Headlines

Chemotherapy-related Bone Loss in Children With ALL Occurs Earlier Than Previously Assumed

Chemotherapy-related Bone Loss in Children With ALL Occurs Earlier Than Previously Assumed

Significant bone loss in children receiving chemotherapy for acute lymphoblastic leukemia (ALL) occurs during the first month of treatment.

Data Analysis Shows 8-week Chemoradiotherapy-to-Surgery Timeline Achieves Optimal Tumor Response

Overall survival was best and resection of residual locally advanced rectal tumors most successful when surgery occurred at precisely 8 weeks, or 56 days, after completion of chemoradiotherapy.

Exercise During Neoadjuvant CRT Less Difficult Than Anticipated for Rectal Cancer

Exercise During Neoadjuvant CRT Less Difficult Than Anticipated for Rectal Cancer

Patients with rectal cancer reported aerobic exercise during neoadjuvant chemoradiotherapy to be more enjoyable and less difficult.

Early Onset of Everolimus Adverse Events Requires Thorough Patient Education

Early Onset of Everolimus Adverse Events Requires Thorough Patient Education

Almost half of patients with metastatic HR-positive breast cancer treated with everolimus and exemestane required a dose reduction.

Nanoparticle System Uses Light Waves to Target Release Site of Drug

Nanoparticles that release a drug only when exposed to near-infrared (NIR) light are a promising drug-delivery agent developed by Canadian researchers.

Delirium is Common in Older Patients Undergoing GI Surgery

Older patients undergoing gastrointestinal surgery often experience postoperative delirium. In an analysis of 11 studies, incidence of postoperative delirium ranged from 8.2% to 54.4%.

Nanoparticle Drug Delivery Aims to Control Pancreatic Tumor and Inhibit Escape Pathways

Use of a nanoparticle to deliver drugs may reduce tumors and suppress metastatic escape. These efforts offer a way to control drug release over space and time while reducing systemic drug exposure and the associated side effects.

Better Approaches to Patient Counseling of BRCA Gene Mutation Carriers Needed

Better Approaches to Patient Counseling of BRCA Gene Mutation Carriers Needed

An in-depth look at the issues associated with the care reveals a need to improve how clinicians can help these women sort through their options.

Meditation May Reduce Breast Biopsy Pain

Meditation May Reduce Breast Biopsy Pain

Listening to guided meditation significantly reduced biopsy pain during imaging-guided breast biopsy.

Dasatinib, Nilotinib, Ponatinib Increase Vascular Occlusive Events

Dasatinib, Nilotinib, Ponatinib Increase Vascular Occlusive Events

Dasatinib, nilotinib, and ponatinib, used in the treatment of patients with chronic myeloid leukemia (CML) increase vascular occlusive events.

Conference Coverage

Targeted Hormone-radiation Treatment Shows Promise in Midgut Neuroendocrine Tumors

Tumor growth may be substantially slowed by the novel therapy 177Lutetium-DOTATATE (Lutathera), according to early results from a phase III study of patients with previously treated, advanced midgut neuroendocrine tumors.

Reduced Toxicity, Similar Efficacy Achieved With Novel Regimen for Advanced Rectal Cancer

No difference in local efficacy was found between two treatment regimens for colorectal cancer: short-course (5-day) radiation followed by consolidation chemotherapy before surgery and standard 5-week chemoradiation.

Lethal Prostate Cancer Risk Lower With Regular Aspirin Use

The risk of lethal prostate cancer, but not of overall, high-grade, or advanced cancers, was reduced with regular aspirin use.

Low-income Breast Cancer Survivors Benefit From Personalized Survivorship Care Plans

Survivorship care plans led to improved outcomes in a randomized, controlled trial reported at the American Society of Clinical Oncology 2016 Cancer Survivorship Symposium.

Adolescent and Young-adult Survivors of Hodgkin Lymphoma May Not Adhere to Follow-up Recommendations

Within the first year posttreatment, more than half of Hodgkin lymphoma survivors did not receive all recommended care. However, 96% had their recommended oncology visits and 70% had the recommended laboratory tests within the first 5 years.

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