with high levels of the protein activin-like receptor kinase (ALK1) in the blood vessels of their tumors were more likely to develop metastatic disease, according to a new study. This makes inhibition of the ALK1 pathway a possible new target for the treatment of metastatic breast cancer.

Follow-up PET/CT more than 95% sensitive for non-Hodgkin lymphoma

BALTIMORE, MD—For more aggressive cases of non-Hodgkin lymphoma (NHL), posttreatment surveillance with molecular imaging could mean the early start of a new, life-saving treatment. This was presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2015 Annual Meeting.

Distinct triple-positive subtypes identified in breast cancer

CHICAGO, IL—Functional subtyping with a multigene classifier resulted in 1 in 5 tumors being reclassified compared with conventional immunohistochemistry/fluorescent in situ hybridization (IHC/FISH) analysis. This study was presented at the 2015 American Society for Clinical Oncology (ASCO) Annual Meeting.

Patients with pancreatic cancer report very high levels of needs

Patients with pancreatic cancer report very high levels of needs

People with pancreatic cancer or ampullary cancer reported very high levels of needs.

Consumption of sugary drinks associated with high death tolls

Consumption of sugary drinks associated with high death tolls

Consumption of sugary drinks could be responsible for an estimated 184,000 deaths worldwide every year.

Drug treatment may benefit only select group of patients with glioblastoma

Drug treatment may benefit only select group of patients with glioblastoma

Clinicians testing dasatinib, approved for several blood cancers, were hoping to find that it would slow the growth of glioblastomas.

10 percent urea cream superior to new ointment for hand-foot syndrome

10 percent urea cream superior to new ointment for hand-foot syndrome

10% urea cream is superior to a newly introduced ointment containing various antioxidants at preventing hand-foot syndrome.

Panobinostat combination demonstrates benefit in relapsed/refractory multiple myeloma

Panobinostat combination demonstrates benefit in relapsed/refractory multiple myeloma

Patients with relapsed or refractory myeloma experience the most benefit from panobinostat plus bortezomib and dexamethasone.

Conference Coverage

Follow-up PET/CT more than 95% sensitive for non-Hodgkin lymphoma

BALTIMORE, MD—For more aggressive cases of non-Hodgkin lymphoma (NHL), posttreatment surveillance with molecular imaging could mean the early start of a new, life-saving treatment. This was presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2015 Annual Meeting.

Distinct triple-positive subtypes identified in breast cancer

CHICAGO, IL—Functional subtyping with a multigene classifier resulted in 1 in 5 tumors being reclassified compared with conventional immunohistochemistry/fluorescent in situ hybridization (IHC/FISH) analysis. This study was presented at the 2015 American Society for Clinical Oncology (ASCO) Annual Meeting.

Removing more breast tissue reduces the need for a second cancer surgery

Expanded surgical margins during a partial mastectomy could be beneficial for patients, preventing further surgery.

Next-generation ALK-inhibitor brigatinib promising against NSCLC

Clinical trial results showed good performance employing the investigational drug brigatinib against ALK-positive non-small cell lung cancer (NSCLC).

Combining targeted drug with chemotherapy prolongs life for patients with B-cell lymphoma

The combination of ibrutinib and chemotherapy (bendamustine and rituximab [BR]) was found to reduce the risk of death by nearly 80% in patients with previously treated CLL or SLL.

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